6-Quinolinol, 8-[(4-amino-1-methylbutyl)amino]- | 80038-07-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 6-Quinolinol, 8-[(4-amino-1-methylbutyl)amino]-
• 英文别名: 8-(5-aminopentan-2-ylamino)quinolin-6-ol
• CAS: 80038-07-9
• 化学式: C₁₄H₁₉N₃O
• 分子量: 245.32
• InChiKey: ZJVLLKFLBQUFMW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  18
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  71.2
• 氢给体数：
  3
• 氢受体数：
  4

文献信息

• PRIMAQUINE DERIVATIVES FOR USE IN THE PREVENTION AND/OR THE TREATMENT OF DISORDERS ASSOCIATED TO GAMMAHERPESVIRUS
  申请人：Assistance Publique - Hôpitaux de Paris

  公开号：EP3474843B1

  公开（公告）日：2020-10-28
• HYDROPHOBIC MODIFIED PEPTIDES AND THEIR USE FOR LIVER SPECIFIC TARGETING
  申请人：Mier Walter

  公开号：US20140038886A1

  公开（公告）日：2014-02-06

  The present invention relates to hydrophobic modified peptides for the specific delivery of compounds to the liver, preferably to hepatocytes, in vitro as well as in vivo. The present invention relates to pharmaceutical compositions comprising said hydrophobic modified peptide(s) and the compound(s) to be specifically delivered to the liver. The present invention furthermore relates to the use of the inventive hydrophobic modified peptides as well as to a method for the prevention and/or treatment of liver diseases or disorders.