申请人:The University of Tokushima
公开号:EP2233437A1
公开(公告)日:2010-09-29
Provided are nanofunctional silica particles having excellent functionality and quality, and capable of being mass-produced at low costs. According to the present invention, there are provided nanofunctional silica particles including a coating layer containing one or more silica compounds selected from the group consisting of mercaptopropyl trimethoxysilane (MPS), mercaptopropyl triethoxysilane (MPES), mercaptopropyl methyldimethoxysilane (MPDMS), trimethoxy[2-(7-oxabicyclo[4.1.0]-hept-3-yl)ethyl]silane (EpoPS), thiocyanatopropyl triethoxysilane (TCPS), acryloxypropyl trimethoxysilane (ACPS), and aminopropyl trimethoxysilane (APS); and functional particles in the coating layer, and being used in imaging, assay, diagnosis, treatment or the like, medicine or bioresearch.
本发明提供的纳米功能性二氧化硅颗粒具有优异的功能性和质量,并且能够以较低的成本大规模生产。根据本发明,所提供的纳米功能性二氧化硅颗粒包括一个涂层,该涂层含有一种或多种二氧化硅化合物,这些化合物选自由巯基丙基三甲氧基硅烷(MPS)、巯基丙基三乙氧基硅烷(MPES)、巯基丙基甲基二甲氧基硅烷(MPDMS)、三甲氧基[2-(7-氧杂双环[4.1.0]-庚-3-基)乙基]硅烷 (EpoPS)、硫氰酸丙基三甲氧基硅烷 (TCPS)、丙烯酰氧基丙基三甲氧基硅烷 (ACPS) 和氨基丙基三甲氧基硅烷 (APS);以及包衣层中的功能性微粒,可用于成像、检测、诊断、治疗或类似用途、医药或生物研究。