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    首页 分子通 按物质功能分类 原料药 抗寄生虫病药

    抗寄生虫病药

    按不同类型的寄生虫可分为以下几种药物：

    1. 抗疟药：主要包括用于控制疟疾症状的氯喹口服片。该药物作用于疟原虫侵入红细胞内期，有效控制症状发作。此外，还有佰氨喹口服片，主要用于防止疟疾复发和传播，特别是间日疟；乙胺嘧啶口服片则用于预防疟疾，并常与佰氨喹联用以防止复发。

    2. 抗阿米巴病和滴虫病药：甲硝达唑片（又称灭滴灵片）是一种强效的杀滴虫药物，对肠内及组织内的阿米巴原虫也有杀灭作用。它可用于治疗阴道滴虫病、阿米巴痢疾和阿米巴脓肿，并且对抗厌氧菌感染有良好疗效。

    3. 抗黑热病药：葡萄糖锑酸钠针剂可有效杀灭利什曼原虫，静脉或肌内注射后能迅速控制症状。它对黑热病患者有较好的治疗效果。

    4. 抗血吸虫病药：酒石酸锑钾针剂在治疗剂量下对血吸虫成虫有直接作用，并能使虫体生殖系统变性，是血吸虫病因治疗的主要药物。吡喹酮片是一种广谱抗寄生虫药，对日本血吸虫病、绦虫病、华支睾吸虫病和肺吸虫病等均有效。

    5. 抗丝虫病药：海群生口服片对微丝蚴及成虫均有作用，适用于治疗马来丝虫病和斑氏丝虫病。

    6. 抗肠虫药：哌嗪类药物如枸椽酸哌嗪（又称驱蛔灵）具有驱除蛔虫、蛲虫的作用；味唑类药物中的左旋味唑对蛔虫、钩虫有效，还具有免疫增强作用；甲苯味唑（又名肠虫净）对钩虫和蛲虫有较强的治疗效果；丙硫咪唑即肠虫清是一种较新的驱虫药，只需服用1次2片即可达到治疗目的。此外，还有嘧啶类药物如噻嘧啶、甲噻嘧啶，均为广谱驱虫药，适用于口服一次性或多次剂量的治疗。

    以上各类抗肠虫药通常不需要额外使用泻药，除了可能引起的便秘情况外。

    下级分类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— Monensin sodium salt 22373-78-0 C36H61O11*Na
    Monensin sodium salt
    —— beta-Artemether 71963-77-4 C16H26O5
    beta-Artemether
    —— dihydroartemisinin 71939-50-9 C15H24O5
    dihydroartemisinin
    —— (-)-6-epi-artemisinin 63968-64-9 C15H22O5
    (-)-6-epi-artemisinin
    —— quinidine 42151-59-7 C20H24N2O2
    quinidine
    —— (1R,4S,5'S,6R,6'R,8R,12S,13S,20R,21R,24S)-6'-[(2S)-butan-2-yl]-21,24-dihydroxy-12-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one 70288-86-7 C48H74O14
    (1R,4S,5'S,6R,6'R,8R,12S,13S,20R,21R,24S)-6'-[(2S)-butan-2-yl]-21,24-dihydroxy-12-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one
    —— 4-oxo-4-[[(1R,5R,9R,10S,13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-yl]oxy]butanoic acid 88495-63-0 C19H28O8
    4-oxo-4-[[(1R,5R,9R,10S,13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-yl]oxy]butanoic acid
    —— (Dhqd)2aqn 176097-24-8 C54H56N4O6
    (Dhqd)2aqn
    —— Monensin A 17090-79-8 C36H62O11
    Monensin A
    —— Monensin 17090-79-8 C36H62O11
    Monensin
    —— lumefantrine 82186-77-4 C30H32Cl3NO
    lumefantrine
    —— Diminazene aceturate 908-54-3 C22H29N9O6
    Diminazene aceturate
    —— Succinyl dihydroartemisinin 182824-33-5 C19H28O8
    Succinyl dihydroartemisinin
    —— artemisinin 63968-64-9 C15H22O5
    artemisinin
    —— Pharmakon1600-01500524 62409-09-0 C20H26N2O6S
    Pharmakon1600-01500524
    —— sodium;(2R)-2-[(2R,5S,6R)-6-[(2S,3S,4S,6R)-6-[(3S,5S,7R,9S,10S,12R,15R)-3-[(2R,5R,6S)-5-ethyl-5-hydroxy-6-methyloxan-2-yl]-15-hydroxy-3,10,12-trimethyl-4,6,8-trioxadispiro[4.1.57.35]pentadec-13-en-9-yl]-3-hydroxy-4-methyl-5-oxooctan-2-yl]-5-methyloxan-2-yl]butanoic acid 55721-31-8 C42H70NaO11+
    sodium;(2R)-2-[(2R,5S,6R)-6-[(2S,3S,4S,6R)-6-[(3S,5S,7R,9S,10S,12R,15R)-3-[(2R,5R,6S)-5-ethyl-5-hydroxy-6-methyloxan-2-yl]-15-hydroxy-3,10,12-trimethyl-4,6,8-trioxadispiro[4.1.57.35]pentadec-13-en-9-yl]-3-hydroxy-4-methyl-5-oxooctan-2-yl]-5-methyloxan-2-yl]butanoic acid
    —— lasalocid sodium 25999-20-6 C34H53O8*Na
    lasalocid sodium
    —— lasalocid acid 25999-20-6 C34H56O6
    lasalocid acid
    —— salinomyicn 55721-31-8 C42H69O11*Na
    salinomyicn
    —— (S)-[(2R,5S)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-quinolin-4-ylmethanol 485-71-2 C19H22N2O
    (S)-[(2R,5S)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-quinolin-4-ylmethanol
    —— (1R,4S,5'S,6R,6'R,8R,10E,13S,14E,16E,20R,21R,24S)-6'-[(2S)-butan-2-yl]-21,24-dihydroxy-12-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one 70288-86-7 C48H74O14
    (1R,4S,5'S,6R,6'R,8R,10E,13S,14E,16E,20R,21R,24S)-6'-[(2S)-butan-2-yl]-21,24-dihydroxy-12-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one
    —— Dectomax 117704-25-3 C50H74O14
    Dectomax
    —— (1R,4S,6R,10E,14E,16E,21R)-6'-butan-2-yl-21,24-dihydroxy-12-[(2R,4S,6S)-5-[(2S,4S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one 70288-86-7 C48H74O14
    (1R,4S,6R,10E,14E,16E,21R)-6'-butan-2-yl-21,24-dihydroxy-12-[(2R,4S,6S)-5-[(2S,4S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one
    —— (1'R,2R,3S,4'S,6S,8'R,10'E,13'S,14'E,16'E,20'R,21'R,24'S)-2-cyclohexyl-21',24'-dihydroxy-12'-[(2R,4S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-3,11',13',22'-tetramethylspiro[2,3-dihydropyran-6,6'-3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene]-2'-one 117704-25-3 C50H74O14
    (1'R,2R,3S,4'S,6S,8'R,10'E,13'S,14'E,16'E,20'R,21'R,24'S)-2-cyclohexyl-21',24'-dihydroxy-12'-[(2R,4S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-3,11',13',22'-tetramethylspiro[2,3-dihydropyran-6,6'-3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene]-2'-one
    —— (2R)-2-[(2R,5S,6R)-6-[(1S,2S,3S,5R)-5-[(3S,5R,7S,9S,10S,12R,15R)-3-[(2R,5R,6S)-5-ethyl-5-hydroxy-6-methyl-tetrahydropyran-2-yl]-15-hydroxy-3,10,12-trimethyl-4,6,8-trioxadispiro[4.1.5^{7}.3^{5}]pentadec-13-en-9-yl]-2-hydroxy-1,3-dimethyl-4-oxo-heptyl]-5-methyl-tetrahydropyran-2-yl]butanoic acid 53003-10-4 C42H70O11
    (2R)-2-[(2R,5S,6R)-6-[(1S,2S,3S,5R)-5-[(3S,5R,7S,9S,10S,12R,15R)-3-[(2R,5R,6S)-5-ethyl-5-hydroxy-6-methyl-tetrahydropyran-2-yl]-15-hydroxy-3,10,12-trimethyl-4,6,8-trioxadispiro[4.1.5^{7}.3^{5}]pentadec-13-en-9-yl]-2-hydroxy-1,3-dimethyl-4-oxo-heptyl]-5-methyl-tetrahydropyran-2-yl]butanoic acid
    —— (R)-[(2R,5S)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(4-quinolinyl)methanol 118-10-5 C19H22N2O
    (R)-[(2R,5S)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(4-quinolinyl)methanol
    —— Hydroxystilbamidine 495-99-8 C16H16N4O
    Hydroxystilbamidine
    —— Morantel Tartrate 26155-31-7 C16H22N2O6S
    Morantel Tartrate
    —— N4-(6-chloro-2-methoxyacridin-9-yl)-N1,N1-diethylpentane-1,4-diamine dihydrochloride dihydrate 6151-30-0 C23H30ClN3O*2ClH*2H2O
    N4-(6-chloro-2-methoxyacridin-9-yl)-N1,N1-diethylpentane-1,4-diamine dihydrochloride dihydrate
    —— lycorine 476-28-8 C16H17NO4
    lycorine
    —— 2-epi-Ivermectin B1a 70288-86-7 C48H74O14
    2-epi-Ivermectin B1a
    —— (1R,4S,5'S,6R,6'S,8R,10E,12S,13S,14E,16E,20R,21R,24S)-6'-[(2S)-butan-2-yl]-21,24-dihydroxy-12-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one 70288-86-7 C48H74O14
    (1R,4S,5'S,6R,6'S,8R,10E,12S,13S,14E,16E,20R,21R,24S)-6'-[(2S)-butan-2-yl]-21,24-dihydroxy-12-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one
    —— Pharmakon1600-01505902 117704-25-3 C50H74O14
    Pharmakon1600-01505902
    —— (2R,3S)-2,3-dihydroxybutanedioic acid;1-methyl-2-[(E)-2-(3-methylthiophen-2-yl)ethenyl]-5,6-dihydro-4H-pyrimidine 26155-31-7 C16H22N2O6S
    (2R,3S)-2,3-dihydroxybutanedioic acid;1-methyl-2-[(E)-2-(3-methylthiophen-2-yl)ethenyl]-5,6-dihydro-4H-pyrimidine
    —— Pyrvinium embonate 3546-41-6 C75H70N6O6
    Pyrvinium embonate
    —— Antibiotic A-13001-C 61991-54-6 C47H83NO17
    Antibiotic A-13001-C
    —— Quinine hydrogen sulfate 804-63-7 C40H50N4O8S
    Quinine hydrogen sulfate
    —— Pentostam 16037-91-5 C12H37Na3O26Sb2
    Pentostam
    —— (1R,4S,5'S,6R,6'R,8R,12S,13S,20R,21R,24S)-6'-[(2R)-butan-2-yl]-21,24-dihydroxy-12-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one 70288-86-7 C48H74O14
    (1R,4S,5'S,6R,6'R,8R,12S,13S,20R,21R,24S)-6'-[(2R)-butan-2-yl]-21,24-dihydroxy-12-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one
    —— Maduramicin Ammonium Salt 84878-61-5 C47H83NO17
    Maduramicin Ammonium Salt
    —— Quinine hemisulfate monohydrate 6119-70-6 C40H52N4O9S
    Quinine hemisulfate monohydrate
    —— Pharmakon1600-01506152 551-92-8 C5H8N3O2+
    Pharmakon1600-01506152
    —— Pharmakon1600-01502032 129-46-4 C51H40N6NaO23S6+
    Pharmakon1600-01502032
    —— Dihydroqinghaosu, Dihydroartemisinin. 71939-50-9 C15H24O5
    Dihydroqinghaosu, Dihydroartemisinin.
    —— Pharmakon1600-01300027 70288-86-7 C48H74O14
    Pharmakon1600-01300027
    —— sodium;(2R)-2-[(2R,5S,6R)-6-[(2S,3S,4S,6R)-6-[(3S,5S,7R,9S,10S,12R,15R)-3-[(2R,5R,6S)-5-ethyl-5-hydroxy-6-methyloxan-2-yl]-15-hydroxy-3,10,12-trimethyl-4,6,8-trioxadispiro[4.1.57.35]pentadec-13-en-9-yl]-3-hydroxy-4-methyl-5-oxooctan-2-yl]-5-methyloxan-2-yl]butanoate;hydrate 55721-31-8 C42H71NaO12
    sodium;(2R)-2-[(2R,5S,6R)-6-[(2S,3S,4S,6R)-6-[(3S,5S,7R,9S,10S,12R,15R)-3-[(2R,5R,6S)-5-ethyl-5-hydroxy-6-methyloxan-2-yl]-15-hydroxy-3,10,12-trimethyl-4,6,8-trioxadispiro[4.1.57.35]pentadec-13-en-9-yl]-3-hydroxy-4-methyl-5-oxooctan-2-yl]-5-methyloxan-2-yl]butanoate;hydrate
    —— azanium;2-[(2R,3S,4S,5R,6R)-6-[(1R)-1-[(2S,5S,7S,8R,9S)-2-[(2R,5S)-5-[(2R,3S,5S)-3-[(2R,4S,5S,6S)-4,5-dimethoxy-6-methyloxan-2-yl]oxy-5-[(2S,3S,5R,6R)-6-hydroxy-3,5,6-trimethyloxan-2-yl]oxolan-2-yl]-5-methyloxolan-2-yl]-7-hydroxy-2,8-dimethyl-1,10-dioxaspiro[4.5]decan-9-yl]ethyl]-2-hydroxy-4,5-dimethoxy-3-methyloxan-2-yl]acetate 84878-61-5 C47H83NO17
    azanium;2-[(2R,3S,4S,5R,6R)-6-[(1R)-1-[(2S,5S,7S,8R,9S)-2-[(2R,5S)-5-[(2R,3S,5S)-3-[(2R,4S,5S,6S)-4,5-dimethoxy-6-methyloxan-2-yl]oxy-5-[(2S,3S,5R,6R)-6-hydroxy-3,5,6-trimethyloxan-2-yl]oxolan-2-yl]-5-methyloxolan-2-yl]-7-hydroxy-2,8-dimethyl-1,10-dioxaspiro[4.5]decan-9-yl]ethyl]-2-hydroxy-4,5-dimethoxy-3-methyloxan-2-yl]acetate
    —— (1S,4R,5R,8R,9R,10S,12R,13R)-10-methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecane 71963-77-4 C16H26O5
    (1S,4R,5R,8R,9R,10S,12R,13R)-10-methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecane
    —— 4-oxo-4-[[(1S,4S,8S,9R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-yl]oxy]butanoic acid 88495-63-0 C19H28O8
    4-oxo-4-[[(1S,4S,8S,9R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-yl]oxy]butanoic acid
    —— (6R,24S)-6'-butan-2-yl-21,24-dihydroxy-12-[5-(5-hydroxy-4-methoxy-6-methyloxan-2-yl)oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one 70288-86-7 C48H74O14
    (6R,24S)-6'-butan-2-yl-21,24-dihydroxy-12-[5-(5-hydroxy-4-methoxy-6-methyloxan-2-yl)oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one