2,2,4,4,5,5-Hexamethyl-1,3-dioxolan | 17226-67-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2,2,4,4,5,5-Hexamethyl-1,3-dioxolan
• 英文别名: 2,2,4,4,5,5-Hexamethyl-1,3-dioxolane
• CAS: 17226-67-4
• 化学式: C₉H₁₈O₂
• 分子量: 158.241
• InChiKey: WMZFIRPHBANWEP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2,2,4,4,5,5-Hexamethyl-1,3-dioxolan 、 以 四氢呋喃 为溶剂， 以13.2 mg的产率得到(4aR,6R,7R,7aS)-2,2-ditert-butyl-6-phenyl-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4a,6,7,7a-tetrahydro-4H-thieno[3,2-d][1,3,2]dioxasiline
  参考文献：
  名称：

  An Access to the β-Anomer of 4′-Thio-C-ribonucleosides: Hydroboration of 1-C-Aryl- or 1-C-Heteroaryl-4-thiofuranoid Glycals and Its Regiochemical Outcome

  摘要：

  We have developed a novel method for the synthesis of the beta-anomer of 4'-thio-C-ribonucleosides from 3,5-O-(di-tert-butylsilylene)-4-thiofuranoid glycal. Palladium-catalyzed coupling of 1-tributylstannyl-4-thiofuranoid glycal with iodobenzene or a heteroaryl halide gave 1-C-phenyl- or 1-C-heteroaryl-glycals. Hydroboration of these glycals proceeded at the alpha-face, and subsequent alkaline hydrogen peroxide treatment of the resulting 2'-alpha-borane furnished the respective beta-anomer of 4'-thio-C-ribonucleosides. These results demonstrate that this synthetic method has a wider scope in terms of heterocyclic base structure. During this study, unexpected Markovnikov-oriented hydroboration has been observed to lead to the respective 1'-alpha-boranes. These 1'-boranes were converted into either the ring-opened structure or the 2'-deoxy derivatives depending upon their stability.

  DOI：

  10.1021/jo201100n
• 作为产物：
  描述：

  频哪醇 、 2,2-二甲氧基丙烷 在 丁基三氯化锡 作用下， 反应 1.0h， 生成 2,2,4,4,5,5-Hexamethyl-1,3-dioxolan
  参考文献：
  名称：

  基于全甲基化环醚的稳定锂氧电池电解质

  摘要：

  基于醚的电解质由于其相对较高的稳定性而常用于Li-O 2电池（LOB）。但是它们仍然易于通过氢提取反应受到超氧化物或单线态氧的攻击，这导致长期运行期间性能下降。本文中，我们提出了甲基化的环状醚2,2,4,4,5,5-六甲基-1,3-二氧戊环（HMD），作为LOB的稳定电解质溶剂。这样的化合物在醚的α-碳上不包含任何氢原子，从而避免了氢的夺取反应。结果，该溶剂在超氧化物或单线态氧的存在下表现出优异的稳定性。另外CO 2禁止在充电过程中进化。使用基于HMD的电解质的LOB可以运行157个循环，是基于1,3-二氧戊环（DOL）或1,2-二甲氧基乙烷（DME）的电解质的LOB的4倍。

  DOI：

  10.1002/anie.201812983

文献信息

• METHOD FOR PRODUCING AROMATIC COMPOUND
  申请人：Sumitomo Chemical Company, Limited

  公开号：US20150322101A1

  公开（公告）日：2015-11-12

  A method is provided for producing an aromatic compound, including a step of mixing a compound represented by formula (A) and a compound represented by formula (B): in the presence of at least one phosphine compound selected from the group consisting of a phosphine represented by formula (C) and a phosphonium salt represented by formula (F): a base, a palladium compound, and an aprotic organic solvent.

  提供一种生产芳香化合物的方法，包括以下步骤：在至少一种磷化物化合物的存在下，将由化学式(A)表示的化合物与由化学式(B)表示的化合物混合；所述磷化物化合物选择自由化学式(C)表示的磷化物和由化学式(F)表示的磷酸盐；还包括碱、钯化合物和无水有机溶剂。
• PROCESSES FOR PRODUCING A FLUOROSULFONYL GROUP-CONTAINING COMPOUND AND A COMPOUND LED FROM THE FLUOROSULFONYL GROUP-CONTAINING COMPOUND
  申请人：OKAZOE Takashi

  公开号：US20080287694A1

  公开（公告）日：2008-11-20

  A fluorosulfonyl group-containing compound having a high polymerization reactivity, a process for its production, a sulfonyl group-containing polymerizable monomer led from the sulfonyl group-containing compound, and a polymer obtainable by polymerizing the sulfonyl group-containing polymerizable monomer, are provided. A compound (3) is fluorinated to form a compound (4), and then, the compound (4) is subjected to a decomposition reaction to produce a compound (5). A preferred compound (5-1) of the compound (5) is thermally decomposed to produce a compound (7-1) having a high polymerization reactivity. wherein R A is a bivalent organic group such as a fluoroalkylene group, R AF is a group having R A fluorinated, or the same group as R A , each of R B to R D which are independent of one another, is a hydrogen atom, etc., each of R BF to R DF is a fluorine atom, etc., R E is a monovalent organic group, R EF is a group having R E fluorinated, or the same group as R E , E is a bivalent connecting group, E F is the same group as E, or a group having E fluorinated, E F1 is a group formed by scission of E F , each of X 1 to X 3 is a hydrogen atom, etc., and each of X 1F to X 3F is a fluorine atom, etc.

  提供了一种含有氟磺酰基团的高聚合反应性化合物、其制备方法、由含有磺酰基团的聚合单体引导的磺酰基团含量的聚合物以及通过聚合磺酰基团含量的聚合单体获得的聚合物。化合物（3）被氟化形成化合物（4），然后，化合物（4）经历分解反应产生化合物（5）。化合物（5）的优选化合物（5-1）被热分解产生具有高聚合反应性的化合物（7-1）。 其中，RA是双价有机基团，例如氟烷基团，RAF是RA氟化的基团，或者与RA相同的基团，RB到RD中的每一个都是独立的，是氢原子等，RBF到RDF中的每一个都是氟原子等，RE是单价有机基团，REF是RE氟化的基团，或者与RE相同的基团，E是双价连接基团，EF是与E相同的基团，或者是E氟化的基团，EF1是通过EF断裂形成的基团，X1到X3中的每一个都是氢原子等，X1F到X3F中的每一个都是氟原子等。
• Aminopropenoates as Fungicides
  申请人：DUBOST Christophe

  公开号：US20110152322A1

  公开（公告）日：2011-06-23

  The present invention relates to aminopropenoate derivatives, the process of their preparation, intermediate compounds, their use as fungicide active agents, particularly in the form of fungicide compositions, and methods for the control of phytopathogenic fungi, notably of plants and in material protection, using these compounds or compositions.

  本发明涉及氨基丙烯酸酯衍生物，其制备过程，中间化合物，它们作为杀真菌活性剂的用途，特别是作为杀真菌组合物的形式，以及使用这些化合物或组合物控制植物病原真菌，尤其是在材料保护方面的方法。
• Cyanoenamines and Their use as Fungicides
  申请人：Benting Jürgen

  公开号：US20130298291A1

  公开（公告）日：2013-11-07

  The present invention relates to cyanoenamine derivatives, their process of preparation, intermediate compounds, their use as fungicide active agents, particularly in the form of fungicide compositions, and methods for the control of phytopathogenic fungi, notably of plants and in material protection, using these compounds or compositions.

  本发明涉及氰基烯胺衍生物、其制备方法、中间体化合物、它们作为杀真菌剂活性剂的用途，特别是以真菌杀菌剂组合物的形式，以及使用这些化合物或组合物控制植物病原真菌，尤其是植物和材料保护的方法。
• Method for producing 2-alkylcarbonylnaphtho[2,3-b]furan-4,9-dione-related substance, and said related substance
  申请人：Sumitomo Dainippon Pharma Co., Ltd.

  公开号：US10738023B2

  公开（公告）日：2020-08-11

  Provided is a method for producing a 2-alkylcarbonylnaphtho[2,3-b]furan-4,9-dione-related substance, which is suitable for the production on an industrial scale. The present invention provides: a method for producing an intermediate for the production of a 2-alkylcarbonyl[2,3-b]furan-4,9-dione, which comprises reacting a 1-butyne derivative in which a ketone or an alcohol is protected with a 2-hydroxy-1,4-naphthoquinone derivative having a leaving group at position-3 in a solvent in the presence of a metal or a metal compound and a base; and a substance relating to the intermediate.

  本发明提供了一种生产 2-烷基羰基萘并[2,3-b]呋喃-4,9-二酮相关物质的方法，该方法适于工业化生产。本发明提供了：一种生产 2-烷基羰基[2,3-b]呋喃-4,9-二酮的中间体的方法，该方法包括在金属或金属化合物和碱存在下，在溶剂中使酮或醇被保护的 1-丁炔衍生物与位置-3 上有离去基团的 2-羟基-1,4-萘醌衍生物反应；以及一种与该中间体有关的物质。

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