6-(dimethylcarbamoyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid | 497141-19-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 6-(dimethylcarbamoyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid
• CAS: 497141-19-2
• 化学式: C₁₆H₁₈N₂O₃
• 分子量: 286.331
• InChiKey: JUZFWMMSQNBCGD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  21
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  69.6
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• SUBSTITUTED TETRAHYDROQUINOLINES AS ANTIBACTERIAL AGENTS
  申请人：FRECHETTE Roger

  公开号：US20090203726A1

  公开（公告）日：2009-08-13

  A method of treating a subject for a bacterial infection includes administering to a subject in need of treatment for a bacterial infection an effective amount of a compound represented by structural formula (I-a), or a pharmaceutically acceptable salt, solvate, or hydrate thereof. The variables in structural formula (I-a) are described herein.
• [EN] SUBSTITUTED TETRAHYDROQUINOLINES AS ANTIBACTERIAL AGENTS<br/>[FR] TÉTRAHYDROQUINOLINES SUBSTITUÉES UTILISÉES EN TANT QU'AGENTS ANTIBACTÉRIENS
  申请人：MAXTHERA INC

  公开号：WO2009073550A2

  公开（公告）日：2009-06-11

  A method of treating a subject for a bacterial infection includes administering to a subject in need of treatment for a bacterial infection an effective amount of a compound represented by structural formula (I-a), or a pharmaceutically acceptable salt, solvate, or hydrate thereof. The variables in structural formula (I-a) are described herein.