(2,3-dihydrothieno[3,4-b][1,4]dioxin-2-yl)methyl methacrylate | 1202744-63-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2,3-dihydrothieno[3,4-b][1,4]dioxin-2-yl)methyl methacrylate
• 英文别名: 2,3-Dihydrothieno[3,4-b][1,4]dioxin-3-ylmethyl 2-methylprop-2-enoate；2,3-dihydrothieno[3,4-b][1,4]dioxin-3-ylmethyl 2-methylprop-2-enoate
• CAS: 1202744-63-5
• 化学式: C₁₁H₁₂O₄S
• 分子量: 240.28
• InChiKey: PEYBRLZYKHXXDW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  16
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  73
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  羟甲基 EDOT 、 甲基丙烯酰氯 在 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 0.33h， 以93%的产率得到(2,3-dihydrothieno[3,4-b][1,4]dioxin-2-yl)methyl methacrylate
  参考文献：
  名称：

  Flexible Conductive Polymer Patterns from Vapor Polymerizable and Photo-Cross-Linkable EDOT

  摘要：

  We explored direct photopatterning of a vapor polymerizable and photo-cross-linkable 3,4-ethylenedioxythiopene (EDOT) to make it suitable for use in electronics applications. We prepared a conductive polymer, PEDOT-MA, using vapor phase polymerization (VPP) of the (2,3-dihydrothieno-[3,4-b][1,4]dioxin-2-yl)methyl methacrylate (EDOT-MA) and photochemically induced a conductivity change of the PEDOT-MA film to ensure a flexible conductive pattern. The room-temperature conductivity (sigma(RT)) of the PEDOT-MA Film on PET was 30-120 S/cm, depending oil the oxidant layer thickness and was increased similar to 30% when the PEDOT-MA film was doped with aqueous solution of p-toluenesulfonic acid. Photoreaction of PEDOT-MA decreased the sigma(RT) to 1.7 x 10(-3) S/cm because of the photo-cross-linking of the side chain. The transparency of the conductive films was tuned using the vapor polymerization time to control the film thickness. The photo-cross-linking reaction of the side chain generated micropatterns having line widths of 50-0.9 mu m, in which the light-exposed areas appeared as bleached and less conductive. A diffractive, flexible, conductive film with 41% of diffraction efficiency was obtained from the line-patterned film having a spacing of 0.9 mu m.

  DOI：

  10.1021/ma9025306

文献信息

• Methods of selective cell attachment/detachment, cell patternization and cell harvesting by means of near infrared rays
  申请人：Industry-Academic Cooperation Foundation, Yonsei University

  公开号：US10385303B2

  公开（公告）日：2019-08-20

  The present invention relates to a method for selective cell attachment/detachment, cell patternization and cell harvesting by means of near infrared rays. More particularly, conducting polymers or metal oxides having exothermic characteristics upon irradiation of near infrared light is used as a cell culture scaffold, thus selectively attaching/detaching cells without an enzyme treatment. The scaffold has an effect of promoting proliferation or differentiation of stem cells, and therefore, can be used as a stem cell culture scaffold. The scaffold enables cell attachment/detachment without temporal or spatial restrictions, thus enabling cell patternization.

  本发明涉及一种利用近红外线进行选择性细胞附着/脱落、细胞图案化和细胞收获的方法。更具体地说，使用在近红外线照射下具有放热特性的导电聚合物或金属氧化物作为细胞培养支架，从而在不使用酶处理的情况下选择性地附着/脱落细胞。该支架具有促进干细胞增殖或分化的作用，因此可用作干细胞培养支架。该支架可使细胞不受时间或空间限制地附着/脱落，从而实现细胞模式化。
• METHOD FOR SELECTIVE CELL ATTACHMENT/DETACHMENT, CELL PATTERNIZATION AND CELL HARVESTING BY MEANS OF NEAR INFRARED RAYS
  申请人：Industry-Academic Cooperation Foundation, Yonsei University

  公开号：US20150044770A1

  公开（公告）日：2015-02-12

  The present invention relates to a method for selective cell attachment/detachment, cell patternization and cell harvesting by means of near infrared rays. More particularly, conducting polymers or metal oxides having exothermic characteristics upon irradiation of near infrared light is used as a cell culture scaffold, thus selectively attaching/detaching cells without an enzyme treatment. The scaffold has an effect of promoting proliferation or differentiation of stem cells, and therefore, can be used as a stem cell culture scaffold. The scaffold enables cell attachment/detachment without temporal or spatial restrictions, thus enabling cell patternization.
• METHODS OF SELECTIVE CELL ATTACHMENT/DETACHMENT, CELL PATTERNIZATION AND CELL HARVESTING BY MEANS OF NEAR INFRARED RAYS
  申请人：Industry-Academic Cooperation Foundation, Yonsei University

  公开号：US20170073627A1

  公开（公告）日：2017-03-16

  The present invention relates to a method for selective cell attachment/detachment, cell patternization and cell harvesting by means of near infrared rays. More particularly, conducting polymers or metal oxides having exothermic characteristics upon irradiation of near infrared light is used as a cell culture scaffold, thus selectively attaching/detaching cells without an enzyme treatment. The scaffold has an effect of promoting proliferation or differentiation of stem cells, and therefore, can be used as a stem cell culture scaffold. The scaffold enables cell attachment/detachment without temporal or spatial restrictions, thus enabling cell patternization.
• Flexible Conductive Polymer Patterns from Vapor Polymerizable and Photo-Cross-Linkable EDOT
  作者：Jeonghun Kim、Jungmok You、Eunkyoung Kim

  DOI：10.1021/ma9025306

  日期：2010.3.9

  We explored direct photopatterning of a vapor polymerizable and photo-cross-linkable 3,4-ethylenedioxythiopene (EDOT) to make it suitable for use in electronics applications. We prepared a conductive polymer, PEDOT-MA, using vapor phase polymerization (VPP) of the (2,3-dihydrothieno-[3,4-b][1,4]dioxin-2-yl)methyl methacrylate (EDOT-MA) and photochemically induced a conductivity change of the PEDOT-MA film to ensure a flexible conductive pattern. The room-temperature conductivity (sigma(RT)) of the PEDOT-MA Film on PET was 30-120 S/cm, depending oil the oxidant layer thickness and was increased similar to 30% when the PEDOT-MA film was doped with aqueous solution of p-toluenesulfonic acid. Photoreaction of PEDOT-MA decreased the sigma(RT) to 1.7 x 10(-3) S/cm because of the photo-cross-linking of the side chain. The transparency of the conductive films was tuned using the vapor polymerization time to control the film thickness. The photo-cross-linking reaction of the side chain generated micropatterns having line widths of 50-0.9 mu m, in which the light-exposed areas appeared as bleached and less conductive. A diffractive, flexible, conductive film with 41% of diffraction efficiency was obtained from the line-patterned film having a spacing of 0.9 mu m.