6-deoxycatalpol | 99499-99-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 6-deoxycatalpol
• 英文别名: (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-[[(1S,2S,4S,6R,10S)-2-(hydroxymethyl)-3,9-dioxatricyclo[4.4.0.02,4]dec-7-en-10-yl]oxy]oxane-3,4,5-triol
• CAS: 99499-99-7
• 化学式: C₁₅H₂₂O₉
• 分子量: 346.334
• InChiKey: DHSHYQJABUIJDG-HXHBHVAVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.2
• 重原子数：
  24
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.87
• 拓扑面积：
  141
• 氢给体数：
  5
• 氢受体数：
  9

反应信息

• 作为反应物：
  描述：

  6-deoxycatalpol 在 palladium 10% on activated carbon 、 氢气 作用下， 以 甲醇 为溶剂， 反应 2.0h， 以100%的产率得到3,4-dihydro-6-deoxycatalpol
  参考文献：
  名称：

  Iridoid and Acyclic Monoterpene Glycosides, Kankanosides L, M, N, O, and P from Cistanche tubulosa

  摘要：

  从肉苁蓉（大戟科植物）的新鲜茎中分离出了三种鸢尾苷类化合物，即坎坎苷 L、M 和 N，以及两种非环单萜苷类化合物，即坎坎苷 O 和 P，还有八种鸢尾苷类化合物、五种非环单萜苷类化合物、三种苯丙苷类化合物和四种木质素苷类化合物。根据化学和物理化学证据阐明了它们的结构。

  DOI：

  10.1248/cpb.58.1403

文献信息

• Monoterpene Constituents from Cistanche tubulosa-Chemical Structures of Kankanosides A-E and Kankanol-
  作者：Haihui Xie、Toshio Morikawa、Hisashi Matsuda、Seikou Nakamura、Osamu Muraoka、Masayuki Yoshikawa

  DOI：10.1248/cpb.54.669

  日期：——

  Four new iridoid glycosides, kankanosides A (1), B (2), C (3), and D (4), a chlorinated iridoid, kankanol (5), and an acyclic monoterpene glycoside, kankanoside E (6), were isolated from the methanolic extract of dried stems of Cistanche tubulosa (SCHRENK) R. WIGHT (Orobanchaceae) together with 16 known compounds. The structures of these new compounds (1-6) were determined on the basis of the chemical

  分离出四个新的鸢尾苷苷，kankanosides A（1），B（2），C（3）和D（4），氯化的鸢尾酮，kankanol（5）和无环单萜苷，kankanoside E（6）。从肉of蓉肉干（SCHRENK）R. WIGHT（Orobanchaceae）的甲醇提取物中提取，还有16种已知化合物。这些新化合物（1-6）的结构是根据化学和物理化学证据确定的。
• Iridoid glucosides from Utricularia australis and Pinguicula vulgaris (lentibulariaceae)
  作者：Søren Damtoft、Søren Rosendal Jensen、Bent Juhl Nielsen

  DOI：10.1016/s0031-9422(00)83027-7

  日期：1985.1

  Utricularia australis contained 6-deoxycatalpol, a new iridoid glucoside, besides aucubin, gardoside and mussaenosidic acid. From Pinguicula vulgaris was isolated catalpol, globularin and 10-( Z )-cinnamoyl-catalpol, the latter being a new compound. Thus, the iridoids found in Lentibulariaceae belong to structural types which are common in Scrophulariaceae and related families.

  摘要 澳洲荨麻中含有6-脱氧梓醇，一种新的环烯醚萜苷，含有桃叶珊瑚苷、gardoside和mussaenosidic acid。从普通品木香中分离出梓醇、球蛋白和10-(Z)-肉桂酰-梓醇，后者是一种新化合物。因此，在豆科植物中发现的环烯醚萜属于玄参科及其相关科中常见的结构类型。
• [EN] COMPOSITION HAVING HEAT SHOCK PROTEIN INDUCTION ACTIVITY AND COMPRISING COMPOUND ISOLATED FROM EUCOMMIA ULMOIDES<br/>[FR] COMPOSITION PRÉSENTANT UNE ACTIVITÉ D'INDUCTION DE PROTÉINES DE CHOC THERMIQUE ET CONTENANT UN COMPOSÉ ISOLÉ À PARTIR D'EUCOMMIA ULMOIDES
  申请人：UNIV EWHA IND COLLABORATION

  公开号：WO2013172640A1

  公开（公告）日：2013-11-21

  본 발명은 열충격단백질 유도 활성을 갖는 두충으로부터 분리된 화합물을 포함하는 약학적 조성물에 관한 것이다. 본 발명에 따른 두충으로부터 분리된 화합물은 열충격단백질 유도 활성을 갖고 있으며 특히, HSF 1, HSP 27 및/또는 HSP 70의 발현을 조절할 수 있다. 이에 따라서 열충격단백질의 유도를 통해서 세포의 보호 및 재생 효과가 있으며 신경질환, 소화기질환, 장질환, 신질환, 안질환, 심혈관질환 또는 피부질환의 치료 또는 예방에 유용하게 사용될 수 있다. 또한, 손상된 피부 세포 재생용 화장료 조성물로 유용하게 사용될 수 있다.
• Iridoid and Acyclic Monoterpene Glycosides, Kankanosides L, M, N, O, and P from Cistanche tubulosa
  作者：Toshio Morikawa、Yingni Pan、Kiyofumi Ninomiya、Katsuya Imura、Dan Yuan、Masayuki Yoshikawa、Takao Hayakawa、Osamu Muraoka

  DOI：10.1248/cpb.58.1403

  日期：——

  Three iridoid glycosides, kankanosides L, M, and N, and two acyclic monoterpene glycosides, kankanosides O and P, were isolated from fresh stems of Cistanche tubulosa (Orobanchaceae) together with eight iridoid glycosides, five acyclic monoterpene glycosides, three phenylpropanoid glycosides, and four lignan glycosides. Their structures were elucidated on the basis of chemical and physicochemical evidence.

  从肉苁蓉（大戟科植物）的新鲜茎中分离出了三种鸢尾苷类化合物，即坎坎苷 L、M 和 N，以及两种非环单萜苷类化合物，即坎坎苷 O 和 P，还有八种鸢尾苷类化合物、五种非环单萜苷类化合物、三种苯丙苷类化合物和四种木质素苷类化合物。根据化学和物理化学证据阐明了它们的结构。