2-(Azocan-1-yl)-7-chloro-4-methylquinoline | 418789-62-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 2-(Azocan-1-yl)-7-chloro-4-methylquinoline
• CAS: 418789-62-5
• 化学式: C₁₇H₂₁ClN₂
• 分子量: 288.8
• InChiKey: KWHRYDIOJUBQRP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  20
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.47
• 拓扑面积：
  16.1
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• Compositions and methods for altering immune function
  申请人：Howard Laurence

  公开号：US20070041981A1

  公开（公告）日：2007-02-22

  The present invention relates to molecules that stabilize and/or enhance CD154 activity, compositions comprising these molecules, methods for using these molecules and compositions (e.g., pharmaceutical compositions) comprising them. Specifically, the molecules can be used for enhancing immune function (e.g., enhancing Th1 cytokine expression), stimulating immune responses, and/or treating certain disorders (e.g., cancer, infectious disease, and immune compromised states). The invention also relates to kits and compositions comprising the molecules.
• US7601355B2
  申请人：——

  公开号：US7601355B2

  公开（公告）日：2009-10-13
• [EN] METABOLIC KINASE MODULATORS AND METHODS OF USE AS PESTICIDES<br/>[FR] MODULATEURS METABOLIQUES DE KINASES ET LEURS PROCEDES D'UTILISATION EN TANT QUE PESTICIDES
  申请人：EXELIXIS INC

  公开号：WO2005087742A1

  公开（公告）日：2005-09-22

  This invention relates to compounds that can be used as pesticides, in particular their use as agents in the control of pests for crop protection, human and animal health, and home and garden applications. More specifically, this invention relates to the use of compounds that modulate metabolic kinase pathways of pests, in particular that inhibit the ethanolamine kinase pathways of pests, the disruption of which proves lethal.
• [EN] COMPOSITIONS AND METHODS FOR ALTERING IMMUNE FUNCTION<br/>[FR] COMPOSITIONS ET MÉTHODES POUR ALTÉRER UNE FONCTION IMMUNITAIRE
  申请人：UNIV NORTHWESTERN

  公开号：WO2007053189A2

  公开（公告）日：2007-05-10

  [EN] The present invention relates to molecules that stabilize and/or enhance CD 154 activity, compositions comprising these molecules, methods for using these molecules and compositions (e.g., pharmaceutical compositions) comprising them. Specifically, the molecules can be used for enhancing immune function (e.g., enhancing ThI cytokine expression), stimulating immune responses, and/or treating certain disorders (e.g., cancer, infectious disease, and immune compromised states). The invention also relates to kits and compositions comprising the molecules.
  [FR] La présente invention concerne des molécules qui stabilisent et/ou accentuent l'activité de CD 154, des compositions qui comprennent lesdites molécules, des méthodes pour utiliser lesdites molécules et des compositions (par exemple, des compositions pharmaceutiques) qui les contiennent. Spécifiquement, lesdites molécules peuvent être utilisées pour accentuer une fonction immunitaire (par exemple, accentuer l'expression de la cytokine ThI), pour stimuler des réponses immunitaires et/ou traiter certains troubles (par exemple, cancers, maladies infectieuses et états immunitaires compromis). L'invention concerne aussi des nécessaires et des compositions qui contiennent lesdites molécules.