2-[1,3]Dithian-2-yl-5-(2-[1,3]dithian-2-yl-ethyl)-cyclohexanol | 185559-42-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-[1,3]Dithian-2-yl-5-(2-[1,3]dithian-2-yl-ethyl)-cyclohexanol
• 英文别名: 2-(1,3-Dithian-2-yl)-5-[2-(1,3-dithian-2-yl)ethyl]cyclohexan-1-ol；2-(1,3-dithian-2-yl)-5-[2-(1,3-dithian-2-yl)ethyl]cyclohexan-1-ol
• CAS: 185559-42-6
• 化学式: C₁₆H₂₈OS₄
• 分子量: 364.662
• InChiKey: GNOXUSPNIXHGAA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.1
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  121
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  1,3-二噻烷 、 2-(8-chlorooctyl)oxirane 在 正丁基锂 作用下， 生成 5-(2-Chloro-ethyl)-2-[1,3]dithian-2-yl-cyclohexanol 、 2-[1,3]Dithian-2-yl-5-(2-[1,3]dithian-2-yl-ethyl)-cyclohexanol
  参考文献：
  名称：

  Aggregative activation and carbanion chemistry : complex base deprotonation and directed functionalisation of dithioacetals

  摘要：

  Bis(phenylthio)methane and [1,3]-dithiane were efficiently deprotonated by the NaNH2-Et(OCH2CH2)(2)-ONa complex base. A marked behaviour difference was observed between the sodium carbanion of [1,3]-dithiane and the corresponding lithio-derivative; A ''radicaioid'' mechanism is proposed to explain the results observed. Copyright (C) 1996 Elsevier Science Ltd

  DOI：

  10.1016/s0040-4020(96)00972-6

文献信息

• Aggregative activation and carbanion chemistry : complex base deprotonation and directed functionalisation of dithioacetals
  作者：Philippe Gros、Philippe Hansen、Paul Caubére

  DOI：10.1016/s0040-4020(96)00972-6

  日期：1996.11

  Bis(phenylthio)methane and [1,3]-dithiane were efficiently deprotonated by the NaNH2-Et(OCH2CH2)(2)-ONa complex base. A marked behaviour difference was observed between the sodium carbanion of [1,3]-dithiane and the corresponding lithio-derivative; A ''radicaioid'' mechanism is proposed to explain the results observed. Copyright (C) 1996 Elsevier Science Ltd