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    首页 分子通 按分子结构分类 有机化合物 苯丙烷和聚酮 大环内酰胺类

    大环内酰胺类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— (10R,14S)-14-[4-(6-bromo-3-chloro-2-fluorophenyl)-6-oxo-2,3-dihydropyridin-1-yl]-3,5-difluoro-10-methyl-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaen-9-one —— C29H24BrClF3N3O2
    (10R,14S)-14-[4-(6-bromo-3-chloro-2-fluorophenyl)-6-oxo-2,3-dihydropyridin-1-yl]-3,5-difluoro-10-methyl-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaen-9-one
    —— methyl N-[(10R,14S)-14-[4-(6-bromo-3-chloro-2-fluorophenyl)-6-oxopyridazin-1-yl]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaen-5-yl]carbamate —— C30H26BrClFN5O4
    methyl N-[(10R,14S)-14-[4-(6-bromo-3-chloro-2-fluorophenyl)-6-oxopyridazin-1-yl]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaen-5-yl]carbamate
    —— methyl N-[(9R,13S)-13-[4-(3-chloro-2,6-difluorophenyl)-6-oxo-2,3-dihydropyridin-1-yl]-9-methyl-8-oxo-2,3,7,15-tetrazatricyclo[12.3.1.02,6]octadeca-1(18),4,6,14,16-pentaen-4-yl]carbamate —— C28H27ClF2N6O4
    methyl N-[(9R,13S)-13-[4-(3-chloro-2,6-difluorophenyl)-6-oxo-2,3-dihydropyridin-1-yl]-9-methyl-8-oxo-2,3,7,15-tetrazatricyclo[12.3.1.02,6]octadeca-1(18),4,6,14,16-pentaen-4-yl]carbamate
    —— methyl N-[(10R,14S)-14-[4-(3-chloro-2-methylphenyl)-6-oxo-2,3-dihydropyridin-1-yl]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaen-5-yl]carbamate —— C32H33ClN4O4
    methyl N-[(10R,14S)-14-[4-(3-chloro-2-methylphenyl)-6-oxo-2,3-dihydropyridin-1-yl]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaen-5-yl]carbamate
    —— (10R,14S)-14-[4-(6-bromo-3-chloro-2-fluorophenyl)-6-oxo-1,2,3,6-tetrahydropyridin-1-yl]-10-methyl-9-oxo-8-azatricyclo[13.3.1.0<sup>2</sup>'<sup>7</sup>]nonadeca-1(19),2,4,6,15,17-hexaene-4-carboxylic acid —— C31H27BrClFN2O4
    (10R,14S)-14-[4-(6-bromo-3-chloro-2-fluorophenyl)-6-oxo-1,2,3,6-tetrahydropyridin-1-yl]-10-methyl-9-oxo-8-azatricyclo[13.3.1.0<sup>2</sup>'<sup>7</sup>]nonadeca-1(19),2,4,6,15,17-hexaene-4-carboxylic acid
    —— (10R,14S)-14-[4-(3-chloro-2,6-difluorophenyl)-6-oxo-2,3-dihydropyridin-1-yl]-10,17-dimethyl-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-9-one —— C28H27ClF2N4O2
    (10R,14S)-14-[4-(3-chloro-2,6-difluorophenyl)-6-oxo-2,3-dihydropyridin-1-yl]-10,17-dimethyl-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2,4,6,15(18)-pentaen-9-one
    —— N-[(10R,14S)-14-[4-(3-chloro-2,6-difluorophenyl)-6-oxo-2,3-dihydropyridin-1-yl]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaen-5-yl]acetamide —— C31H29ClF2N4O3
    N-[(10R,14S)-14-[4-(3-chloro-2,6-difluorophenyl)-6-oxo-2,3-dihydropyridin-1-yl]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaen-5-yl]acetamide
    —— US9951071, Example 28 —— C30H26BrClFN3O4
    US9951071, Example 28
    —— 4-chloro-2-[1-[(10R,14S)-4,5-difluoro-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2,4,6,15,17-hexaen-14-yl]-6-oxo-2,3-dihydropyridin-4-yl]-3-fluorobenzonitrile —— C30H24ClF3N4O2
    4-chloro-2-[1-[(10R,14S)-4,5-difluoro-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2,4,6,15,17-hexaen-14-yl]-6-oxo-2,3-dihydropyridin-4-yl]-3-fluorobenzonitrile
    —— methyl N-[(10R,14S)-14-[4-(3-chloro-2,6-difluorophenyl)-5-methyl-6-oxo-1,2,3,6-tetrahydropyridin-1-yl]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.0<sup>2</sup>'<sup>7</sup>]nonadeca-1(19),2,4,6,15,17-hexaen-5-yl]carbamate —— C32H31ClF2N4O4
    methyl N-[(10R,14S)-14-[4-(3-chloro-2,6-difluorophenyl)-5-methyl-6-oxo-1,2,3,6-tetrahydropyridin-1-yl]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.0<sup>2</sup>'<sup>7</sup>]nonadeca-1(19),2,4,6,15,17-hexaen-5-yl]carbamate
    —— (Z)-3-[(10R,14S)-5-amino-14-[4-(3-chloro-2,6-difluorophenyl)-6-oxo-2,3-dihydropyridin-1-yl]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaen-4-yl]prop-2-enoic acid —— C32H29ClF2N4O4
    (Z)-3-[(10R,14S)-5-amino-14-[4-(3-chloro-2,6-difluorophenyl)-6-oxo-2,3-dihydropyridin-1-yl]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaen-4-yl]prop-2-enoic acid
    —— (10R,14S)-14-[4-(3-chloro-2,6-difluorophenyl)-6-oxo-2,3-dihydropyridin-1-yl]-10-methyl-5-(pyridazin-3-ylamino)-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaen-9-one —— C33H29ClF2N6O2
    (10R,14S)-14-[4-(3-chloro-2,6-difluorophenyl)-6-oxo-2,3-dihydropyridin-1-yl]-10-methyl-5-(pyridazin-3-ylamino)-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaen-9-one
    —— (10R,14S)-14-[4-(3-chloro-2-fluorophenyl)-6-oxo-1,2,3,6-tetrahydropyridin-1-yl]-10-methyl-9-oxo-8-azatricyclo[13.3.1.0<sup>2</sup>'<sup>7</sup>]nonadeca-1(18),2,4,6,15(19),16-hexaene-4-carboxylate —— C32H30ClFN2O4
    (10R,14S)-14-[4-(3-chloro-2-fluorophenyl)-6-oxo-1,2,3,6-tetrahydropyridin-1-yl]-10-methyl-9-oxo-8-azatricyclo[13.3.1.0<sup>2</sup>'<sup>7</sup>]nonadeca-1(18),2,4,6,15(19),16-hexaene-4-carboxylate
    —— (10R,14S)-14-[4-(3-chloro-2-fluorophenyl)-2-oxopyridin-1-yl]-3,5-difluoro-10-methyl-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaen-9-one —— C29H23ClF3N3O2
    (10R,14S)-14-[4-(3-chloro-2-fluorophenyl)-2-oxopyridin-1-yl]-3,5-difluoro-10-methyl-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaen-9-one
    —— methyl (10R,14S)-14-[4-(6-acetyl-3-chloro-2-fluorophenyl)-6-oxo-1,2,3,6-tetrahydropyridin-1-yl]-10-methyl-9-oxo-8-azatricyclo[13.3.1.0<sup>2</sup>'<sup>7</sup>]nonadeca-1(18),2,4,6,15(19),16-hexaene-4-carboxylate —— C34H32ClFN2O5
    methyl (10R,14S)-14-[4-(6-acetyl-3-chloro-2-fluorophenyl)-6-oxo-1,2,3,6-tetrahydropyridin-1-yl]-10-methyl-9-oxo-8-azatricyclo[13.3.1.0<sup>2</sup>'<sup>7</sup>]nonadeca-1(18),2,4,6,15(19),16-hexaene-4-carboxylate
    —— 2-[(2-methylpropan-2-yl)oxy]ethyl N-[(10R,14S)-14-[4-(3-chloro-2,6-difluorophenyl)-6-oxo-2,3-dihydropyridin-1-yl]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaen-5-yl]carbamate —— C36H39ClF2N4O5
    2-[(2-methylpropan-2-yl)oxy]ethyl N-[(10R,14S)-14-[4-(3-chloro-2,6-difluorophenyl)-6-oxo-2,3-dihydropyridin-1-yl]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaen-5-yl]carbamate
    —— (9R,13S)-13-[4-(3-chloro-2,6-difluorophenyl)-6-oxo-2,3-dihydropyridin-1-yl]-9-methyl-8-oxo-2,3,7,15-tetrazatricyclo[12.3.1.02,6]octadeca-1(18),4,6,14,16-pentaene-4-carboxylic acid —— C27H24ClF2N5O4
    (9R,13S)-13-[4-(3-chloro-2,6-difluorophenyl)-6-oxo-2,3-dihydropyridin-1-yl]-9-methyl-8-oxo-2,3,7,15-tetrazatricyclo[12.3.1.02,6]octadeca-1(18),4,6,14,16-pentaene-4-carboxylic acid
    —— methyl N-[(10R,14S)-17-chloro-14-[4-(3-chloro-2,6-difluorophenyl)-6-oxo-2,3-dihydropyridin-1-yl]-10-methyl-9-oxo-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2(7),3,5,15(18)-pentaen-5-yl]carbamate —— C29H27Cl2F2N5O4
    methyl N-[(10R,14S)-17-chloro-14-[4-(3-chloro-2,6-difluorophenyl)-6-oxo-2,3-dihydropyridin-1-yl]-10-methyl-9-oxo-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2(7),3,5,15(18)-pentaen-5-yl]carbamate
    —— 2-hydroxyethyl N-[(10R,14S)-14-[4-(3-chloro-2,6-difluorophenyl)-6-oxo-2,3-dihydropyridin-1-yl]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaen-5-yl]carbamate —— C32H31ClF2N4O5
    2-hydroxyethyl N-[(10R,14S)-14-[4-(3-chloro-2,6-difluorophenyl)-6-oxo-2,3-dihydropyridin-1-yl]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaen-5-yl]carbamate
    —— methyl N-[(10R,14S)-14-[4-(3-chloro-2-methoxyphenyl)-6-oxo-1,2,3,6-tetrahydropyridin-1-yl]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.0<sup>2</sup>'<sup>7</sup>]nonadeca-1(18),2,4,6,15(19),16-hexaen-5-yl]carbamate —— C32H33ClN4O5
    methyl N-[(10R,14S)-14-[4-(3-chloro-2-methoxyphenyl)-6-oxo-1,2,3,6-tetrahydropyridin-1-yl]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.0<sup>2</sup>'<sup>7</sup>]nonadeca-1(18),2,4,6,15(19),16-hexaen-5-yl]carbamate
    —— (10R,14S)-14-[4-(3-chloro-2,6-difluorophenyl)-6-oxo-2,3-dihydropyridin-1-yl]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2,4,6,15,17-hexaene-3-carboxylic acid —— C30H26ClF2N3O4
    (10R,14S)-14-[4-(3-chloro-2,6-difluorophenyl)-6-oxo-2,3-dihydropyridin-1-yl]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2,4,6,15,17-hexaene-3-carboxylic acid
    —— methyl N-[(10R,14S)-14-[4-(3-bromo-2,6-difluorophenyl)-6-oxo-1,2,3,6-tetrahydropyridin-1-yl]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.0<sup>2</sup>'<sup>7</sup>]nonadeca-1(19),2,4,6,15,17-hexaen-5-yl]carbamate —— C31H29BrF2N4O4
    methyl N-[(10R,14S)-14-[4-(3-bromo-2,6-difluorophenyl)-6-oxo-1,2,3,6-tetrahydropyridin-1-yl]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.0<sup>2</sup>'<sup>7</sup>]nonadeca-1(19),2,4,6,15,17-hexaen-5-yl]carbamate
    —— (10R,14S)-14-[4-(3-chloro-6-cyclopropyl-2-fluorophenyl)-6-oxo-2,3-dihydropyridin-1-yl]-10-methyl-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2,4,6,15,17-hexaen-9-one —— C32H31ClFN3O2
    (10R,14S)-14-[4-(3-chloro-6-cyclopropyl-2-fluorophenyl)-6-oxo-2,3-dihydropyridin-1-yl]-10-methyl-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2,4,6,15,17-hexaen-9-one
    —— methyl N-[(10R,14S)-10-methyl-9-oxo-14-(6-oxo-4-piperidin-4-yl-2,3-dihydropyridin-1-yl)-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaen-5-yl]carbamate —— C30H37N5O4
    methyl N-[(10R,14S)-10-methyl-9-oxo-14-(6-oxo-4-piperidin-4-yl-2,3-dihydropyridin-1-yl)-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaen-5-yl]carbamate
    —— (14S)-14-[4-(3-chloro-2-fluorophenyl)-6-oxo-2,3-dihydropyridin-1-yl]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaene-5-carboxamide —— C30H28ClFN4O3
    (14S)-14-[4-(3-chloro-2-fluorophenyl)-6-oxo-2,3-dihydropyridin-1-yl]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaene-5-carboxamide
    —— methyl N-[(10R,14S)-14-[4-(6-acetyl-3-chloro-2-fluorophenyl)-6-oxo-1,2,3,6-tetrahydropyridin-1-yl]-10-methyl-9-oxo-8-azatricyclo[13.3.1.0<sup>2</sup>'<sup>7</sup>]nonadeca-1(18),2,4,6,15(19),16-hexaen-5-yl]carbamate —— C34H33ClFN3O5
    methyl N-[(10R,14S)-14-[4-(6-acetyl-3-chloro-2-fluorophenyl)-6-oxo-1,2,3,6-tetrahydropyridin-1-yl]-10-methyl-9-oxo-8-azatricyclo[13.3.1.0<sup>2</sup>'<sup>7</sup>]nonadeca-1(18),2,4,6,15(19),16-hexaen-5-yl]carbamate
    —— methyl N-[(10R,14S)-14-[4-(4-methoxyphenyl)-6-oxo-1,2,3,6-tetrahydropyridin-1-yl]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.0<sup>2</sup>'<sup>7</sup>]nonadeca-1(18),2,4,6,15(19),16-hexaen-5-yl]carbamate —— C32H34N4O5
    methyl N-[(10R,14S)-14-[4-(4-methoxyphenyl)-6-oxo-1,2,3,6-tetrahydropyridin-1-yl]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.0<sup>2</sup>'<sup>7</sup>]nonadeca-1(18),2,4,6,15(19),16-hexaen-5-yl]carbamate
    —— (10R,14S)-14-[4-(3-chloro-2,6-difluorophenyl)-6-oxo-2,3-dihydropyridin-1-yl]-10-methyl-5-(pyrazin-2-ylamino)-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaen-9-one —— C33H29ClF2N6O2
    (10R,14S)-14-[4-(3-chloro-2,6-difluorophenyl)-6-oxo-2,3-dihydropyridin-1-yl]-10-methyl-5-(pyrazin-2-ylamino)-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaen-9-one
    —— (10R,14S)-14-{4-[3-chloro-2-fluoro-6-(1H-1,2,3,4-tetrazol-1-yl)phenyl]-6-oxo-1,2,3,6-tetrahydropyridin-1-yl}-4,5-difluoro-10-methyl-8,16-diazatricyclo[13.3.1.0<sup>2</sup>'<sup>7</sup>]nonadeca-1(19),2(7),3,5,15,17-hexaen-9-one trifluoroacetic acid —— C30H25ClF3N7O2
    (10R,14S)-14-{4-[3-chloro-2-fluoro-6-(1H-1,2,3,4-tetrazol-1-yl)phenyl]-6-oxo-1,2,3,6-tetrahydropyridin-1-yl}-4,5-difluoro-10-methyl-8,16-diazatricyclo[13.3.1.0<sup>2</sup>'<sup>7</sup>]nonadeca-1(19),2(7),3,5,15,17-hexaen-9-one trifluoroacetic acid
    —— methyl (10R,14S)-14-[4-(3-chloro-6-cyano-2-fluorophenyl)-6-oxo-1,2,3,6-tetrahydropyridin-1-yl]-10-methyl-9-oxo-8-azatricyclo[13.3.1.0<sup>2</sup>'<sup>7</sup>]nonadeca-1(18),2,4,6,15(19),16-hexaene-4-carboxylate —— C33H29ClFN3O4
    methyl (10R,14S)-14-[4-(3-chloro-6-cyano-2-fluorophenyl)-6-oxo-1,2,3,6-tetrahydropyridin-1-yl]-10-methyl-9-oxo-8-azatricyclo[13.3.1.0<sup>2</sup>'<sup>7</sup>]nonadeca-1(18),2,4,6,15(19),16-hexaene-4-carboxylate
    —— N-[(10R,14S)-14-[4-(3-chloro-2,6-difluorophenyl)-6-oxo-2,3-dihydropyridin-1-yl]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaen-5-yl]methanesulfonamide —— C30H29ClF2N4O4S
    N-[(10R,14S)-14-[4-(3-chloro-2,6-difluorophenyl)-6-oxo-2,3-dihydropyridin-1-yl]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaen-5-yl]methanesulfonamide
    —— methyl N-[(10R,11E,14S)-14-[4-(3-chloro-2,6-difluorophenyl)-6-oxo-2,3-dihydropyridin-1-yl]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,11,15,17-heptaen-5-yl]carbamate —— C31H27ClF2N4O4
    methyl N-[(10R,11E,14S)-14-[4-(3-chloro-2,6-difluorophenyl)-6-oxo-2,3-dihydropyridin-1-yl]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,11,15,17-heptaen-5-yl]carbamate
    —— (14R,18S)-18-[4-(3-chloro-2,6-difluorophenyl)-6-oxo-2,3-dihydropyridin-1-yl]-14-methyl-8,12,20-triazatetracyclo[17.3.1.02,11.04,9]tricosa-1(23),2(11),3,9,19,21-hexaene-7,13-dione —— C32H29ClF2N4O3
    (14R,18S)-18-[4-(3-chloro-2,6-difluorophenyl)-6-oxo-2,3-dihydropyridin-1-yl]-14-methyl-8,12,20-triazatetracyclo[17.3.1.02,11.04,9]tricosa-1(23),2(11),3,9,19,21-hexaene-7,13-dione
    —— methyl N-[(10R,14S)-10-methyl-14-[4-(3-methylimidazol-4-yl)-6-oxo-2,3-dihydropyridin-1-yl]-9-oxo-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaen-5-yl]carbamate —— C29H32N6O4
    methyl N-[(10R,14S)-10-methyl-14-[4-(3-methylimidazol-4-yl)-6-oxo-2,3-dihydropyridin-1-yl]-9-oxo-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaen-5-yl]carbamate
    —— (10R,14S)-14-[4-(3-chloro-2,6-difluorophenyl)-2-oxopyridin-1-yl]-3-fluoro-10-methyl-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaen-9-one —— C29H23ClF3N3O2
    (10R,14S)-14-[4-(3-chloro-2,6-difluorophenyl)-2-oxopyridin-1-yl]-3-fluoro-10-methyl-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaen-9-one
    —— (10R,14S)-14-[4-[3-chloro-2-fluoro-6-(1H-pyrazol-4-yl)phenyl]-6-oxo-2,3-dihydropyridin-1-yl]-10-methyl-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2,4,6,15,17-hexaen-9-one —— C32H29ClFN5O2
    (10R,14S)-14-[4-[3-chloro-2-fluoro-6-(1H-pyrazol-4-yl)phenyl]-6-oxo-2,3-dihydropyridin-1-yl]-10-methyl-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2,4,6,15,17-hexaen-9-one
    —— (10R,14S)-14-[4-(3-chloro-2-fluoro-6-pyridin-3-ylphenyl)-6-oxo-2,3-dihydropyridin-1-yl]-10-methyl-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2,4,6,15,17-hexaen-9-one —— C34H30ClFN4O2
    (10R,14S)-14-[4-(3-chloro-2-fluoro-6-pyridin-3-ylphenyl)-6-oxo-2,3-dihydropyridin-1-yl]-10-methyl-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2,4,6,15,17-hexaen-9-one
    —— methyl N-[(10R,14S)-14-[4-(2,3-dimethylphenyl)-6-oxo-1,2,3,6-tetrahydropyridin-1-yl]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.0<sup>2</sup>'<sup>7</sup>]nonadeca-1(18),2,4,6,15(19),16-hexaen-5-yl]carbamate —— C33H36N4O4
    methyl N-[(10R,14S)-14-[4-(2,3-dimethylphenyl)-6-oxo-1,2,3,6-tetrahydropyridin-1-yl]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.0<sup>2</sup>'<sup>7</sup>]nonadeca-1(18),2,4,6,15(19),16-hexaen-5-yl]carbamate
    —— (10R,14S)-14-[4-(6-bromo-3-chloro-2-fluorophenyl)-6-oxo-2,3-dihydropyridin-1-yl]-3,4-difluoro-10-methyl-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaen-9-one —— C29H24BrClF3N3O2
    (10R,14S)-14-[4-(6-bromo-3-chloro-2-fluorophenyl)-6-oxo-2,3-dihydropyridin-1-yl]-3,4-difluoro-10-methyl-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaen-9-one
    —— methyl N-[(10R,14S)-14-[4-(2-fluoro-3-methoxyphenyl)-6-oxo-2,3-dihydropyridin-1-yl]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaen-5-yl]carbamate —— C32H33FN4O5
    methyl N-[(10R,14S)-14-[4-(2-fluoro-3-methoxyphenyl)-6-oxo-2,3-dihydropyridin-1-yl]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaen-5-yl]carbamate
    —— methyl N-[(10R,14S)-14-[4-[3-chloro-2-fluoro-6-(2H-triazol-4-yl)phenyl]-6-oxo-2,3-dihydropyridin-1-yl]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaen-5-yl]carbamate —— C33H31ClFN7O4
    methyl N-[(10R,14S)-14-[4-[3-chloro-2-fluoro-6-(2H-triazol-4-yl)phenyl]-6-oxo-2,3-dihydropyridin-1-yl]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaen-5-yl]carbamate
    —— methyl N-[(10R,14S)-14-[4-(2-chloropyridin-4-yl)-6-oxo-2,3-dihydropyridin-1-yl]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaen-5-yl]carbamate —— C30H30ClN5O4
    methyl N-[(10R,14S)-14-[4-(2-chloropyridin-4-yl)-6-oxo-2,3-dihydropyridin-1-yl]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaen-5-yl]carbamate
    —— methyl (10R,14S)-14-[4-(3,6-dicyano-2-fluorophenyl)-6-oxo-1,2,3,6-tetrahydropyridin-1-yl]-10-methyl-9-oxo-8-azatricyclo[13.3.1.0<sup>2</sup>'<sup>7</sup>]nonadeca-1(18),2,4,6,15(19),16-hexaene-4-carboxylate —— C34H29FN4O4
    methyl (10R,14S)-14-[4-(3,6-dicyano-2-fluorophenyl)-6-oxo-1,2,3,6-tetrahydropyridin-1-yl]-10-methyl-9-oxo-8-azatricyclo[13.3.1.0<sup>2</sup>'<sup>7</sup>]nonadeca-1(18),2,4,6,15(19),16-hexaene-4-carboxylate
    —— methyl N-[(15S)-15-[4-(3-chloro-2,6-difluorophenyl)-6-oxo-2,3-dihydropyridin-1-yl]-8-oxo-9,17-diazatricyclo[14.3.1.02,7]icosa-1(20),2(7),3,5,16,18-hexaen-5-yl]carbamate —— C31H29ClF2N4O4
    methyl N-[(15S)-15-[4-(3-chloro-2,6-difluorophenyl)-6-oxo-2,3-dihydropyridin-1-yl]-8-oxo-9,17-diazatricyclo[14.3.1.02,7]icosa-1(20),2(7),3,5,16,18-hexaen-5-yl]carbamate
    —— US9951071, Example 180 —— C31H28ClF3N4O4
    US9951071, Example 180
    —— (10R,14S)-14-[4-(3-chloro-2,6-difluorophenyl)-6-oxo-1,2,3,6-tetrahydropyridin-1-yl]-10-methyl-5-{[(3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]amino}-8,16-diazatricyclo [13.3.1.0<sup>2</sup>'<sup>7</sup>]nonadeca-1(19),2,4,6,15,17-hexaen-9-one —— C35H37ClF2N4O7
    (10R,14S)-14-[4-(3-chloro-2,6-difluorophenyl)-6-oxo-1,2,3,6-tetrahydropyridin-1-yl]-10-methyl-5-{[(3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]amino}-8,16-diazatricyclo [13.3.1.0<sup>2</sup>'<sup>7</sup>]nonadeca-1(19),2,4,6,15,17-hexaen-9-one
    —— methyl N-[(10R,14S)-14-[4-(3-chloro-6-ethynyl-2-fluorophenyl)-6-oxo-1,2,3,6-tetrahydropyridin-1-yl]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.0<sup>2</sup>'<sup>7</sup>]nonadeca-1(19),2(7),3,5,15,17-hexaen-5-yl]carbamate —— C33H30ClFN4O4
    methyl N-[(10R,14S)-14-[4-(3-chloro-6-ethynyl-2-fluorophenyl)-6-oxo-1,2,3,6-tetrahydropyridin-1-yl]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.0<sup>2</sup>'<sup>7</sup>]nonadeca-1(19),2(7),3,5,15,17-hexaen-5-yl]carbamate
    —— 2-[(10R,14S)-14-[4-(3-chloro-2,6-difluorophenyl)-6-oxo-2,3-dihydropyridin-1-yl]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaen-5-yl]guanidine —— C30H29ClF2N6O2
    2-[(10R,14S)-14-[4-(3-chloro-2,6-difluorophenyl)-6-oxo-2,3-dihydropyridin-1-yl]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaen-5-yl]guanidine
    —— (10R,14S)-14-[4-(3-chloro-2,6-difluorophenyl)-6-oxo-2,3-dihydropyridin-1-yl]-5-[[5-(furan-2-yl)-1,3,4-oxadiazol-2-yl]amino]-10-methyl-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaen-9-one —— C35H29ClF2N6O4
    (10R,14S)-14-[4-(3-chloro-2,6-difluorophenyl)-6-oxo-2,3-dihydropyridin-1-yl]-5-[[5-(furan-2-yl)-1,3,4-oxadiazol-2-yl]amino]-10-methyl-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaen-9-one
    —— methyl N-[(10R,14S)-14-(4-cyclohexyl-6-oxo-2,3-dihydropyridin-1-yl)-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaen-5-yl]carbamate —— C31H38N4O4
    methyl N-[(10R,14S)-14-(4-cyclohexyl-6-oxo-2,3-dihydropyridin-1-yl)-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.02,7]nonadeca-1(19),2(7),3,5,15,17-hexaen-5-yl]carbamate