2-(Hexadecyloxy) cinnamic acid

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• 英文名称: 2-(Hexadecyloxy) cinnamic acid
• 英文别名: (E)-3-(2-hexadecoxyphenyl)prop-2-enoic acid
• 化学式: C₂₅H₄₀O₃
• 分子量: 388.6
• InChiKey: SHUHQKCLEHGHQP-QZQOTICOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.6
• 重原子数：
  28
• 可旋转键数：
  18
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.64
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Compounds and compositions for treating dysproliferative diseases, and methods of use thereof
  申请人：Kashfi Khosrow

  公开号：US20050182134A1

  公开（公告）日：2005-08-18

  Compounds are disclosed with activity towards killing dysproliferative cells in vitro and treating cancer in vivo. Cancers such as cancer of the colon, pancreas, prostate, lung, breast, urinary bladder, skin and liver are exemplary. Compounds, pharmaceutical compositions and methods of use are described.

  揭示了具有对体外杀灭异常增殖细胞活性的化合物，并用于治疗体内癌症。癌症如结肠癌、胰腺癌、前列腺癌、肺癌、乳腺癌、膀胱癌、皮肤癌和肝癌是示例。描述了化合物、药物组合物和使用方法。
• EP1709155A4
  申请人：——

  公开号：EP1709155A4

  公开（公告）日：2007-10-31
• COMPOUNDS AND COMPOSITIONS FOR TREATING DYSPROLIFERATIVE DISEASES, AND METHODS OF USE THEREOF
  申请人：Kashfi, Khosrow

  公开号：EP1709155A2

  公开（公告）日：2006-10-11
• US7585997B2
  申请人：——

  公开号：US7585997B2

  公开（公告）日：2009-09-08
• [EN] COMPOUNDS AND COMPOSITIONS FOR TREATING DYSPROLIFERATIVE DISEASES, AND METHODS OF USE THEREOF<br/>[FR] COMPOSES ET COMPOSITIONS DESTINES AU TRAITEMENT DE MALADIES DYSPLASIQUES, ET LEURS METHODES D'UTILISATION
  申请人：KASHFI KHOSROW

  公开号：WO2005065361A2

  公开（公告）日：2005-07-21

  Compounds are disclosed with activity towards killing dysproliferative cells in vitro and treating cancer in vivo. Cancers such as cancer of the colon, pancreas, prostate, lung, breast, urinary bladder, skin and liver are exemplary. Compounds, pharmaceutical compositions and methods of use are described.