N-(3-nitrophenyl)-2-quinolin-8-yloxyacetamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: N-(3-nitrophenyl)-2-quinolin-8-yloxyacetamide
• 化学式: C17H13N3O4
• 分子量: 323.3
• InChiKey: YBESBHMZKZKKNB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  24
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  97
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• Oxyacetamide compounds useful for stimulating or inducing the growth and/or retarding the loss of keratin fibers
  申请人：Rozot Roger

  公开号：US20070092467A1

  公开（公告）日：2007-04-26

  Oxyacetamide compounds that are inhibitors of type-1 15-hydroxyprostaglandin dehydrogenase (15-PGDH) and which have the formula (I), or salts and/or solvates thereof: are useful for inducing and/or stimulating the growth of human keratin fibers, e.g., human head hair and/or eyelashes, and/or for retarding the loss and/or increasing the density thereof and/or for caring for and/or making up such keratin fibers.

  氧乙酰胺类化合物是类型1 15-羟基前列腺素脱氢酶（15-PGDH）的抑制剂，其化学式为（I），或其盐和/或溶剂，可用于诱导和/或刺激人类角蛋白纤维（例如，人类头发和/或睫毛）的生长，或减缓其脱落和/或增加密度和/或护理和/或美化这些角蛋白纤维。
• Administration of 2-oxyacetamide compounds for promoting and/or inducing and/or stimulating the pigmentation of keratin materials and/or for limiting the depigmentation and/or bleaching thereof
  申请人：Rozot Roger

  公开号：US20080166310A1

  公开（公告）日：2008-07-10

  A regime or regimen for promoting and/or inducing and/or stimulating the pigmentation of keratin materials and/or for preventing and/or limiting the depigmentation and/or bleaching and/or for preventing and/or limiting the canities thereof, more particularly of human keratin fibers such as the hair, beard hair, moustache hair, the eyelashes and the eyebrows, includes administering to an individual in need of such treatment at least one 2-oxyacetamide compound of formula (I), or a salt and/or solvate thereof: