1,3-diphenylpentadecan-1-one | 138695-43-9

• 分子结构分类: 有机化合物 - 木脂素、新木脂素和相关化合物
• 英文名称: 1,3-diphenylpentadecan-1-one
• CAS: 138695-43-9
• 化学式: C₂₇H₃₈O
• 分子量: 378.598
• InChiKey: XXZPAALTFFLZOT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.8
• 重原子数：
  28
• 可旋转键数：
  15
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.52
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  1-碘十二烷 、 苯亚甲基苯乙酮 生成 1,3-diphenylpentadecan-1-one
  参考文献：
  名称：

  Conjugate addition reactions of organosamarium species via in situ transmetalation to copper(I) salts

  摘要：

  Preformed organosamarium species, available by reduction of aryl or alkyl halides with SmI2, were treated with copper(I) salts to effect in situ transmetalation and conjugate addition to enones. In a series of copper(I) salts, CuI.P(OEt)3 gave best results in combination with 2 equiv of organosamarium reagent. This new method allows the multiple formation of carbon-carbon bonds through a combination of radical and cuprate chemistry.

  DOI：

  10.1021/jo00032a027

文献信息

• Conjugate addition reactions of organosamarium species via in situ transmetalation to copper(I) salts
  作者：Michael J. Totleben、Dennis P. Curran、Peter Wipf

  DOI：10.1021/jo00032a027

  日期：1992.3

  Preformed organosamarium species, available by reduction of aryl or alkyl halides with SmI2, were treated with copper(I) salts to effect in situ transmetalation and conjugate addition to enones. In a series of copper(I) salts, CuI.P(OEt)3 gave best results in combination with 2 equiv of organosamarium reagent. This new method allows the multiple formation of carbon-carbon bonds through a combination of radical and cuprate chemistry.