(Z)-1-butylthio-1-phenyl-2-phenylethynyl-4-triisopropylsilyl-1-buten-3-yne | 1269800-77-2

• 分子结构分类: 有机化合物 - 木脂素、新木脂素和相关化合物
• 英文名称: (Z)-1-butylthio-1-phenyl-2-phenylethynyl-4-triisopropylsilyl-1-buten-3-yne
• 英文别名: [(3Z)-3-[butylsulfanyl(phenyl)methylidene]-5-phenylpenta-1,4-diynyl]-tri(propan-2-yl)silane
• CAS: 1269800-77-2
• 化学式: C₃₁H₄₀SSi
• 分子量: 472.81
• InChiKey: YISZXMRKJNTLAC-KTMFPKCZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.2
• 重原子数：
  33
• 可旋转键数：
  12
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  25.3
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  1-butylthio-2-(triisopropylsilyl)ethyne 、 1，4-二苯基丁二炔 在 hydridotetakis(triphenylphosphine)rhodium(I) 、 二甲基苯基磷 作用下， 以 1,3-二甲基-2-咪唑啉酮 为溶剂， 反应 6.0h， 以43%的产率得到(Z)-1-butylthio-1-phenyl-2-phenylethynyl-4-triisopropylsilyl-1-buten-3-yne
  参考文献：
  名称：

  Rhodium-catalyzed carbothiolation reaction of 1-alkylthio-1-alkynes

  摘要：

  A rhodium complex derived from RhH(PPh(3))(4) and Me(2)PhP catalyzed the carbothiolation reaction of 1-alkylthio-1-alkynes and 1,4-diaryl-1,3-butadiynes giving (Z)-4-alkylthio-4-aryl-3-arylethynyl-3-buten-1-ynes. Terminal alkynes such as 1-decyne and (t-butylthio)acetylene underwent the carbothiolation reaction using a RhH(PPh(3))(4)-dppb catalyst. The reactions proceeded via cis-addition with C-C bond formation at the less hindered acetylene carbon. (C) 2011 Published by Elsevier Ltd.

  DOI：

  10.1016/j.tetlet.2010.12.065

文献信息

• Rhodium-catalyzed carbothiolation reaction of 1-alkylthio-1-alkynes
  作者：Mieko Arisawa、Yui Igarashi、Yoko Tagami、Masahiko Yamaguchi、Chizuko Kabuto

  DOI：10.1016/j.tetlet.2010.12.065

  日期：2011.2

  A rhodium complex derived from RhH(PPh(3))(4) and Me(2)PhP catalyzed the carbothiolation reaction of 1-alkylthio-1-alkynes and 1,4-diaryl-1,3-butadiynes giving (Z)-4-alkylthio-4-aryl-3-arylethynyl-3-buten-1-ynes. Terminal alkynes such as 1-decyne and (t-butylthio)acetylene underwent the carbothiolation reaction using a RhH(PPh(3))(4)-dppb catalyst. The reactions proceeded via cis-addition with C-C bond formation at the less hindered acetylene carbon. (C) 2011 Published by Elsevier Ltd.