3-Isopropylamino-butan-2-one | 84300-46-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3-Isopropylamino-butan-2-one
• 英文别名: 2-Butanone, 3-[(1-methylethyl)amino]-；3-(propan-2-ylamino)butan-2-one
• CAS: 84300-46-9
• 化学式: C₇H₁₅NO
• mdl: MFCD18813351
• 分子量: 129.202
• InChiKey: YKBYTZGYGUZKTA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  9
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.857
• 拓扑面积：
  29.1
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  3-Isopropylamino-butan-2-one 生成 3-[propan-2-yl(prop-2-enyl)amino]butan-2-one
  参考文献：
  名称：

  FRIARY, R.;KIRBY, G. W., J. CHEM. SOC. CHEM. COMMUN., 1984, N 20, 1383

  摘要：

  DOI：
• 作为产物：
  描述：

  (2,2-Dimethoxy-1-methyl-propyl)-isopropyl-amine 在 磷酸 作用下， 生成 3-Isopropylamino-butan-2-one
  参考文献：
  名称：

  Kimpe de, Norbert; Verhe, Roland; Buyck de, Laurent, Synthesis, 1982, # 8, p. 765 - 767

  摘要：

  DOI：

文献信息

• AZIDO NUCLEOSIDES AND NUCLEOTIDE ANALOGS
  申请人：Beigelman Leonid

  公开号：US20120070415A1

  公开（公告）日：2012-03-22

  Disclosed herein are nucleosides, nucleotides and analogs thereof, pharmaceutical compositions that include one or more of nucleosides, nucleotides and analogs thereof, and methods of synthesizing the same. Also disclosed herein are methods of ameliorating and/or treating a disease and/or a condition, including an infection from a paramyxovirus and/or an orthomyxovirus, with a nucleoside, a nucleotide and an analog thereof. Examples of viral infections include a respiratory syncytial viral (RSV) and influenza infection.

  本文披露了核苷、核苷酸及其类似物，包括一个或多个核苷、核苷酸及其类似物的药物组合物，以及合成它们的方法。本文还披露了利用核苷、核苷酸和其类似物来改善和/或治疗疾病和/或状况的方法，包括来自副黏病毒和/或正黏病毒的感染。病毒感染的例子包括呼吸道合胞病毒（RSV）和流感感染。
• KIMPE, N.;VERHE, R.;BUYCK, L.;MOENS, L.;SULMON, P.;SCHAMP, N., SYNTHESIS, BRD, 1982, N 9, 765-767
  作者：KIMPE, N.、VERHE, R.、BUYCK, L.、MOENS, L.、SULMON, P.、SCHAMP, N.

  DOI：——

  日期：——
• PROTEIN INTERACTION REPORTER AGENTS AND METHODS FOR USING SAME
  申请人：Bruce James E.

  公开号：US20100047814A1

  公开（公告）日：2010-02-25

  Particular aspects provide novel protein interaction reporter (PIR) compounds (e.g., formulas I and II), comprising at least two protein reactive moieties (e.g., N-hydroxysuccinamide), each linked to a reporter moiety (e.g., mass reporter) by a covalent labile bond that is differentially cleavable with respect to peptide bonds (e.g., by a method such as collisional activation in a mass spectrometer, activation by electron capture dissociation (ECD), photoactivation, etc.), wherein the reporter moiety is operatively releasable from the PIR agent upon cleavage of the labile bonds, the released reporter moiety having a characteristic identifying property or label (e.g., m/z value). Particular PIRs comprise a mass reporter moiety, and further comprise an affinity group, (e.g., biotin), linked to the PIR (e.g., to the mass reporter moiety) by a selectively cleavable bone (e.g. photo-labile bond)). Additional aspects provide methods for characterizing intermolecular or intramolecular protein interactions using one or more inventive PIR compounds.
• NANOMATERIAL COMPOSITIONS, SYNTHESIS, AND ASSEMBLY
  申请人：Rhode Island Hospital

  公开号：US20170362238A1

  公开（公告）日：2017-12-21

  Compositions or an assembly of a series of biomimetic compounds include chemical structures that mimic or structurally resemble a nucleic acid base pair. Complexes of nanotubes and agents are useful to deliver agents into the cells or bodily tissues of individuals for therapeutic and diagnostic purposes. Exemplary compounds include those of Formula (I), (III), (V) or (VII), or of Formula (II), (IV), (VI) or (VIII).
• US7524925B2
  申请人：——

  公开号：US7524925B2

  公开（公告）日：2009-04-28