苯酚钾 | 100-67-4

• 物质功能分类: 有机原料 - 醇、酚、酚醇类化合物及衍生物 - 酚及其卤化、磺化、硝化或亚硝化衍生物
• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 中文名称: 苯酚钾
• 中文别名: 苯酚钾盐；苯酚鉀；苯氧化鉀
• 英文名称: phenol potassium
• 英文别名: Phenol, potassium salt (1:1)
• CAS: 100-67-4
• 化学式: C₆H₆O*K
• 分子量: 133.211
• InChiKey: RKHQZMOCQHXUBC-UHFFFAOYSA-N

物化性质

• 熔点：
  103-104 °C
• 溶解度：
  可溶于DMSO（少许）、甲醇（少许）

计算性质

• 辛醇/水分配系数(LogP)：
  1.01
• 重原子数：
  8
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

安全信息

• 危险等级：
  8
• 危险品运输编号：
  UN 2905
• 海关编码：
  2907199090
• 危险类别：
  8
• 包装等级：
  III

制备方法与用途

苯酚钾是苯酚的钾盐，广泛用作聚碳酸酯、环氧树脂、胶木、尼龙以及洗涤剂等关键成分。

反应信息

• 作为试剂：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 苯酚钾 作用下， 生成 亚老哥尔1221
  参考文献：
  名称：

  Pfankuch, Journal fur praktische Chemie (Leipzig 1954), 1872, vol. <2> 6, p. 104

  摘要：

  DOI：

文献信息

• LACTIDE POLYMERISATION
  申请人：WACKER CHEMIE AG

  公开号：US20170022320A1

  公开（公告）日：2017-01-26

  The present invention relates to a compound having the formula L a M(OR 1 ) b R 2 c X d wherein M is a metal selected from Ti, Zr and Hf; L is a ligand selected from permethylpentalene, (hydro)permethyl-pentalene, (hydro)pentalene, cyclopentadiene, indene and ethylene- or silane-bridged indene, preferably (bis)indene; R 1 is a 1-6C alkyl, substituted or unsubstituted phenyl, or a substituted or unsubstituted phenylalkylene group; R 2 is Me or Et; X is halogen; a=1 to 3, b=1 to 3, c=0 or 1 and d=0, 1, 2 or 3; and dimers thereof, the use of the compound as an initiator in the polymerisation of lactide monomer and a process for producing a polylactide performed by contacting a lactide monomer with the compound.

  本发明涉及具有以下化学式LaM(OR1)bR2cXd的化合物，其中M是从Ti、Zr和Hf中选择的金属；L是从permethylpentalene、(氢)permethyl-pentalene、(氢)pentalene、环戊二烯、茚和乙烯-或硅烷桥联的茚中选择的配体，优选为(双)茚；R1是1-6碳的烷基，取代或未取代的苯基，或取代或未取代的苯基烷基基团；R2是Me或Et；X是卤素；a=1至3，b=1至3，c=0或1，d=0、1、2或3；以及它们的二聚体，该化合物作为乳酸内酯单体聚合的引发剂的用途以及通过将乳酸内酯单体与该化合物接触来生产聚乳酸的方法。
• Process for producing aromatic hydroxycarboxylic acids
  申请人：Yamaguchi Tatsuaki

  公开号：US20060122420A1

  公开（公告）日：2006-06-08

  There is provided a process for producing an aromatic hydroxycarboxylic acid which is capable of suppressing the formation of by-products and enhancing the selectivity of the intended product and is free from any purifying step. The process is characterized in that it is obtained by reacting an alkali metal salt of an aromatic hydroxy compound and carbon dioxide in a non-proton polar solvent in the presence of a solid basic catalyst.

  提供了一种生产芳香族羟基羧酸的方法，该方法能够抑制副产物的形成，提高所需产品的选择性，并且不需要任何纯化步骤。该方法的特点在于，在非质子极性溶剂中，在固体碱性催化剂的存在下，通过反应芳香族羟基化合物的碱金属盐和二氧化碳而获得。
• Preparation of sulphophenyl esters
  申请人：Interox Chemicals Limited

  公开号：EP0220826A1

  公开（公告）日：1987-05-06

  Sulphophenyl esters can be made amongst other routes by reacting an acyl halide with a phenol sulphonate salt, but it has been suggested in the prior art that there are substantial problems or disadvantages associated with carrying out the reaction in the presence of an organic solvent such as gelation of the reaction medium or excessive reaction times. In the present invention, the process employs as organic solvent high boiling point primarily aliphatic hydrocarbons which forms with linear acyl halide a reaction medium in which products of high and/or improved purity and/or yield are obtainable without gelation and in reasonable reaction periods, especially between C₆-C₁₀ linear acyl chlorides and sodium phenol sulphonate. It has been found advantageous to pre-dry the phenol sulphonate salt by heating it when dispersed in a high boiling aliphatic or aromatic hydrocarbon solvent such that water and solvent are co-removed, with the result that in a subsequent esterification reaction with acyl halide an improvement in yield and/or purity of the sulphophenyl ester can be achieved.

  除其他途径外，还可通过酰基卤与苯酚磺酸盐反应制得硫代苯酯，但现有技术表明，在有机溶剂存在的情况下进行反应存在大量问题或缺点，如反应介质凝胶化或反应时间过长。 在本发明中，该工艺采用高沸点的主要是脂肪族烃类作为有机溶剂，它与线性酰基卤化物形成一种反应介质，在这种介质中，特别是 C₆-C₁₀ 线性酰基氯化物和苯酚磺酸钠之间的反应介质，可以获得高纯度和/或改进纯度和/或产率的产品，而不会发生凝胶化，反应时间也合理。 在苯酚磺酸钠分散在高沸点脂肪族或芳香族烃类溶剂中时，通过加热使其预干燥，从而使水和溶剂共同脱除，这样做是有利的，其结果是在随后与酰基卤化物的酯化反应中，可以提高硫代苯酯的产率和/或纯度。
• Process for preparing solid para-disodium hydroxybenzoate
  申请人：NIPPON PETROCHEMICALS COMPANY, LIMITED

  公开号：EP0243957A1

  公开（公告）日：1987-11-04

  The present invention provides a method for preparing solid p-disodium hydroxybenzoate which is characterized by comprising the steps of reacting phenol, carbon tetrachloride in an amount of 0.9 to 1.2 moles per mole of phenol and sodium hydroxide in an amount of 7 to 20 moles per mole of phenol prior to the reaction in an aqueous liquid containing 10 to 40°,° by weight of p-disodium hydroxybenzoate and or sodium chloride in the presence of a transition metal powder in an amount of 0.01 to 1.00% by weight based on the weight of a reaction system at a reaction temperature of 50 to 150°C; cooling the resulting reaction mixture to a level of - 20 to 20°C; and separating said p-disodium hydroxybenzoate therefrom.

  本发明提供了一种制备固体对羟基苯甲酸二钠的方法，其特征在于包括以下步骤：在含有对羟基苯甲酸二钠和或氯化钠（按重量计）10～40°,°的水性液体中，在50～150℃的反应温度下，使苯酚、每摩尔苯酚用量为0.9～1.2摩尔的四氯化碳和每摩尔苯酚用量为7～20摩尔的氢氧化钠在含有过渡金属粉末（按重量计）0.01～1.00％（以反应体系重量为基准）的存在下反应；将所得反应混合物冷却至-20～20℃；从中分离出所述对羟基苯甲酸二钠。
• Preparation of esters
  申请人：Interox Chemicals Limited

  公开号：EP0294073A1

  公开（公告）日：1988-12-07

  Hitherto processes proposed in recent years for preparing esters of phenol sulphonate salts by reaction between a carboxylic acid chloride and a phenol sulphonate salt place considerable emphasis upon dehydrating the reactants before they are brought into contact in an organic solvent reaction medium. The present invention avoids the problems of employing non-aqueous solvents by carrying out the reaction under aqueous conditions but with controlled alkalinity and water content, especially at a base to phenol sulphonate mole ratio of from 1.3:1 to 1.6:1 and a total water to phenol sulphonate (as the anhydrous material) of not more than 4.5:1. The reaction advantageously employs in preference only a small molar excess of carboxylic acid chloride over the phenol sulphonate and preferably has a reaction temperature controlled to below 30°C, especially 5 to 20°C. In a further improvement to the process, the difficulty of enhanced contamination with benzoic acid in the products can be ameliorated by employing a small but effective amount of a surfactant, especially an alcohol ethoxylate, in the reaction mixture. The process is especially well suited to making sodium benzoyl oxybenzene sulphonate from sodium phenol sulphonate dihydrate and benzoyl chloride.

  近年来提出的通过羧酸氯化物和苯酚磺酸盐反应制备苯酚磺酸盐酯的工艺，相当重视反应物在有机溶剂反应介质中接触前的脱水。 本发明在水性条件下进行反应，但碱度和含水量受到控制，特别是碱与酚磺酸盐的摩尔比为 1.3:1 至 1.6:1，水与酚磺酸盐（作为无水物）的总比例不超过 4.5:1，从而避免了使用非水性溶剂的问题。在反应中，羧酸氯化物的摩尔过量比酚磺酸盐的摩尔过量少，反应温度最好控制在 30℃以下，特别是 5 至 20℃。 对该工艺的进一步改进是，通过在反应混合物中使用少量但有效的表面活性剂，特别是醇乙氧基化物，可以改善产品中苯甲酸污染增强的困难。 该工艺尤其适用于从二水苯酚磺酸钠和苯甲酰氯制取苯甲酰氧基苯磺酸钠。