10-(3-(triisopropoxysilyl)propyl)acridin-9(10H)-one | 1192344-59-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 10-(3-(triisopropoxysilyl)propyl)acridin-9(10H)-one
• 英文别名: 10-[3-Tri(propan-2-yloxy)silylpropyl]acridin-9-one；10-[3-tri(propan-2-yloxy)silylpropyl]acridin-9-one
• CAS: 1192344-59-4
• 化学式: C₂₅H₃₅NO₄Si
• 分子量: 441.643
• InChiKey: GHUVPWGZXMOAGM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.76
• 重原子数：
  31
• 可旋转键数：
  10
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.48
• 拓扑面积：
  48
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  10-(3-(triisopropoxysilyl)propyl)acridin-9(10H)-one 、 1-溴-2,6-二甲氧基苯 在 magnesium 作用下， 以 四氢呋喃 为溶剂， 反应 14.0h， 生成
  参考文献：
  名称：

  Acridinium Salt-Based Fluoride and Acetate Chromofluorescent Probes: Molecular Insights into Anion Selectivity Switching

  摘要：

  A series of acridinium salt-based probes capable of detecting fluoride and acetate anions via a nucleophilic attack at the C9 position of the acridinium moiety is reported. The formation of corresponding acridane displays drastic changes, in both UV-vis absorption and fluorescence emission. The sensing mechanism is a reversible process upon treating either tetrafluoroborate salt or an acid.

  DOI：

  10.1021/ol901935g
• 作为产物：
  描述：

  、 异丙醇 在 吡啶 作用下， 以 二氯甲烷 为溶剂， 以239 mg的产率得到10-(3-(triisopropoxysilyl)propyl)acridin-9(10H)-one
  参考文献：
  名称：

  Acridinium Salt-Based Fluoride and Acetate Chromofluorescent Probes: Molecular Insights into Anion Selectivity Switching

  摘要：

  A series of acridinium salt-based probes capable of detecting fluoride and acetate anions via a nucleophilic attack at the C9 position of the acridinium moiety is reported. The formation of corresponding acridane displays drastic changes, in both UV-vis absorption and fluorescence emission. The sensing mechanism is a reversible process upon treating either tetrafluoroborate salt or an acid.

  DOI：

  10.1021/ol901935g

文献信息

• Acridinium Salt-Based Fluoride and Acetate Chromofluorescent Probes: Molecular Insights into Anion Selectivity Switching
  作者：Yu-Chen Lin、Chao-Tsen Chen

  DOI：10.1021/ol901935g

  日期：2009.11.5

  A series of acridinium salt-based probes capable of detecting fluoride and acetate anions via a nucleophilic attack at the C9 position of the acridinium moiety is reported. The formation of corresponding acridane displays drastic changes, in both UV-vis absorption and fluorescence emission. The sensing mechanism is a reversible process upon treating either tetrafluoroborate salt or an acid.