4-(3-methoxy-phenoxy)-benzo[4,5]furo[3,2-d]pyrimidine | 65023-95-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 4-(3-methoxy-phenoxy)-benzo[4,5]furo[3,2-d]pyrimidine
• 英文别名: 4-(3-Methoxyphenoxy)[1]benzofuro[3,2-d]pyrimidine；4-(3-methoxyphenoxy)-[1]benzofuro[3,2-d]pyrimidine
• CAS: 65023-95-2
• 化学式: C₁₇H₁₂N₂O₃
• mdl: MFCD15077406
• 分子量: 292.294
• InChiKey: FVEWBYLNFYAAJJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  22
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  57.4
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  4-氯苯并呋喃[3,2d]吡啶 以60%的产率得到
  参考文献：
  名称：

  SANGAPURE S. S.; AGASIMUNDIN Y. S., INDIAN J. CHEM. , 1977, B 15, NO 5, 485-487

  摘要：

  DOI：

文献信息

• Sangapure,S.S.; Agasimundin,Y.S., Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1977, vol. 15, p. 485 - 487
  作者：Sangapure,S.S.、Agasimundin,Y.S.

  DOI：——

  日期：——
• CASEIN KINASE 1delta (CK 1delta) INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODE-GENERATIVE DISEASES SUCH AS TAUOPATHIES
  申请人：Sheridan Joseph M.

  公开号：US20140031547A1

  公开（公告）日：2014-01-30

  The invention relates to pharmaceutical compositions comprising casein kinase 1 delta (CK1δ) and to the use of said inhibitors in the treatment of neurodegenerative disorders such as Alzheimer's disease.
• CASEIN KINASE 1delta (CK 1delta) INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES SUCH AS TAUOPATHIES
  申请人：Electrophoretics Limited

  公开号：US20160354375A1

  公开（公告）日：2016-12-08

  The invention relates to pharmaceutical compositions comprising casein kinase 1 delta (CK1δ) and to the use of said inhibitors in the treatment of neurodegenerative disorders such as Alzheimer's disease.
• SANGAPURE S. S.; AGASIMUNDIN Y. S., INDIAN J. CHEM. <IJOC-AP>, 1977, B 15, NO 5, 485-487
  作者：SANGAPURE S. S.、 AGASIMUNDIN Y. S.

  DOI：——

  日期：——