NSC260610 | 67047-17-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: NSC260610
• 英文别名: N,N'-bis(3-methoxyacridin-9-yl)hexane-1,6-diamine
• CAS: 67047-17-0
• 化学式: C₃₄H₃₄N₄O₂
• 分子量: 530.67
• InChiKey: FLTPBXAPYZIIEV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.2
• 重原子数：
  40
• 可旋转键数：
  11
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  68.3
• 氢给体数：
  2
• 氢受体数：
  6

文献信息

• METHODS AND COMPOUNDS FOR REGULATING APOPTOSIS
  申请人：Reed John C.

  公开号：US20090118135A1

  公开（公告）日：2009-05-07

  An assay for determining compounds that inhibit activity of a BCl-2 protein, or affect conversion of Bcl-2 from an antiapoptotic to a proapoptotic form are described. In addition, compounds that modulate the function of anti-apoptotic proteins such as Bcl-2 and related Bcl-2 family members are identified.
• MICROWELL PLATE FOR HIGH-THROUGHPUT DETECTION AND APPLICATION THEREOF
  申请人：SHANGHAI JIAOTONG UNIVERSITY

  公开号：US20160348148A1

  公开（公告）日：2016-12-01

  A microwell plate for high-throughput detection is provided. The microwell plate includes a plurality of microwell groups, the microwell group includes at least a first microwell and a second microwell, and the microwell group further includes a gas diffusion passage for communicating the first microwell and the second microwell. The application of the microwell plate to high-throughput detection of gas produced through biochemical reaction is also provided. The described methodology is applicable to high-throughput detection and can prevent biological and/or chemical reaction and target substance detection from being interfered with each other, and particularly can attain high-throughput screening of enzyme activity regulators.