(1-ethynyl-cyclohexyloxymethyl)-oxirane | 7312-56-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (1-ethynyl-cyclohexyloxymethyl)-oxirane
• 英文别名: 2-{[(1-Ethynylcyclohexyl)oxy]methyl}oxirane；2-[(1-ethynylcyclohexyl)oxymethyl]oxirane
• CAS: 7312-56-3
• 化学式: C₁₁H₁₆O₂
• 分子量: 180.247
• InChiKey: YAFBKWFCKDWOKE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  21.8
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  (1-ethynyl-cyclohexyloxymethyl)-oxirane 、 硫脲 以55%的产率得到
  参考文献：
  名称：

  GVERDTSITELI I. M.; GELASHVILI E. S.; YASHVILI N. M., SAKARTVELOS CCP METSNIEREBATA AKADEMIIS MOAMBE, SOOBSHCH. AN GRUZSSR, 197+

  摘要：

  DOI：

文献信息

• Synthesis and Anticancer Activity of 5-(Propargyloxymethyl)-2-oxazolidinones
  作者：R.B. Fugitt、L.C. Martinelli

  DOI：10.1002/jps.2600620637

  日期：1973.6

  determine the feasibility of producing a tissue-specific anticancer agent, a series of 2-oxazolidinones bearing an alkynoxymethyl side chain in the 5-position was prepared. These compounds were submitted to the National Cancer Institute for testing against L-1210 and/or P-388 tumor test systems. None of the compounds showed significant anticancer activity. The synthetic procedures and NMR spectral properties

  摘要：为了确定生产组织特异性抗癌剂的可行性，制备了一系列在5位带有炔氧基甲基侧链的2-恶唑烷酮。这些化合物已提交给美国国家癌症研究所，以针对L-1210和/或P-388肿瘤测试系统进行测试。这些化合物均未显示出显着的抗癌活性。描述了标题化合物的合成方法和NMR光谱性质。
• HYDROXYL-FUNCTIONAL UNSATURATED POLYAMINE SILICONE LIGAND SUITABLE FOR QUANTUM DOT COMPOSITIONS AND ARTICLES
  申请人：3M INNOVATIVE PROPERTIES COMPANY

  公开号：US20200216752A1

  公开（公告）日：2020-07-09

  A quantum dot article comprises (a) a first barrier layer, (b) a second barrier layer, and (c) a quantum dot layer between the first barrier layer and the second barrier layer, the quantum dot layer comprises light-emitting nanoparticles dispersed in a cured matrix; wherein the quantum dot layer further comprises a hydroxyl-functional unsaturated polyamine silicone ligand that is the reaction product of a polyamine silicone ligand and an unsaturated monofunctional epoxy compound.