2-hydroxy-2,6-dimethyl-heptan-4-one | 59357-12-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-hydroxy-2,6-dimethyl-heptan-4-one
• 英文别名: 2-Hydroxy-2,6-dimethyl-heptan-4-on；2-Hydroxy-2,6-dimethylheptan-4-one
• CAS: 59357-12-9
• 化学式: C₉H₁₈O₂
• 分子量: 158.241
• InChiKey: DBAVLLPPTGKXNM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  11
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-hydroxy-2,6-dimethyl-heptan-4-one 在 草酸 作用下， 生成 2,6-dimethyl-2-hepten-4-one
  参考文献：
  名称：

  Bonnier; de Gaudemaris, Bulletin de la Societe Chimique de France, 1954, p. 997,1001

  摘要：

  DOI：
• 作为产物：
  描述：

  6-羟基-2,6-二甲基-庚-2-烯-4-酮 在 镍 作用下， 70.0 ℃ 、13.73 MPa 条件下， 生成 2-hydroxy-2,6-dimethyl-heptan-4-one
  参考文献：
  名称：

  Bonnier; de Gaudemaris, Bulletin de la Societe Chimique de France, 1954, p. 997,1001

  摘要：

  DOI：

文献信息

• Efficient general synthesis of 1,2- and 1,3-diols in high enantiomeric excess via the intramolecular asymmetric reduction of the corresponding ketoalkyl diisopinocampheylborinate intermediates
  作者：P.Veeraraghavan Ramachandran、Zhi-Hui Lu、Herbert C. Brown

  DOI：10.1016/s0040-4039(96)02447-1

  日期：1997.2

  The first successful asymmetric reduction of unhindered aliphatic ketones with B-chlorodiisopinocampheylborane is reported. In contrast to the reduction in high ee of aralkyl ketones, such as acetophenone, with the reagent, the reduction of unhindered dialkyl ketones, such as 3-methyl-2-butanone, provides only poor ee. However, treatment of α- and β-hydroxyketones with one equiv of diisopinocampheylborane

  据报道，首次成功地使用B-氯二异opinocampheylborane不对称地还原了不受阻碍的脂肪族酮。与用试剂降低芳烷基酮（如苯乙酮）的高ee相反，未受阻的二烷基酮（如3-甲基-2-丁酮）的降低仅提供较差的ee。然而，用一当量的二异硫代樟脑硼烷或B-氯二异硫代樟脑硼烷处理α-和β-羟基酮迅速产生相应的酮烷基二异硫代樟脑硼酸酯中间体，然后将其容易地进行分子内还原。该反应顺序，然后进行氧化后处理，可以合成84-≥99％对映体过量的1,2-和1,3-二醇。
• Sur les enolates lithies de cetones. Cetolisation mixte univoque et regiospecifique
  作者：Françoise Gaudemar-bardone、Marcel Gaudemar

  DOI：10.1016/s0022-328x(00)91373-1

  日期：1976.1
• POSITIVE PHOTOSENSITIVE RESIN COMPOSITION AND METHOD FOR FORMING PATTERNS BY USING THE SAME
  申请人：LIU Chi-Ming

  公开号：US20120328799A1

  公开（公告）日：2012-12-27

  A photosensitive resin composition and a method for forming patterns by using the same are disclosed. The photosensitive resin composition comprises a novolac resin (A), an ortho-naphthoquinone diazide sulfonic acid ester (B) and a ketol solvent (C). The novolac resin (A) includes a high-ortho novolac resin (A-1) that has ortho-ortho methylene bonding to all methylene bonding in a ratio of 18% to 25%, and a weight ratio (A-1)/(C) of the high-ortho novolac resin (A-1) to the ketol solvent (C) is 0.1 to 2.0, thereby exhibiting excellent temporal stability and further forming patterns with superior film to thickness uniformity and high resolution.
• BIOCATALYSIS CELLS AND METHODS
  申请人：REGENTS OF THE UNIVERSITY OF MINNESOTA

  公开号：US20140329275A1

  公开（公告）日：2014-11-06

  In one aspect, the invention provides a recombinant microbial cell modified to exhibit increased biosynthesis of a biosynthetic product compared to a wild-type control. In some cases, the biosynthetic product can be isocaproate; in other cases the biosynthetic product can be isovalerate. In another aspect, the invention provides methods of constructing such recombinant cells. In yet another aspect, the invention provides methods of using the cells to produce the biosynthetic product. In yet another aspect, the invention provides methods of harvesting organic acids from a fermentation culture.
• [EN] PROCESS FOR PRODUCING DIBK<br/>[FR] PRODCÉDÉ POUR LA PRODUCTION DE DIBK
  申请人：RHODIA POLIAMIDA E ESPECIALIDADES LTDA

  公开号：WO2012080809A1

  公开（公告）日：2012-06-21

  La présente invention concerne un procédé de production de diisobutyl cétone (DIBK) consistant à mettre en présence de l'acétone, de la méthylisobutyl cétone (MIBK) et un catalyseur multifonctionnel capable d'effectuer une réaction d'aldolisation, une déshydratation et une hydrogénation.