驱肠虫药
驱肠虫药是用于清除寄生于人体肠道内的肠寄生虫（主要是蠕虫类）的一类药物，包括驱蛔虫药（如枸橼酸哌嗪）、驱蛲虫药（如扑蛲灵）、驱钩虫药（如丙硫咪唑）、驱鞭虫药（如酚嘧啶）和驱绦虫药（如鹤草芽）。其中，噻嘧啶、噻苯咪唑、丙硫咪唑和左旋咪唑等药物对多种肠虫感染均有效，因此被称为广谱驱肠虫药。
驱肠虫药的作用原理主要包括以下几点：① 作用于虫体的神经和肌肉系统，导致虫体肌肉发生强直性痉挛或弛缓性麻痹，使其失去吸附在肠壁的能力，随肠道蠕动而排出体外。大多数驱肠虫药物均具有此效用；② 影响酶活性，例如扑蛲灵可抑制蠕虫转运糖的酶系统，干扰其糖代谢过程；③ 消化虫体，如雷丸可以直接消化活的蠕虫组织。
| 中文名称 | 英文名称 | CAS号 | 化学式 | 结构式图片 |
|---|---|---|---|---|
| 鹤草酚 | agrimophol | 65792-05-4 | C26H34O8 |
|
| 阿苯达唑 | Albendazole | 54965-21-8 | C12H15N3O2S |
|
| 酒石酸甲噻嘧啶水合物 | trans-1,4,5,6-tetrahydro-1-methyl-2-[2-(3-methyl-thien-2-yl)-vinyl]-pyrimidine tartrate | 26155-31-7 | C4H6O6*C12H16N2S |
|
| 苯硫胍 | Febantel | 58306-30-2 | C20H22N4O6S |
|
| 羟萘酸苄酚宁 | bephenium 3-hydroxy-2-naphthoate | 3818-50-6 | C11H7O3*C17H22NO |
|
| 磷酸氢哌嗪单水合物 | H2piperazinedium hydrogenphosphate monohydrate | 18534-18-4 | C4H10N2*H2O*H3O4P |
|
| 磷酸哌嗪 | piperazine hydrogen phosphate | 1951-97-9 | C4H10N2*H3O4P |
|
| 盐酸左旋咪唑 | levamisole hydrochloride | 16595-80-5 | C11H13N2S*Cl |
|
| 盐酸四咪唑 | tetramisole hydrochloride | 5086-74-8 | C11H13N2S*Cl |
|
| 甲苯咪唑 | mebendazole | 31431-39-7 | C16H13N3O3 |
|
| 枸橼酸哌嗪一水合物 | Piperazine-1,4-diium 2-(carboxymethyl)-2-hydroxybutanedioate monohydrate | 41372-10-5 | C10H20N2O8 |
|
| 敌菌净 | diaveridine | 5355-16-8 | C13H16N4O2 |
|
| 己二酸哌嗪 | piperazine adipate | 142-88-1 | C4H10N2*C6H10O4 |
|
| 左旋咪唑 | Levamisole | 14769-73-4 | C11H12N2S |
|
| 山道年 | santonin | 481-06-1 | C15H18O3 |
|
| 奥苯达唑 | oxibendazole | 20559-55-1 | C12H15N3O3 |
|
| 奥吩达唑 | oxfendazole | 53716-50-0 | C15H13N3O3S |
|
| 奥克太尔 | Oxantel | 36531-26-7 | C13H16N2O |
|
| 四氯乙烯 | 1,1,2,2-tetrachloroethylene | 127-18-4 | C2Cl4 |
|
| 噻菌灵 | thiabendazole | 148-79-8 | C10H7N3S |
|
| 噻嘧啶 | pyrantel | 15686-83-6 | C11H14N2S |
|
| 哌嗪 | piperazine | 110-85-0 | C4H10N2 |
|
| 呋罗达唑 | 2-furan-2-yl-7-methyl-1(3),6-dihydro-imidazo[4,5-<i>f</i>]quinolin-9-one | 56119-96-1 | C15H11N3O2 |
|
| 双羟萘酸噻嘧啶 | pyrantel pamoate | 22204-24-6 | C11H14N2S*C23H16O6 |
|
| N-羟乙基哌嗪 | 1-(2-hydroxyethyl)piperazine | 103-76-4 | C6H14N2O |
|
| 4-己基间苯二酚 | 4-Hexylresorcinol | 136-77-6 | C12H18O2 |
|
| 1-溴-2-萘酚 | 1-bromo-2-naphthol | 573-97-7 | C10H7BrO |
|
| —— | toosendanin | 58812-37-6 | C30H38O11 |
|
| —— | Dimethyl-(2-phenoxyethyl)-(phenylmethyl)ammonium 3-hydroxy-2-naphthalenecarboxylic acid | 3818-50-6 | C28H30NO4+ |
|
| —— | Toosendanin | 58812-37-6 | C30H38O11 |
|
| —— | Morantel Tartrate | 26155-31-7 | C16H22N2O6S |
|
| —— | (2R,3S)-2,3-dihydroxybutanedioic acid;1-methyl-2-[(E)-2-(3-methylthiophen-2-yl)ethenyl]-5,6-dihydro-4H-pyrimidine | 26155-31-7 | C16H22N2O6S |
|
| —— | Pyrvinium embonate | 3546-41-6 | C75H70N6O6 |
|
| —— | Piperazine, 2-hydroxy-1,2,3-propanetricarboxylate (3:2), hydrate | 7140-78-5 | C26H50N4O24 |
|
| —— | Agrimophol | 65792-05-4 | C26H34O8 |
|
| —— | Santonin | 481-06-1 | C15H18O3 |
|
| —— | 3,5a,9-trimethyl-3a,4,5,5a-tetrahydro-3H,9bH-naphtho[1,2-b]furan-2,8-dione | 481-06-1 | C15H18O3 |
|
| —— | [4-Acetyloxy-6-(furan-3-yl)-12,16,19-trihydroxy-5,11,15-trimethyl-3-oxo-9,17-dioxahexacyclo[13.3.3.01,14.02,11.05,10.08,10]henicosan-21-yl] acetate | 58812-37-6 | C30H38O11 |
|
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