2,2'-dimethyl-4,4'-cyclopentylidene-di-phenol | 50628-59-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,2'-dimethyl-4,4'-cyclopentylidene-di-phenol
• 英文别名: 1.1-Bis-(4-hydroxy-3-methyl-phenyl)-cyclopentan；2,2'-Dimethyl-4,4'-cyclopentyliden-di-phenol；4,4'-Cyclopentane-1,1-diylbis(2-methylphenol)；4-[1-(4-hydroxy-3-methylphenyl)cyclopentyl]-2-methylphenol
• CAS: 50628-59-6
• 化学式: C₁₉H₂₂O₂
• 分子量: 282.382
• InChiKey: OBWVOELZAMJXRD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.6
• 重原子数：
  21
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.37
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  一氯频呐酮 、 2,2'-dimethyl-4,4'-cyclopentylidene-di-phenol 在 sodium hydride 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 3.0h， 以67%的产率得到1-(4-{1-[4-(3,3-Dimethyl-2-oxo-butoxy)-3-methyl-phenyl]-cyclopentyl}-2-methyl-phenoxy)-3,3-dimethyl-butan-2-one
  参考文献：
  名称：

  Ligands with a 3,3-diphenylpentane skeleton for nuclear vitamin D and androgen receptors: Dual activities and metabolic activation

  摘要：

  Ligands possessing dual vitamin D-3 (VD3)-agonistic and androgen-antagonistic activities with various activity spectra were prepared based on a substituted 3,3-diphenylpentane (DPP) skeleton. Among the compounds, (R,S)-DPP-1023 [(R,S)-7b] and (S,S)-DPP-0123 [(S,S)-7c] showed the most potent vitamin D-3-agonistic activity [with potency comparable to that of 1 alpha,25-dihydroxyvitamin D-3 (1,25-VD3)] and nuclear androgen receptor (AR)-binding activity (with higher affinity than that of hydroxyflutamide), respectively. Metabolic activation (reduction of the carbonyl group) of pivaloyl analogs [DPP- 1113 (3a), DPP- 10 13 (3b), DPP-0113 (3c), and DPP-0013 (3d)] in HL-60 cells was found to be necessary for binding to nuclear vitamin D-3 receptor (VDR). (c) 2006 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmc.2006.04.039
• 作为产物：
  描述：

  邻甲酚 、 环戊酮 在 盐酸 作用下， 生成 2,2'-dimethyl-4,4'-cyclopentylidene-di-phenol
  参考文献：
  名称：

  Campbell, Proceedings of the Royal Society of London. Series B, Biological sciences, 1940, vol. 129, p. 528,537

  摘要：

  DOI：

文献信息

• Optically active compound and photosensitive resin composition
  申请人：——

  公开号：US20030211421A1

  公开（公告）日：2003-11-13

  A photoactive compound is used in combination with a photosensitizer, represented by the following formula (1): A −[( J ) m −( X-Pro )] n (1) wherein A represents a hydrophobic unit comprising at least one kind of hydrophobic groups selected from a hydrocarbon group and a heterocyclic group, J represents a connecting group, X-Pro represents a hydrophilic group protected by a protective group Pro which is removable by light exposure, m represents 0 or 1, and n represents an integer of not less than 1. The protective group Pro may be removable by light exposure in association with the photosensitizer (especially, a photo acid generator), or may be a hydrophobic protective group. The hydrophilic group may be a hydroxyl group or a carboxyl group. The photoactive compound has high sensitivity to a light source of short wavelength beams, for resist application, therefore, the photoactive compound is advantageously used for forming a pattern with high resolution.

  一种光活性化合物与光敏剂结合使用，由以下公式（1）表示： A −[( J ) m −( X-Pro )] n (1) 其中，A代表至少包括一种从烃基和杂环基中选择的疏水基的疏水单元，J代表连接基团，X-Pro代表由光照可去除的保护基团Pro保护的亲水基团，m代表0或1，n代表不少于1的整数。 保护基团Pro可以与光敏剂（特别是光酸发生剂）一起通过光照可去除，也可以是疏水保护基团。亲水基团可以是羟基或羧基。光活性化合物对短波长光源具有很高的敏感性，用于光刻应用，因此，该光活性化合物有利于形成具有高分辨率的图案。
• METHOD FOR PRODUCING BISCHLOROFORMATE COMPOUND, POLYCARBONATE OLIGOMER HAVING SMALL NUMBER OF MONOMERS AND SOLUTION CONTAINING BISCHLOROFMATE COMPOUND
  申请人：Hikosaka Takaaki

  公开号：US20120101292A1

  公开（公告）日：2012-04-26

  A dihydric phenol compound represented by the following formula (2), a phosgene compound, and an aliphatic tertiary amine are mixed together using a hydrophobic organic solvent to produce bischloroformate that is represented by the following formula (1) and has an average number of repeating units (n) of 1.99 or less. In the formulae (1) and (2), Ar is a divalent aromatic group.

  使用疏水性有机溶剂混合以下化学式（2）表示的二元酚化合物、光气化合物和脂肪族三级胺，以产生以下化学式（1）表示的双氯甲酸酯，其平均重复单元数（n）为1.99或更少。在化学式（1）和（2）中，Ar是二价芳香族基。
• Method of making silicone copolycarbonates having random and blocky substructures
  申请人：General Electric Company

  公开号：US20030065122A1

  公开（公告）日：2003-04-03

  The invention relates to a method of preparing silicone copolycarbonates which incorporate both blocky and random substructures. Such silicone-containing copolycarbonates are useful in the preparation of a variety of molded articles such as optical disks. The structure of the compositions prepared by the method of the invention is determined by the method of preparation used and may be used to control physical properties. The copolymers are prepared by forming in a first step an intermediate silicone copolycarbonate possessing either a blocky or random structure and reactive endgroups, and then appending additional structural in a second step which is complimentary to the first step and produces a product silicone copolycarbonate having both random and blocky substructures. The repeat units I and II appended in the second step may be the same or different as those repeat units I and II incorporated in the first step.

  本发明涉及一种制备既包含块状结构又包含随机结构的硅氧烷共聚碳酸酯的方法。这种含硅氧烷的共聚碳酸酯在制备各种模塑制品，如光盘方面有用。本发明所制备的组合物的结构由所用的制备方法确定，并可用于控制物理性能。该共聚物的制备方法是通过在第一步中形成一种中间硅氧烷共聚碳酸酯，其具有块状或随机结构和反应末端基团，然后在第二步中附加与第一步互补的额外结构，从而产生既具有随机又具有块状亚结构的硅氧烷共聚碳酸酯产品。在第二步中附加的重复单元I和II可以与第一步中包含的重复单元I和II相同或不同。
• Method of improving abrasion resistance of plastic article using functionalized polymers and article produced thereby
  申请人：Tamaki Ryo

  公开号：US20070085242A1

  公开（公告）日：2007-04-19

  The invention includes embodiments that relate to a method of improving the abrasion resistance of a plastic article. The method comprises: (a) providing a composition comprising at least one e-beam active thermoplastic polymeric material; (b) forming an article from the composition of step (a); and (c) exposing the article formed in step (b) to an electron beam source. The invention also includes embodiments that relate to an article comprising an abrasion resistant surface.

  该发明涉及改善塑料制品耐磨性的方法。该方法包括：(a)提供一个组成物，包括至少一种电子束活性热塑性聚合物材料；(b)从步骤(a)的组成物形成一件制品；以及(c)将在步骤(b)中形成的制品暴露于电子束源。该发明还涉及一种具有耐磨表面的制品。
• POLYCARBONATE POLYMER, COATING LIQUID, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY
  申请人：Hikosaka Takaaki

  公开号：US20100233603A1

  公开（公告）日：2010-09-16

  A polycarbonate polymer includes: a monomer unit represented by a formula (1A) below; and a monomer unit represented by a formula (2). A haze of a solution that is obtained by dissolving the polycarbonate polymer in THF (tetrahydrofuran) at a concentration of 10 mass % is 5% or less (according to JIS K7105, optical path length of 10 mm). In the formula (1A), R and R′ each independently represent a hydrogen atom, a halogen atom, an alkyl group having 1 to 12 carbon atoms or a substituted or unsubstituted aryl group having 6 to 12 carbon atoms; n1 is an integer in a range of 2 to 4; and n2 is an integer in a range of 25 to 220; and in the formula (2), Ar represents a divalent aromatic group.

  一种聚碳酸酯聚合物包括：由以下式（1A）表示的单体单位；和由式（2）表示的单体单位。将聚碳酸酯聚合物以10质量％的浓度在THF（四氢呋喃）中溶解得到的溶液的浑浊度小于或等于5％（根据JIS K7105，光程为10毫米）。在式（1A）中，R和R'各自独立表示氢原子，卤素原子，具有1到12个碳原子的烷基或具有6到12个碳原子的取代或未取代芳基基团；n1是2到4之间的整数；n2是25到220之间的整数；在式（2）中，Ar表示二价芳香基团。