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    首页 分子通 按分子结构分类 有机化合物 苯丙烷和聚酮 大环内酰胺类

    大环内酰胺类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— (4S,7S,14S,17S)-1,5,11,15-tetraaza-4,14-bis-(2'-propyl)tricyclo[15.3.0.0<sup>7,11</sup>]eicosan-6,16-dione —— C22H40N4O2
    (4S,7S,14S,17S)-1,5,11,15-tetraaza-4,14-bis-(2'-propyl)tricyclo[15.3.0.0<sup>7,11</sup>]eicosan-6,16-dione
    —— 3-(20-ethyl-7-isopropylsulfanyl-4-methyl-3,12-dioxo-13-oxa-4,11-diaza-tricyclo[14.2.2.1<sup>6,10</sup>]henicosa-1(19),6,8,10(21),16(20),17-hexaen-2-ylamino)-benzamide —— C31H36N4O4S
    3-(20-ethyl-7-isopropylsulfanyl-4-methyl-3,12-dioxo-13-oxa-4,11-diaza-tricyclo[14.2.2.1<sup>6,10</sup>]henicosa-1(19),6,8,10(21),16(20),17-hexaen-2-ylamino)-benzamide
    —— naphthomycin G —— C45H54N2O12S
    naphthomycin G
    —— 10-benzyl-15,16,17-trihydroxy-3,8,18-trioxa-11-azabicyclo[12.3.1]octadecan-12-one —— C21H31NO7
    10-benzyl-15,16,17-trihydroxy-3,8,18-trioxa-11-azabicyclo[12.3.1]octadecan-12-one
    —— 10-benzyl-15,16,17-trihydroxy-3,8,18-trioxa-11-azabicyclo[12.3.1]octadecan-12-one —— C21H31NO7
    10-benzyl-15,16,17-trihydroxy-3,8,18-trioxa-11-azabicyclo[12.3.1]octadecan-12-one
    —— methyl N-[(10R,14S)-14-[5-amino-1-(3-chlorophenyl)-1H-pyrazole-4-amido]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.0<sup>2,7</sup>]nonadeca-1(19),2(7),3,5,15,17-hexaen-5-yl]carbamate bis-trifluoroacetic acid salt —— 2C2HF3O2*C30H30ClN7O4
    methyl N-[(10R,14S)-14-[5-amino-1-(3-chlorophenyl)-1H-pyrazole-4-amido]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.0<sup>2,7</sup>]nonadeca-1(19),2(7),3,5,15,17-hexaen-5-yl]carbamate bis-trifluoroacetic acid salt
    —— (10R,14S)-14-[4-(3-chloro-2,6-difluorophenyl)-6-oxo-1,2,3,6-tetrahydropyridin-1-yl]-4,10-dimethyl-8,16-diazatricyclo[13.3.1.0<sup>2</sup>'<sup>7</sup>]nonadeca-1(19),2(7),3,5,15,17-hexaen-9-one —— C30H28ClF2N3O2
    (10R,14S)-14-[4-(3-chloro-2,6-difluorophenyl)-6-oxo-1,2,3,6-tetrahydropyridin-1-yl]-4,10-dimethyl-8,16-diazatricyclo[13.3.1.0<sup>2</sup>'<sup>7</sup>]nonadeca-1(19),2(7),3,5,15,17-hexaen-9-one
    —— 4,5,6,7,9,13a,14,15,16,17,18,18a-dodecahydro-19-methyl-10,13-etheno-15,18-imino-1H-cyclohept[m][1,8]oxaazacyclopentadecine-3,8-dione —— C21H28N2O3
    4,5,6,7,9,13a,14,15,16,17,18,18a-dodecahydro-19-methyl-10,13-etheno-15,18-imino-1H-cyclohept[m][1,8]oxaazacyclopentadecine-3,8-dione
    —— (1S,4R,6S,17S)-13-methyl-17-(4-nitro-benzoyloxy)-2,14-dioxo-3,13,15-triaza-tricyclo[13.3.0.0(4,6)]-octadec-7-ene-4-carboxylic acid ethyl ester —— C26H32N4O8
    (1S,4R,6S,17S)-13-methyl-17-(4-nitro-benzoyloxy)-2,14-dioxo-3,13,15-triaza-tricyclo[13.3.0.0(4,6)]-octadec-7-ene-4-carboxylic acid ethyl ester
    —— (E)-10-(ethyl(7-methyl-7-azaspiro[3.5]nonan-2-yl)amino)-3-methyl-5,6,15,16-tetrahydrobenzo[c]pyrido[4,3-j][1]azacyclododecine-1,14(2H,9H)-dione —— C30H40N4O2
    (E)-10-(ethyl(7-methyl-7-azaspiro[3.5]nonan-2-yl)amino)-3-methyl-5,6,15,16-tetrahydrobenzo[c]pyrido[4,3-j][1]azacyclododecine-1,14(2H,9H)-dione
    —— N-tosyl-4,5-benzoazacyclododeca-6-yn-8-en-2-one —— C22H21NO3S
    N-tosyl-4,5-benzoazacyclododeca-6-yn-8-en-2-one
    —— 6,7,8,9,10,11-hexahydro-18H-5,21:12,17-dimethenodibenzo[i,o]pyrrolo[3,4-l][1,8]diazacyclohexadecine-18,20-dione —— C26H23N3O2
    6,7,8,9,10,11-hexahydro-18H-5,21:12,17-dimethenodibenzo[i,o]pyrrolo[3,4-l][1,8]diazacyclohexadecine-18,20-dione
    —— 17-[2-(carboxy)ethyl]amino-17-demethoxygeldanamycin —— C31H43N3O10
    17-[2-(carboxy)ethyl]amino-17-demethoxygeldanamycin
    —— 17-(2-furoyl)amino-17-demethoxygeldanamycin —— C33H41N3O10
    17-(2-furoyl)amino-17-demethoxygeldanamycin
    —— (1R,4R,6S,15R,17R)-17-[2-(3-fluoro-phenyl)-7-methoxy-8-methyl-quinazolin-4-yloxy]-13-methyl-2,14-dioxo-3,13-diaza-tricyclo[13.3.0.0(4,6)]octadec-7-ene-4-carboxylic acid ethyl ester —— C36H41FN4O6
    (1R,4R,6S,15R,17R)-17-[2-(3-fluoro-phenyl)-7-methoxy-8-methyl-quinazolin-4-yloxy]-13-methyl-2,14-dioxo-3,13-diaza-tricyclo[13.3.0.0(4,6)]octadec-7-ene-4-carboxylic acid ethyl ester
    —— 19-aminogeldanamycin —— C29H41N3O9
    19-aminogeldanamycin
    —— methyl N-[(10R,14S)-14-[4-(3-chloro-6-cyano-2-fluorophenyl)-6-oxo-1,2,3,6-tetrahydropyridin-1-yl]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.0<sup>2</sup>'<sup>7</sup>]nonadeca-1(19),2,4,6,15,17-hexaen-5-yl]carbamate trifluoroacetic acid —— (x)C2HF3O2*C32H29ClFN5O4
    methyl N-[(10R,14S)-14-[4-(3-chloro-6-cyano-2-fluorophenyl)-6-oxo-1,2,3,6-tetrahydropyridin-1-yl]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.0<sup>2</sup>'<sup>7</sup>]nonadeca-1(19),2,4,6,15,17-hexaen-5-yl]carbamate trifluoroacetic acid
    —— 10-aza-[11]-(2,3)-thiophenophane-1,9-dione —— C14H19NO2S
    10-aza-[11]-(2,3)-thiophenophane-1,9-dione
    —— 2,3-dioxo-8,11-dithia-1,4-diazacyclotetradecane —— C10H18N2O2S2
    2,3-dioxo-8,11-dithia-1,4-diazacyclotetradecane
    —— 17-azetidinyl-11-<<(4'-methyl-1'-piperazino)sulfamyl>carbonyl>geldanamycin —— C37H54N6O11S
    17-azetidinyl-11-<<(4'-methyl-1'-piperazino)sulfamyl>carbonyl>geldanamycin
    —— (1R,4R,6S,15R,17R)-17-[7-methoxy-2-(4-methoxy-phenyl)-8-methyl-quinazolin-4-yloxy]-13-methyl-2,14-dioxo-3,13-diaza-tricyclo[13.3.0.0(4,6)]octadec-7-ene-4-carboxylic acid ethyl ester —— C37H44N4O7
    (1R,4R,6S,15R,17R)-17-[7-methoxy-2-(4-methoxy-phenyl)-8-methyl-quinazolin-4-yloxy]-13-methyl-2,14-dioxo-3,13-diaza-tricyclo[13.3.0.0(4,6)]octadec-7-ene-4-carboxylic acid ethyl ester
    —— 6,9-diphenyl-6,7,8,9-tetrahydrodibenzo[c,k][1,2,6,9]dithiadiazacyclododecine-5,10-dione —— C28H22N2O2S2
    6,9-diphenyl-6,7,8,9-tetrahydrodibenzo[c,k][1,2,6,9]dithiadiazacyclododecine-5,10-dione
    —— 17-allylamino-17-demethoxygeldanamycin —— C31H43N3O8
    17-allylamino-17-demethoxygeldanamycin
    —— (2S,12S)-1,4,10,13-tetraaza-2,12-dimethyl-7,16,19-trioxa-3,11,14,21-cycloheneicosatetraone —— C16H28N4O7
    (2S,12S)-1,4,10,13-tetraaza-2,12-dimethyl-7,16,19-trioxa-3,11,14,21-cycloheneicosatetraone
    —— 11-O-methyl-17-(2-(4-imidazolyl)ethyl)amino-17-demethoxy-geldanamycin —— C34H47N5O8
    11-O-methyl-17-(2-(4-imidazolyl)ethyl)amino-17-demethoxy-geldanamycin
    —— 17-(4-methoxybenzoyl)amino-17-demethoxygeldanamycin —— C36H45N3O10
    17-(4-methoxybenzoyl)amino-17-demethoxygeldanamycin
    —— naphthomycin A —— C40H46ClNO9
    naphthomycin A
    —— 4,6-(1,17-(2,16-diaza-3,15-dioxo-9-oxothiaheptadecamethylene))-3,7-dimethyl-1,5-diazabicyclo<3.3.0>octa-3,6-diene-2,8-dione —— C22H32N4O5S
    4,6-(1,17-(2,16-diaza-3,15-dioxo-9-oxothiaheptadecamethylene))-3,7-dimethyl-1,5-diazabicyclo<3.3.0>octa-3,6-diene-2,8-dione
    —— (S)-8-amino-N-(4-fluorobenzyl)-7-oxo-2,6,13-triaza-1(2,4)-pyrimidinacyclotridecaphane-1-carboxamide —— C21H28FN7O2
    (S)-8-amino-N-(4-fluorobenzyl)-7-oxo-2,6,13-triaza-1(2,4)-pyrimidinacyclotridecaphane-1-carboxamide
    —— tert-butyl N-[(10R,14S)-5-[(methoxycarbonyl)amino]-10-methyl-9,11-dioxo-8,16-diazatricyclo[13.3.1.0<sup>2</sup>'<sup>7</sup>]nonadeca-1(18),2,4,6,15(19),16-hexaen-14-15 yl]carbamate —— C25H30N4O6
    tert-butyl N-[(10R,14S)-5-[(methoxycarbonyl)amino]-10-methyl-9,11-dioxo-8,16-diazatricyclo[13.3.1.0<sup>2</sup>'<sup>7</sup>]nonadeca-1(18),2,4,6,15(19),16-hexaen-14-15 yl]carbamate
    —— methyl N-[(10R,14S)-14-[1-(3-chloro-2-fluorophenyl)-5-methyl-1H-1,2,3-triazole-4-amido]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.0<sup>2,7</sup>]nonadeca-1(19),2(7),3,5,15,17-hexaen-5-yl]carbamate —— C30H29ClFN7O4
    methyl N-[(10R,14S)-14-[1-(3-chloro-2-fluorophenyl)-5-methyl-1H-1,2,3-triazole-4-amido]-10-methyl-9-oxo-8,16-diazatricyclo[13.3.1.0<sup>2,7</sup>]nonadeca-1(19),2(7),3,5,15,17-hexaen-5-yl]carbamate
    —— rifabutin —— C46H62N4O11
    rifabutin
    —— (E)-10-(ethyl(1-ethylpiperidin-4-yl)amino)-3-methyl-5,6,15,16-tetrahydrobenzo[c]pyrido[4,3-j][1]azacyclododecine-1,14(2H,9H)-dione —— C28H38N4O2
    (E)-10-(ethyl(1-ethylpiperidin-4-yl)amino)-3-methyl-5,6,15,16-tetrahydrobenzo[c]pyrido[4,3-j][1]azacyclododecine-1,14(2H,9H)-dione
    —— (+)-(4S)-4-[(octylthio)methyl]-1,5,9-triazacyclotridecan-2-one —— C19H39N3OS
    (+)-(4S)-4-[(octylthio)methyl]-1,5,9-triazacyclotridecan-2-one
    —— (S)-N-((S)-4-methyl-1-oxopentan-2-yl)-4,6-dioxo-5<sup>1</sup>H-11,16-dioxa-7-aza-5(2,5)-pyrrola-1,10(1,4)-dibenzenacyclohexadecaphane-8-carboxamide —— C33H39N3O6
    (S)-N-((S)-4-methyl-1-oxopentan-2-yl)-4,6-dioxo-5<sup>1</sup>H-11,16-dioxa-7-aza-5(2,5)-pyrrola-1,10(1,4)-dibenzenacyclohexadecaphane-8-carboxamide
    —— (Z)-1,9-Dioxa-4-aza-cycloheptadec-6-en-3-one —— C14H25NO3
    (Z)-1,9-Dioxa-4-aza-cycloheptadec-6-en-3-one
    —— (E)-1,9-Dioxa-4-aza-cycloheptadec-6-en-3-one —— C14H25NO3
    (E)-1,9-Dioxa-4-aza-cycloheptadec-6-en-3-one
    —— 16-[1-(2,2-difluorocyclopropanecarbonyl)piperidin-4-yl]-4,5,12,15,16,19,25-heptaazatetracyclo[19.3.1.1<sup>2</sup>,<sup>5</sup>.0<sup>1</sup><sup>4</sup>,<sup>18</sup>]hexacosa-1(24),2(26),3,14,17,21(25),22-heptaene-13,20-dione —— C28H32F2N8O3
    16-[1-(2,2-difluorocyclopropanecarbonyl)piperidin-4-yl]-4,5,12,15,16,19,25-heptaazatetracyclo[19.3.1.1<sup>2</sup>,<sup>5</sup>.0<sup>1</sup><sup>4</sup>,<sup>18</sup>]hexacosa-1(24),2(26),3,14,17,21(25),22-heptaene-13,20-dione
    —— 17-(allylamino)-11-<(azetidinylsulfamyl)carbonyl>geldanamycin —— C35H49N5O11S
    17-(allylamino)-11-<(azetidinylsulfamyl)carbonyl>geldanamycin
    —— E/Z-2-azacyclooctadec-9-enone —— C17H31NO
    E/Z-2-azacyclooctadec-9-enone
    —— (Z)-Azacyclooctadec-11-en-2-one —— C17H31NO
    (Z)-Azacyclooctadec-11-en-2-one
    —— (E)-Azacyclooctadec-11-en-2-one —— C17H31NO
    (E)-Azacyclooctadec-11-en-2-one
    —— maytansin-3N-methyl-L-alaninepropanamide-3-thiol 139504-50-0 C35H48ClN3O10S
    maytansin-3N-methyl-L-alaninepropanamide-3-thiol
    —— DM-1 139504-50-0 C35H48ClN3O10S
    DM-1
    —— N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine —— C35H48ClN3O10S
    N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine
    —— D-N<sup>2'</sup>-deacetyl-N<sup>2'</sup>-(3-mercapto-1-oxopropyl)maytansine —— C35H48ClN3O10S
    D-N<sup>2'</sup>-deacetyl-N<sup>2'</sup>-(3-mercapto-1-oxopropyl)maytansine
    —— methyl (R)-1,3,4,5,6,7,8,10-octahydro-14-hydroxy-12-methoxy-11-methyl-6,10-dioxo-9,2,5-benzoxathiaazacyclododecine-4-carboxylate —— C17H21NO7S
    methyl (R)-1,3,4,5,6,7,8,10-octahydro-14-hydroxy-12-methoxy-11-methyl-6,10-dioxo-9,2,5-benzoxathiaazacyclododecine-4-carboxylate
    —— 17-(4-(3,5,6-trimethylpyrazine-2-carboxamido)butylamino)-17-demethoxygeldanamycin —— C40H56N6O9
    17-(4-(3,5,6-trimethylpyrazine-2-carboxamido)butylamino)-17-demethoxygeldanamycin
    —— (1<sup>4</sup>S,1<sup>6</sup>S,3<sup>2</sup>R,3<sup>3</sup>R,2R,4S,10E,12E,14R)-8<sup>6</sup>-chloro-1<sup>4</sup>-hydroxy-8<sup>5</sup>,14-dimethoxy-3<sup>3</sup>,2,7,10-tetramethyl-1<sup>2</sup>,6-dioxo-7-aza-1(6,4)-oxazinana-3(2,3)-oxirana-8(1,3)-benzenacyclotetradecaphane-10,12-dien-4-yl methyl-L-alaninate —— C32H44ClN3O9
    (1<sup>4</sup>S,1<sup>6</sup>S,3<sup>2</sup>R,3<sup>3</sup>R,2R,4S,10E,12E,14R)-8<sup>6</sup>-chloro-1<sup>4</sup>-hydroxy-8<sup>5</sup>,14-dimethoxy-3<sup>3</sup>,2,7,10-tetramethyl-1<sup>2</sup>,6-dioxo-7-aza-1(6,4)-oxazinana-3(2,3)-oxirana-8(1,3)-benzenacyclotetradecaphane-10,12-dien-4-yl methyl-L-alaninate
    —— maytansinol 3-(S)-α-N-methylaminopropionate —— C32H44ClN3O9
    maytansinol 3-(S)-α-N-methylaminopropionate