(E)-2-benzyl-1-phenyl-3-penten-2-ol | 1393652-84-0

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 直链 1,3-二芳基丙烷
• 英文名称: (E)-2-benzyl-1-phenyl-3-penten-2-ol
• 英文别名: (E)-2-benzyl-1-phenylpent-3-en-2-ol
• CAS: 1393652-84-0
• 化学式: C₁₈H₂₀O
• 分子量: 252.356
• InChiKey: SPMCBQMGMJFVNJ-XNJYKOPJSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  19
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  (E)-2-benzyl-1-phenyl-3-penten-2-ol 在 三乙基硅烷 作用下， 以 2,2,2-三氟乙醇 为溶剂， 反应 0.5h， 以92%的产率得到2-benzyl-1-phenyl-2-pentene
  参考文献：
  名称：

  Heteropolyacid-Catalyzed Direct Deoxygenation of Propargyl and Allyl Alcohols

  摘要：

  The combination of H-3[PW12O40]center dot nH(2)O (1 mol %) and Et3SiH led to the direct catalytic deoxygenation of propargyl alcohols, in which proper solvent selection Cl(CH2)(2)Cl vs CF3CH2OH was the key to obtaining better product yields. Under similar conditions, the deoxygenation of allyl alcohols proceeded to give thermodynamically stable alkenes with migration of the double bonds in good yields.

  DOI：

  10.1021/jo300889p
• 作为产物：
  描述：

  2-苄基-1-苯基-3-戊炔-2-醇 在 红铝 作用下， 以 甲苯 为溶剂， 以60%的产率得到(E)-2-benzyl-1-phenyl-3-penten-2-ol
  参考文献：
  名称：

  Heteropolyacid-Catalyzed Direct Deoxygenation of Propargyl and Allyl Alcohols

  摘要：

  The combination of H-3[PW12O40]center dot nH(2)O (1 mol %) and Et3SiH led to the direct catalytic deoxygenation of propargyl alcohols, in which proper solvent selection Cl(CH2)(2)Cl vs CF3CH2OH was the key to obtaining better product yields. Under similar conditions, the deoxygenation of allyl alcohols proceeded to give thermodynamically stable alkenes with migration of the double bonds in good yields.

  DOI：

  10.1021/jo300889p

文献信息

• Heteropolyacid-Catalyzed Direct Deoxygenation of Propargyl and Allyl Alcohols
  作者：Masahiro Egi、Takuya Kawai、Megumi Umemura、Shuji Akai

  DOI：10.1021/jo300889p

  日期：2012.8.17

  The combination of H-3[PW12O40]center dot nH(2)O (1 mol %) and Et3SiH led to the direct catalytic deoxygenation of propargyl alcohols, in which proper solvent selection Cl(CH2)(2)Cl vs CF3CH2OH was the key to obtaining better product yields. Under similar conditions, the deoxygenation of allyl alcohols proceeded to give thermodynamically stable alkenes with migration of the double bonds in good yields.