4-Quinolinamine, decahydro-1-methyl-

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 4-Quinolinamine, decahydro-1-methyl-
• 英文别名: 1-methyl-3,4,4a,5,6,7,8,8a-octahydro-2H-quinolin-4-amine
• 化学式: C₁₀H₂₀N₂
• mdl: MFCD06016188
• 分子量: 168.28
• InChiKey: BLYUFWSKCMEZSN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  29.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• NOVEL COMPOUNDS
  申请人：HALSALL Christopher Thomas

  公开号：US20080009482A1

  公开（公告）日：2008-01-10

  There is provided a compound of formula (I): processes for the manufacture thereof, pharmaceutical compositions thereof and uses in therapy.

  提供了一个化合物的化学式(I)： 其制备方法，药物组合物以及在治疗中的用途。
• FUSED PYRIMIDO COMPOUNDS
  申请人：AstraZeneca AB

  公开号：EP2046793A2

  公开（公告）日：2009-04-15
• PYRIDINE AND PYRAZINE DERIVATIVES USEFUL IN THE TREATMENT OF CELL PROLIFERATIVE DISORDERS
  申请人：AstraZeneca AB

  公开号：EP2215085B1

  公开（公告）日：2011-09-07
• ANTIMICROBIAL COMPOUNDS, COMPOSITIONS, AND USES THEREOF
  申请人：Lakewood Amedex, Inc.

  公开号：US20210139522A1

  公开（公告）日：2021-05-13

  Antimicrobial compounds and compositions of Formulas (I) to (III) and methods of use are disclosed. Another aspect of the present disclosure provides a pharmaceutical composition comprising a compound according to Formula (I) to (III), or a pharmaceutically acceptable salt thereof, and one or more pharmaceutically acceptable carriers, excipients, or diluents. Another aspect of the present disclosure provides a method of treating a bacterial infection in a patient in need thereof, the method of comprising administering an effective amount of a compound according to Formula (I) to (III), or a pharmaceutically acceptable salt thereof, to the patient.
• US7709471B2
  申请人：——

  公开号：US7709471B2

  公开（公告）日：2010-05-04