acetic acid-(2-chloro-3-hydroxy-propyl ester) | 859053-78-4

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 卤代醇
• 英文名称: acetic acid-(2-chloro-3-hydroxy-propyl ester)
• 英文别名: Essigsaeure-(2-chlor-3-hydroxy-propylester)；(2-Chloro-3-hydroxypropyl) acetate
• CAS: 859053-78-4
• 化学式: C₅H₉ClO₃
• 分子量: 152.578
• InChiKey: PXTGSZCVWLPUAR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  9
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  乙酸烯丙酯 在 次氯酸 作用下， 生成 acetic acid-(2-chloro-3-hydroxy-propyl ester)
  参考文献：
  名称：

  Bigot, Annales de Chimie (Cachan, France), 1891, vol. <6> 22, p. 482

  摘要：

  DOI：

文献信息

• Wegscheider; Zmerzlikar, Monatshefte fur Chemie, 1913, vol. 34, p. 1066
  作者：Wegscheider、Zmerzlikar

  DOI：——

  日期：——
• Bigot, Annales de Chimie (Cachan, France), 1891, vol. <6> 22, p. 482
  作者：Bigot

  DOI：——

  日期：——
• Batch, semi-continuous or continuous hydrochlorination of glycerin with reduced volatile chlorinated hydrocarbon by-products and chloracetone levels
  申请人：Kruper J. William

  公开号：US20080015369A1

  公开（公告）日：2008-01-17

  The present invention relates to a process for converting a multihydroxylated-aliphatic hydrocarbon or ester thereof to a chlorohydrin, by contacting the multihydroxylated-aliphatic hydrocarbon or ester thereof starting material with a source of hydrogen chloride at superatmospheric, atmospheric and subatmospheric pressure conditions for a sufficient time and at a sufficient temperature, preferably wherein such contracting step is carried out without substantial removal of water, to produce the desired chlorohydrin product; wherein the desired product or products can be made in high yield without substantial formation of undesired overchlorinated byproducts; said process carried out without a step undertaken to specifically remove volatile chlorinated hydrocarbon by-products or chloroacetone, wherein the combined concentration of volatile chlorinated hydrocarbon by-products and chloroacetone is less than 2000 ppm throughout any stage of the said process.
• Method for Making Chlorohydrin in Liquid Phase in the Presence of Heavy Compounds
  申请人：Gilbeau Patrick

  公开号：US20080194884A1

  公开（公告）日：2008-08-14

  Process for preparing a chlorohydrin, wherein a polyhydroxylated aliphatic hydrocarbon, an ester of a polyhydroxylated aliphatic hydrocarbon or a mixture thereof is subjected to reaction with a chlorinating agent in the presence of a liquid phase comprising heavy compounds other than the polyhydroxylated aliphatic hydrocarbon and having a boiling temperature under a pressure of 1 bar absolute which is at least 15° C. greater than the boiling temperature of the chlorohydrin under a pressure of 1 bar absolute.
• BATCH, SEMI-CONTINUOUS OR CONTINUOUS HYDROCHLORINATIONOF GLYCERIN WITH REDUCED VOLATILE CHLORINATED HYDROCARBON BY-PRODUCTS AND CHLOROACETONE LEVELS
  申请人：Kruper William J.

  公开号：US20110124890A1

  公开（公告）日：2011-05-26

  The present invention relates to a process for converting a multihydroxylated-aliphatic hydrocarbon or ester thereof to a chlorohydrin, by contacting the multihydroxylated-aliphatic hydrocarbon or ester thereof starting material with a source of hydrogen chloride at superatmospheric, atmospheric and subatmospheric pressure conditions for a sufficient time and at a sufficient temperature, preferably wherein such contracting step is carried out without substantial removal of water, to produce the desired chlorohydrin product; wherein the desired product or products can be made in high yield without substantial formation of undesired overchlorinated byproducts; said process carried out without a step undertaken to specifically remove volatile chlorinated hydrocarbon by-products or chloroacetone, wherein the combined concentration of volatile chlorinated hydrocarbon by-products and chloroacetone is less than 2000 ppm throughout any stage of the said process.