8-乙基-4(1H)-喹啉酮 | 23096-83-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 中文名称: 8-乙基-4(1H)-喹啉酮
• 英文名称: 8-Ethyl-4-hydroxychinolin
• 英文别名: 8-Ethyl-4-quinolinol；8-ethyl-1H-quinolin-4-one
• CAS: 23096-83-5
• 化学式: C₁₁H₁₁NO
• 分子量: 173.214
• InChiKey: YBQQVKSIRLQGQW-UHFFFAOYSA-N

物化性质

• 熔点：
  166 °C
• 沸点：
  335.0±22.0 °C(Predicted)
• 密度：
  1.170±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  13
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  29.1
• 氢给体数：
  1
• 氢受体数：
  2

安全信息

• 海关编码：
  2933499090

文献信息

• Ethylenically unsaturated monomers for thickener compositions
  申请人：Bobsein Barrett Richard

  公开号：US20100286434A1

  公开（公告）日：2010-11-11

  New ethylenically unsaturated monomers are provided that can be (co)polymerized to provide a composition and method whereby the same group that is attached to or within the backbone of an associative thickener is reversibly switched between being hydrophilic and hydrophobic in nature. When the group that is attached to or within the backbone is rendered hydrophilic, the aqueous thickener is pourable and readily incorporated into aqueous polymer compositions. When this group is rendered hydrophobic, the thickener performs its thickening function efficiently. Switching is readily accomplished by adjusting the pH of the associative thickener composition and the aqueous polymer composition being thickened. The thickeners are prepared from the novel monomers by an aqueous solution polymerization.

  提供了新的具有乙烯基不饱和性的单体，可以进行(共)聚合以提供一种组合物和方法，其中连接到或在联合增稠剂骨架内的相同基团在亲水性和疏水性之间可逆地切换。当连接到或在骨架内的基团变为亲水性时，水性增稠剂是可倾倒的，并且容易与水性聚合物组成物混合。当这个基团变为疏水性时，增稠剂有效地执行其增稠功能。通过调整联合增稠剂组合物和被增稠的水性聚合物组成物的pH值，可以轻松实现切换。这些增稠剂通过水溶液聚合从新单体制备而成。
• Thickener composition and method for thickening aqueous systems
  申请人：Bobsein Barrett Richard

  公开号：US20100076145A1

  公开（公告）日：2010-03-25

  A polymer composition with blocks of hydrophobes attached to or within the backbone of an associative thickener. The blocks are composed of two or more units of the same or different hydrophobes whereby the hydrophobe is reversibly switched between being hydrophilic and hydrophobic in nature. When the hydrophobe is rendered hydrophilic, the aqueous thickener is pourable and readily incorporated into aqueous polymer compositions. When this hydrophobe is rendered hydrophobic, the thickener performs its thickening function efficiently, especially in tinted systems. Switching is readily accomplished by adjusting the pH of the associative thickener composition and the aqueous polymer composition being thickened.

  一种聚合物组合物，其包括连接到或嵌入到关联增稠剂骨架上的疏水块。这些块由相同或不同的两个或多个疏水单元组成，其中疏水性可逆地在亲水性和疏水性之间切换。当疏水变为亲水时，水性增稠剂可倾倒且容易混合到水性聚合物组合物中。当疏水变为疏水时，增稠剂可以有效地发挥其增稠功能，特别是在有色系统中。通过调整关联增稠剂组合物和被增稠的水性聚合物组合物的pH值，可轻松实现切换。
• Polymer Composition
  申请人：Rohm and Haas Company

  公开号：EP2112206A1

  公开（公告）日：2009-10-28

  A composition and method whereby the same group that is attached to or within the backbone of an associative thickener is reversibly switched between being hydrophilic and hydrophobic in nature. When the group that is attached to or within the backbone is rendered hydrophilic, the aqueous thickener is pourable and readily incorporated into aqueous polymer compositions. When this group is rendered hydrophobic, the thickener performs its thickening function efficiently. Switching is readily accomplished by adjusting the pH of the associative thickener composition and the aqueous polymer composition being thickened.

  一种组合物和方法，在这种组合物和方法中，附着在缔合增稠剂骨架上或骨架内的相同基团可在亲水性和疏水性之间进行可逆转换。当附着在骨架上或骨架内的基团被亲水化时，水性增稠剂具有流动性，并容易与水性聚合物组合物结合。当该基团变为疏水性时，增稠剂就能有效地发挥其增稠功能。通过调节缔合型增稠剂组合物和被增稠的水性聚合物组合物的 pH 值，可轻松实现切换。
• Thickened compositions and method for thickening aqueous polymer compositions
  申请人：Rohm and Haas Company

  公开号：EP2166044A1

  公开（公告）日：2010-03-24

  Thickened aqueous compositions, and a method for controlling viscosity drift for thickened aqueous compositions comprising a pigment, a polymer containing polymerized units of phosphate- or phosphonate-containing monomers, and an acid suppressible thickener.

  增稠水基组合物，以及控制增稠水基组合物粘度漂移的方法，该组合物包含颜料、含磷酸或含膦酸单体聚合单元的聚合物，以及可抑制酸的增稠剂。
• Pyranopyrazole and pyrazolopyridine immunomodulators for treatment of autoimmune diseases
  申请人：The Rockefeller University

  公开号：US11312723B2

  公开（公告）日：2022-04-26

  Pyranoyrazoles and pyrazolopyridines of formula I or formula II are disclosed: These compounds inhibit Coagulation Factor XIIa in the presence of thrombin and other coagulation factors. They are useful to treat autoimmune diseases.

  公开了式 I 或式 II 的吡喃并吡唑和吡唑并吡啶： 这些化合物在凝血酶和其他凝血因子存在的情况下抑制凝血因子 XIIa。它们可用于治疗自身免疫性疾病。