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    首页 分子通 按分子结构分类 有机化合物 苯丙烷和聚酮 大环内酰胺类

    大环内酰胺类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— tert-butyl N-[(10S,12S,16S)-16-amino-20-methyl-15,21-dioxo-8-oxa-14,20-diazatetracyclo[20.3.1.0<sup>2</sup>'<sup>7</sup>.0<sup>10</sup>'<sup>14</sup>]hexacosa-1(26),2,4,6,22,24-hexaen-12-yl]carbamate 1460301-52-3 C29H38N4O5
    tert-butyl N-[(10S,12S,16S)-16-amino-20-methyl-15,21-dioxo-8-oxa-14,20-diazatetracyclo[20.3.1.0<sup>2</sup>'<sup>7</sup>.0<sup>10</sup>'<sup>14</sup>]hexacosa-1(26),2,4,6,22,24-hexaen-12-yl]carbamate
    —— (3R,9R)-2,8-dioxo-1,7-diazacyclododecane-3,9-diamine 1174277-72-5 C10H20N4O2
    (3R,9R)-2,8-dioxo-1,7-diazacyclododecane-3,9-diamine
    —— sclerotiotide A 1232889-28-9 C22H34N4O4
    sclerotiotide A
    —— sclerotiotide B 1232889-32-5 C21H34N4O4
    sclerotiotide B
    —— (6S,7S,18S)-20-aza-6,10,12,18-tetramethyl-7-O-(2',6'-dideoxy-3'-C-methyl-β-D-ribo-hexopyranosyl)-cycloicosa-2,4,9,12,14-pentaen-1-one 312532-50-6 C30H47NO5
    (6S,7S,18S)-20-aza-6,10,12,18-tetramethyl-7-O-(2',6'-dideoxy-3'-C-methyl-β-D-ribo-hexopyranosyl)-cycloicosa-2,4,9,12,14-pentaen-1-one
    —— (6S,7S,18S)-(2E,4E,9E,12E,14E)-20-aza-6,10,12,18-tetramethyl-7-(trimethylsilyloxy)cycloicosa-2,4,9,12,14-pentaenone 343314-38-5 C26H43NO2Si
    (6S,7S,18S)-(2E,4E,9E,12E,14E)-20-aza-6,10,12,18-tetramethyl-7-(trimethylsilyloxy)cycloicosa-2,4,9,12,14-pentaenone
    —— 8-Fluoro-25-hydroxy-17-methyl-3,17,23,26-tetrazatetracyclo[16.7.2.05,10.023,27]heptacosa-1(25),5(10),6,8,26-pentaene-2,16,24-trione 1538554-41-4 C24H29FN4O4
    8-Fluoro-25-hydroxy-17-methyl-3,17,23,26-tetrazatetracyclo[16.7.2.05,10.023,27]heptacosa-1(25),5(10),6,8,26-pentaene-2,16,24-trione
    —— 8-Fluoro-25-hydroxy-11,17-dimethyl-3,11,17,23,26-pentazatetracyclo[16.7.2.05,10.023,27]heptacosa-1(25),5(10),6,8,26-pentaene-2,12,16,24-tetrone 1538554-46-9 C24H28FN5O5
    8-Fluoro-25-hydroxy-11,17-dimethyl-3,11,17,23,26-pentazatetracyclo[16.7.2.05,10.023,27]heptacosa-1(25),5(10),6,8,26-pentaene-2,12,16,24-tetrone
    —— tert-butyl N-[(12R,16S,18S)-12-{[2-(1-naphthyl)acetyl]amino}-8,13-dioxo-20-oxa-9,14-diazatetracyclo[19.3.1.0<sup>2</sup>'<sup>7</sup>.0<sup>14</sup>'<sup>18</sup>]pentacosa-1(25),2,4,6,21,23-hexaen-16-yl]carbamate 1460301-38-5 C39H42N4O6
    tert-butyl N-[(12R,16S,18S)-12-{[2-(1-naphthyl)acetyl]amino}-8,13-dioxo-20-oxa-9,14-diazatetracyclo[19.3.1.0<sup>2</sup>'<sup>7</sup>.0<sup>14</sup>'<sup>18</sup>]pentacosa-1(25),2,4,6,21,23-hexaen-16-yl]carbamate
    —— tert-butyl N-[(12R,16S,18S)-12-amino-8,13-dioxo-20-oxa-9,14-diazatetracyclo[19.3.1.0<sup>2</sup>'<sup>7</sup>.0<sup>14</sup>'<sup>18</sup>]pentacosa-1(25),2,4,6,21,23-hexaen-16-yl]carbamate 1460301-36-3 C27H34N4O5
    tert-butyl N-[(12R,16S,18S)-12-amino-8,13-dioxo-20-oxa-9,14-diazatetracyclo[19.3.1.0<sup>2</sup>'<sup>7</sup>.0<sup>14</sup>'<sup>18</sup>]pentacosa-1(25),2,4,6,21,23-hexaen-16-yl]carbamate
    —— hapalocyclamide 1359827-55-6 C25H26N6O4S2
    hapalocyclamide
    —— (13S,16R)-13-amino-16-methyl-18-oxa-8-thia-15-azatricyclo[17.3.1.0<sup>2,7</sup>]tricosa-1(23),2,4,6,19,21-hexaen-14-one 1460302-74-2 C21H26N2O2S
    (13S,16R)-13-amino-16-methyl-18-oxa-8-thia-15-azatricyclo[17.3.1.0<sup>2,7</sup>]tricosa-1(23),2,4,6,19,21-hexaen-14-one
    —— (9R)-6,7,10,11-tetrahydro-19-(phenylmethyl)-9-aminomethyl-9H,18H-5,21:12,17-dimethenodibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecine-18,20(19H)-dione 1224599-83-0 C33H30N4O3
    (9R)-6,7,10,11-tetrahydro-19-(phenylmethyl)-9-aminomethyl-9H,18H-5,21:12,17-dimethenodibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecine-18,20(19H)-dione
    —— 4-deoxymaytansinol 75340-67-9 C28H37ClN2O7
    4-deoxymaytansinol
    —— (+/-)-maysine 52978-28-6 C28H35ClN2O7
    (+/-)-maysine
    —— [(5'S,6'E,8'S,9'S,12'R,13'E,15'E)-5'-[tert-butyl(dimethyl)silyl]oxy-21'-chloro-12',20'-dimethoxy-2',6',8',16'-tetramethyl-3'-oxospiro[1,3-dithiane-2,11'-2-azabicyclo[16.3.1]docosa-1(21),6,13,15,18(22),19-hexaene]-9'-yl] carbamate 75349-68-7 C37H57ClN2O6S2Si
    [(5'S,6'E,8'S,9'S,12'R,13'E,15'E)-5'-[tert-butyl(dimethyl)silyl]oxy-21'-chloro-12',20'-dimethoxy-2',6',8',16'-tetramethyl-3'-oxospiro[1,3-dithiane-2,11'-2-azabicyclo[16.3.1]docosa-1(21),6,13,15,18(22),19-hexaene]-9'-yl] carbamate
    —— Maytansin 35846-53-8 C34H46ClN3O10
    Maytansin
    —— maytansine 9-O-methyl ether 64817-73-8 C35H48ClN3O10
    maytansine 9-O-methyl ether
    —— (5'S,6'E,8'S,9'S,12'R,13'E,15'E)-5'-[tert-butyl(dimethyl)silyl]oxy-21'-chloro-9'-hydroxy-12',20'-dimethoxy-2',6',8',16'-tetramethylspiro[1,3-dithiane-2,11'-2-azabicyclo[16.3.1]docosa-1(21),6,13,15,18(22),19-hexaene]-3'-one 75340-66-8 C36H56ClNO5S2Si
    (5'S,6'E,8'S,9'S,12'R,13'E,15'E)-5'-[tert-butyl(dimethyl)silyl]oxy-21'-chloro-9'-hydroxy-12',20'-dimethoxy-2',6',8',16'-tetramethylspiro[1,3-dithiane-2,11'-2-azabicyclo[16.3.1]docosa-1(21),6,13,15,18(22),19-hexaene]-3'-one
    —— 3-O-(tert-butyldimethylsilyl)-4,5-deoxymaytansinol 75349-69-8 C34H51ClN2O7Si
    3-O-(tert-butyldimethylsilyl)-4,5-deoxymaytansinol
    —— maytansine 35846-53-8 C34H46ClN3O10
    maytansine
    —— N-(4-chlorobenzyl)-2-((3R,8S,9S,11S)-8,9-dihydroxy-5,12-dioxo-3-phenyl-1-oxa-4-azacyclododecan-11-yl)acetamide 1589554-36-8 C25H29ClN2O6
    N-(4-chlorobenzyl)-2-((3R,8S,9S,11S)-8,9-dihydroxy-5,12-dioxo-3-phenyl-1-oxa-4-azacyclododecan-11-yl)acetamide
    —— 2-((3R,11S,E)-4-methyl-5,12-dioxo-3-phenyl-1-oxa-4-azacyclododec-8-en-11-yl)acetic acid 1589558-35-9 C19H23NO5
    2-((3R,11S,E)-4-methyl-5,12-dioxo-3-phenyl-1-oxa-4-azacyclododec-8-en-11-yl)acetic acid
    —— 2-((3R,11S,E)-5,12-dioxo-3-phenyl-1-oxa-4-azacyclododec-8-en-11-yl)-N-(1H-pyrazol-3-yl)acetamide 1589555-45-2 C21H24N4O4
    2-((3R,11S,E)-5,12-dioxo-3-phenyl-1-oxa-4-azacyclododec-8-en-11-yl)-N-(1H-pyrazol-3-yl)acetamide
    —— N<sup>2'</sup>-deacetyl-N<sup>2'</sup>-[4-methyl-4-(methyldithio)-1-oxopentyl]maytansine 796073-68-2 C39H56ClN3O10S2
    N<sup>2'</sup>-deacetyl-N<sup>2'</sup>-[4-methyl-4-(methyldithio)-1-oxopentyl]maytansine
    —— DM4 796073-69-3 C38H54ClN3O10S
    DM4
    —— ansamitocin P1 57103-69-2 C30H39ClN2O9
    ansamitocin P1
    —— maytansinol 57103-68-1 C28H37ClN2O8
    maytansinol
    —— N-deacetyl maytansine 77668-69-0 C32H44ClN3O9
    N-deacetyl maytansine
    —— N<sup>2'</sup>-deacetyl-N<sup>2'</sup>-[3-(methyldithio)-1-oxopropyl]maytansine 138148-68-2 C36H50ClN3O10S2
    N<sup>2'</sup>-deacetyl-N<sup>2'</sup>-[3-(methyldithio)-1-oxopropyl]maytansine
    —— ansamitocin P-3 66584-72-3 C32H43ClN2O9
    ansamitocin P-3
    —— (-)-maytansinol 57103-68-1 C28H37ClN2O8
    (-)-maytansinol
    —— 5,6-(4,5-dichlorobenzo)-3,8,11,13-tetraoxo-2,2,9,9-tetramethyl-12,12-diethyl-1,4,7,10-tetraazacyclotridecane 136668-03-6 C21H28Cl2N4O4
    5,6-(4,5-dichlorobenzo)-3,8,11,13-tetraoxo-2,2,9,9-tetramethyl-12,12-diethyl-1,4,7,10-tetraazacyclotridecane
    —— 2,9-dioxo-1,4,7,10-tetraaza-4,7-cyclotridecanediacetic acid 93031-56-2 C13H22N4O6
    2,9-dioxo-1,4,7,10-tetraaza-4,7-cyclotridecanediacetic acid
    —— (2R,6R,14aR,16aS,Z)-N-(cyclopropylsulfonyl)-6-(2-(3,3-difluoropiperidin-1-yl)-2-oxoethyl)-2-(2-(4-isopropylthiazol-2-yl)-7-methoxy-8-methylquinolin-4-yloxy)-5,16-dioxo-1,2,3,5,6,7,8,9,10,11,13a,14,14a,15,16,16a-hexadecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecine-14a-carboxamide sodium salt —— C45H55F2N6O8S2*Na
    (2R,6R,14aR,16aS,Z)-N-(cyclopropylsulfonyl)-6-(2-(3,3-difluoropiperidin-1-yl)-2-oxoethyl)-2-(2-(4-isopropylthiazol-2-yl)-7-methoxy-8-methylquinolin-4-yloxy)-5,16-dioxo-1,2,3,5,6,7,8,9,10,11,13a,14,14a,15,16,16a-hexadecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecine-14a-carboxamide sodium salt
    —— (2R,6R,14aR,16aS,Z)-N-(cyclopropylsulfonyl)-6-(2-(3,3-difluoropiperidin-1-yl)-2-oxoethyl)-2-(2-(4-isopropylthiazol-2-yl)-7-methoxy-8-methylquinolin-4-yloxy)-5,16-dioxo-1,2,3,5,6,7,8,9,10,11,13a,14,14a,15,16,16a-hexadecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecine-14a-carboxamide 1229626-28-1 C45H56F2N6O8S2
    (2R,6R,14aR,16aS,Z)-N-(cyclopropylsulfonyl)-6-(2-(3,3-difluoropiperidin-1-yl)-2-oxoethyl)-2-(2-(4-isopropylthiazol-2-yl)-7-methoxy-8-methylquinolin-4-yloxy)-5,16-dioxo-1,2,3,5,6,7,8,9,10,11,13a,14,14a,15,16,16a-hexadecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecine-14a-carboxamide
    —— 3-(25-O-desacetyl-25-O-carbonyl-cyclic-21,23-(1-methylethylidene acetal)-3-morpholino-rifamycin S)-3H-imidazole 869187-60-0 C46H56N4O13
    3-(25-O-desacetyl-25-O-carbonyl-cyclic-21,23-(1-methylethylidene acetal)-3-morpholino-rifamycin S)-3H-imidazole
    —— (E)-azacyclohexadec-6-en-2-one 1415549-46-0 C15H27NO
    (E)-azacyclohexadec-6-en-2-one
    —— 20,20-dimethyl-5-(2,2,2-trifluoroethoxy)-14-oxa-2,6,8,18,22,31-hexazatetracyclo[22.2.2.210,13.13,7]hentriaconta-1(26),3,5,7(31),10(30),11,13(29),24,27-nonaen-23-one 1430195-57-5 C28H33F3N6O3
    20,20-dimethyl-5-(2,2,2-trifluoroethoxy)-14-oxa-2,6,8,18,22,31-hexazatetracyclo[22.2.2.210,13.13,7]hentriaconta-1(26),3,5,7(31),10(30),11,13(29),24,27-nonaen-23-one
    —— 19-(4-morpholinylphenyl)-GA 1427296-94-3 C39H51N3O10
    19-(4-morpholinylphenyl)-GA
    —— (4E,6Z,8S,9E,11S,12R,13R,14S,16R)-19-(azetidin-1-yl)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-11-sulfanyl-2-azabicyclo[16.3.1]docosa-1(21),4,6,9,18-pentaene-3,20,22-trione 155630-43-6 C30H42N2O6S
    (4E,6Z,8S,9E,11S,12R,13R,14S,16R)-19-(azetidin-1-yl)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-11-sulfanyl-2-azabicyclo[16.3.1]docosa-1(21),4,6,9,18-pentaene-3,20,22-trione
    —— 17-Azetidinyl-7-decarbamoyl-17-demethoxygeldanamycin 155630-41-4 C30H42N2O7
    17-Azetidinyl-7-decarbamoyl-17-demethoxygeldanamycin
    —— 17-(4-chloro-3-pyridinmethanamine)-17-demethoxygeldanamycin 1474021-75-4 C34H43ClN4O8
    17-(4-chloro-3-pyridinmethanamine)-17-demethoxygeldanamycin
    —— 17-methylamino-17-demethoxygeldanamycin 71952-93-7 C29H41N3O8
    17-methylamino-17-demethoxygeldanamycin
    —— (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-19-(allylamino)-21-(furan-2-yl)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate 1427297-03-7 C35H45N3O9
    (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-19-(allylamino)-21-(furan-2-yl)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
    —— 19-vinylgeldanamycin 1427296-90-9 C31H42N2O9
    19-vinylgeldanamycin
    —— 17-Azetidinyl-7-thioureido-7-decarbamoyl-17-demethoxygeldanamycin 169564-31-2 C31H44N4O6S
    17-Azetidinyl-7-thioureido-7-decarbamoyl-17-demethoxygeldanamycin
    —— 17-(4-bromobenzylamino)-17-demethoxygeldanamycin 1622011-47-5 C35H44BrN3O8
    17-(4-bromobenzylamino)-17-demethoxygeldanamycin
    —— 17-(4-sulfamoylbenzylamino)-17-demethoxygeldanamycin 1622011-60-2 C35H46N4O10S
    17-(4-sulfamoylbenzylamino)-17-demethoxygeldanamycin
    —— 17-(3,4-dimethoxybenzylamino)-17-demethoxygeldanamycin 1622011-53-3 C37H49N3O10
    17-(3,4-dimethoxybenzylamino)-17-demethoxygeldanamycin