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    首页 分子通 按分子结构分类 有机化合物 苯丙烷和聚酮 大环内酰胺类

    大环内酰胺类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 18-isoquinolin-1-yloxy-N-(1-methylcyclopropyl)sulfonyl-2,15-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide —— C31H38N4O6S
    18-isoquinolin-1-yloxy-N-(1-methylcyclopropyl)sulfonyl-2,15-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide
    —— Ethane;1-(6-methyl-4-propan-2-yl-6,11-diazatetracyclo[7.6.1.03,7.012,16]hexadeca-1(16),12,14-trien-11-yl)ethanone —— C22H34N2O
    Ethane;1-(6-methyl-4-propan-2-yl-6,11-diazatetracyclo[7.6.1.03,7.012,16]hexadeca-1(16),12,14-trien-11-yl)ethanone
    —— Ethane;17-pyridin-1-ium-1-yl-3,10-diazahexacyclo[13.6.2.02,10.04,9.012,22.019,23]tricosa-1(22),2,4,6,8,12,14,19(23),20-nonaene-11,16,18-trione —— C28H20N3O3+
    Ethane;17-pyridin-1-ium-1-yl-3,10-diazahexacyclo[13.6.2.02,10.04,9.012,22.019,23]tricosa-1(22),2,4,6,8,12,14,19(23),20-nonaene-11,16,18-trione
    —— 2-(5,13-dioxo-1-oxa-4-azacyclotridec-8-en-6-yl)-N-[1-(hydroxymethyl)cyclopentyl]acetamide —— C19H30N2O5
    2-(5,13-dioxo-1-oxa-4-azacyclotridec-8-en-6-yl)-N-[1-(hydroxymethyl)cyclopentyl]acetamide
    —— 18-[tert-butyl(dimethyl)silyl]oxy-N-cyclopropylsulfonyl-2,15-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide —— C27H45N3O6SSi
    18-[tert-butyl(dimethyl)silyl]oxy-N-cyclopropylsulfonyl-2,15-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide
    —— methyl N-[(14S)-14-[[(E)-3-[5-chloro-2-(tetrazol-1-yl)phenyl]prop-2-enoyl]amino]-11,12-dihydroxy-9-oxo-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2(7),3,5,15-pentaen-5-yl]carbamate —— C27H26ClN9O6
    methyl N-[(14S)-14-[[(E)-3-[5-chloro-2-(tetrazol-1-yl)phenyl]prop-2-enoyl]amino]-11,12-dihydroxy-9-oxo-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2(7),3,5,15-pentaen-5-yl]carbamate
    —— methyl N-[(14S)-9-oxo-14-(1,2,3,4-tetrahydroquinoline-6-carbonylamino)-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2(7),3,5,15-pentaen-5-yl]carbamate —— C27H30N6O4
    methyl N-[(14S)-9-oxo-14-(1,2,3,4-tetrahydroquinoline-6-carbonylamino)-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2(7),3,5,15-pentaen-5-yl]carbamate
    —— methyl N-[(14S)-14-[[(E)-3-[5-chloro-2-(triazol-1-yl)phenyl]prop-2-enoyl]amino]-9-oxo-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2(7),3,5,15-pentaen-5-yl]carbamate —— C28H27ClN8O4
    methyl N-[(14S)-14-[[(E)-3-[5-chloro-2-(triazol-1-yl)phenyl]prop-2-enoyl]amino]-9-oxo-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2(7),3,5,15-pentaen-5-yl]carbamate
    —— methyl N-[(14S)-17-chloro-14-[(4,6-difluoro-1-methylindole-5-carbonyl)amino]-10-methyl-9-oxo-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2(7),3,5,15(18)-pentaen-5-yl]carbamate —— C28H27ClF2N6O4
    methyl N-[(14S)-17-chloro-14-[(4,6-difluoro-1-methylindole-5-carbonyl)amino]-10-methyl-9-oxo-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2(7),3,5,15(18)-pentaen-5-yl]carbamate
    —— methyl N-[(14S)-9-oxo-14-(quinoline-6-carbonylamino)-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2(7),3,5,15-pentaen-5-yl]carbamate —— C27H26N6O4
    methyl N-[(14S)-9-oxo-14-(quinoline-6-carbonylamino)-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2(7),3,5,15-pentaen-5-yl]carbamate
    —— methyl N-[(11E,14S)-9-oxo-14-(1,2,3,4-tetrahydroisoquinoline-6-carbonylamino)-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2(7),3,5,11,15-hexaen-5-yl]carbamate —— C27H28N6O4
    methyl N-[(11E,14S)-9-oxo-14-(1,2,3,4-tetrahydroisoquinoline-6-carbonylamino)-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2(7),3,5,11,15-hexaen-5-yl]carbamate
    —— US11136327, Example I-106 —— C27H24ClN9O4
    US11136327, Example I-106
    —— methyl N-[(14S)-9-oxo-14-(quinoline-7-carbonylamino)-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2(7),3,5,15-pentaen-5-yl]carbamate —— C27H26N6O4
    methyl N-[(14S)-9-oxo-14-(quinoline-7-carbonylamino)-8,16,18-triazatricyclo[13.2.1.02,7]octadeca-1(17),2(7),3,5,15-pentaen-5-yl]carbamate
    —— (2S)-2-[(2R,6R,9E,13E,15Z)-2,9-dimethyl-4,12-dioxo-6-sulfanyl-19-thia-3,20-diazabicyclo[15.2.1]icosa-1(20),9,13,15,17-pentaen-6-yl]propanoic acid —— C22H28N2O4S2
    (2S)-2-[(2R,6R,9E,13E,15Z)-2,9-dimethyl-4,12-dioxo-6-sulfanyl-19-thia-3,20-diazabicyclo[15.2.1]icosa-1(20),9,13,15,17-pentaen-6-yl]propanoic acid
    —— 11-Benzyl-6-[2-[2-(hydroxymethyl)pyrrolidin-1-yl]-2-oxoethyl]-3-[(4-phenylmethoxyphenyl)methyl]-1-oxa-4-azacyclododec-8-ene-5,12-dione —— C38H44N2O6
    11-Benzyl-6-[2-[2-(hydroxymethyl)pyrrolidin-1-yl]-2-oxoethyl]-3-[(4-phenylmethoxyphenyl)methyl]-1-oxa-4-azacyclododec-8-ene-5,12-dione
    —— Benzyl 12-benzyl-6-[2-[benzyl(2-hydroxyethyl)amino]-2-oxoethyl]-5,13-dioxo-1-oxa-4-azacyclotridec-8-ene-3-carboxylate —— C37H42N2O7
    Benzyl 12-benzyl-6-[2-[benzyl(2-hydroxyethyl)amino]-2-oxoethyl]-5,13-dioxo-1-oxa-4-azacyclotridec-8-ene-3-carboxylate
    —— 2-(3-tert-butyl-5,12-dioxo-1-oxa-4-azacyclododec-8-en-6-yl)-N-[2-(2-hydroxyethoxy)ethyl]acetamide —— C20H34N2O6
    2-(3-tert-butyl-5,12-dioxo-1-oxa-4-azacyclododec-8-en-6-yl)-N-[2-(2-hydroxyethoxy)ethyl]acetamide
    —— 11-benzyl-3-tert-butyl-6-[2-[3-(hydroxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-1-oxa-4-azacyclododec-8-ene-5,12-dione —— C33H42N2O5
    11-benzyl-3-tert-butyl-6-[2-[3-(hydroxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-1-oxa-4-azacyclododec-8-ene-5,12-dione
    —— 3-benzyl-6-[2-[3-(hydroxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-1-oxa-4-azacyclododec-8-ene-5,12-dione —— C29H34N2O5
    3-benzyl-6-[2-[3-(hydroxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-1-oxa-4-azacyclododec-8-ene-5,12-dione
    —— 3-tert-butyl-6-[2-[3-(hydroxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-1-oxa-4-azacyclododec-8-ene-5,12-dione —— C26H36N2O5
    3-tert-butyl-6-[2-[3-(hydroxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-1-oxa-4-azacyclododec-8-ene-5,12-dione
    —— benzyl N-[3-tert-butyl-6-[2-[3-(hydroxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-5,12-dioxo-1-oxa-4-azacyclododec-8-en-11-yl]carbamate —— C34H43N3O7
    benzyl N-[3-tert-butyl-6-[2-[3-(hydroxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-5,12-dioxo-1-oxa-4-azacyclododec-8-en-11-yl]carbamate
    —— 11-benzyl-3-(cyclohexylmethyl)-6-[2-[3-(hydroxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-1-oxa-4-azacyclododec-8-ene-5,12-dione —— C36H46N2O5
    11-benzyl-3-(cyclohexylmethyl)-6-[2-[3-(hydroxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-1-oxa-4-azacyclododec-8-ene-5,12-dione
    —— benzyl N-[3-(cyclohexylmethyl)-6-[2-[3-(hydroxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-5,12-dioxo-1-oxa-4-azacyclododec-8-en-11-yl]carbamate —— C37H47N3O7
    benzyl N-[3-(cyclohexylmethyl)-6-[2-[3-(hydroxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-5,12-dioxo-1-oxa-4-azacyclododec-8-en-11-yl]carbamate
    —— 2-[12-benzyl-5,13-dioxo-3-(phenylmethoxymethyl)-1-oxa-4-azacyclotridec-8-en-6-yl]-N-[2-(2-hydroxyethoxy)ethyl]acetamide —— C32H42N2O7
    2-[12-benzyl-5,13-dioxo-3-(phenylmethoxymethyl)-1-oxa-4-azacyclotridec-8-en-6-yl]-N-[2-(2-hydroxyethoxy)ethyl]acetamide
    —— 2-(12-benzyl-5,13-dioxo-3-propan-2-yl-1-oxa-4-azacyclotridec-8-en-6-yl)-N-[1-hydroxy-3-(4-phenylmethoxyphenyl)propan-2-yl]acetamide —— C39H48N2O6
    2-(12-benzyl-5,13-dioxo-3-propan-2-yl-1-oxa-4-azacyclotridec-8-en-6-yl)-N-[1-hydroxy-3-(4-phenylmethoxyphenyl)propan-2-yl]acetamide
    —— benzyl N-[4-[6-[2-[[1-(hydroxymethyl)cyclopentyl]amino]-2-oxoethyl]-5,12-dioxo-1-oxa-4-azacyclododec-8-en-3-yl]butyl]carbamate —— C30H43N3O7
    benzyl N-[4-[6-[2-[[1-(hydroxymethyl)cyclopentyl]amino]-2-oxoethyl]-5,12-dioxo-1-oxa-4-azacyclododec-8-en-3-yl]butyl]carbamate
    —— 6-[2-[2-(Hydroxymethyl)pyrrolidin-1-yl]-2-oxoethyl]-3-[(4-phenylmethoxyphenyl)methyl]-1-oxa-4-azacyclotridec-8-ene-5,13-dione —— C32H40N2O6
    6-[2-[2-(Hydroxymethyl)pyrrolidin-1-yl]-2-oxoethyl]-3-[(4-phenylmethoxyphenyl)methyl]-1-oxa-4-azacyclotridec-8-ene-5,13-dione
    —— 2-(5,14-dioxo-2-phenyl-1-oxa-4-azacyclotetradec-8-en-6-yl)-N-(1-hydroxypropan-2-yl)acetamide —— C23H32N2O5
    2-(5,14-dioxo-2-phenyl-1-oxa-4-azacyclotetradec-8-en-6-yl)-N-(1-hydroxypropan-2-yl)acetamide
    —— 2,2-Dimethyl-17,18-dioxa-8,12-diazatricyclo[12.2.1.1~3,6~]octadeca-1(16),3,5,14-tetraene-7,13-dione —— C16H18N2O4
    2,2-Dimethyl-17,18-dioxa-8,12-diazatricyclo[12.2.1.1~3,6~]octadeca-1(16),3,5,14-tetraene-7,13-dione
    —— N-(1-hydroxypropan-2-yl)-2-[3-(methoxymethyl)-5,13-dioxo-2-phenyl-1-oxa-4-azacyclotridec-8-en-6-yl]acetamide —— C24H34N2O6
    N-(1-hydroxypropan-2-yl)-2-[3-(methoxymethyl)-5,13-dioxo-2-phenyl-1-oxa-4-azacyclotridec-8-en-6-yl]acetamide
    —— benzyl N-[6-[2-[[1-(hydroxymethyl)cyclopentyl]amino]-2-oxoethyl]-5,12-dioxo-1-oxa-4-azacyclododec-8-en-11-yl]carbamate —— C26H35N3O7
    benzyl N-[6-[2-[[1-(hydroxymethyl)cyclopentyl]amino]-2-oxoethyl]-5,12-dioxo-1-oxa-4-azacyclododec-8-en-11-yl]carbamate
    —— N-(1-hydroxypropan-2-yl)-2-(3-methyl-5,12-dioxo-1-oxa-4-azacyclododec-8-en-6-yl)acetamide —— C16H26N2O5
    N-(1-hydroxypropan-2-yl)-2-(3-methyl-5,12-dioxo-1-oxa-4-azacyclododec-8-en-6-yl)acetamide
    —— 2-[12-benzyl-3-(1H-indol-3-ylmethyl)-5,13-dioxo-1-oxa-4-azacyclotridec-8-en-6-yl]-N-[1-(hydroxymethyl)cyclopentyl]acetamide —— C35H43N3O5
    2-[12-benzyl-3-(1H-indol-3-ylmethyl)-5,13-dioxo-1-oxa-4-azacyclotridec-8-en-6-yl]-N-[1-(hydroxymethyl)cyclopentyl]acetamide
    —— Benzyl 6-[2-[[1-hydroxy-3-(4-phenylmethoxyphenyl)propan-2-yl]amino]-2-oxoethyl]-5,13-dioxo-1-oxa-4-azacyclotridec-8-ene-3-carboxylate —— C37H42N2O8
    Benzyl 6-[2-[[1-hydroxy-3-(4-phenylmethoxyphenyl)propan-2-yl]amino]-2-oxoethyl]-5,13-dioxo-1-oxa-4-azacyclotridec-8-ene-3-carboxylate
    —— benzyl N-[3-(cyclohexylmethyl)-6-[2-[2-(hydroxymethyl)pyrrolidin-1-yl]-2-oxoethyl]-5,12-dioxo-1-oxa-4-azacyclododec-8-en-11-yl]carbamate —— C32H45N3O7
    benzyl N-[3-(cyclohexylmethyl)-6-[2-[2-(hydroxymethyl)pyrrolidin-1-yl]-2-oxoethyl]-5,12-dioxo-1-oxa-4-azacyclododec-8-en-11-yl]carbamate
    —— 3-(benzylsulfanylmethyl)-6-[2-[3-(hydroxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-1-oxa-4-azacyclotridec-8-ene-5,13-dione —— C31H38N2O5S
    3-(benzylsulfanylmethyl)-6-[2-[3-(hydroxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-1-oxa-4-azacyclotridec-8-ene-5,13-dione
    —— benzyl N-[6-[2-[2-(2-hydroxyethoxy)ethylamino]-2-oxoethyl]-3-(1H-indol-3-ylmethyl)-5,12-dioxo-1-oxa-4-azacyclododec-8-en-11-yl]carbamate —— C33H40N4O8
    benzyl N-[6-[2-[2-(2-hydroxyethoxy)ethylamino]-2-oxoethyl]-3-(1H-indol-3-ylmethyl)-5,12-dioxo-1-oxa-4-azacyclododec-8-en-11-yl]carbamate
    —— 2-(13-benzyl-5,14-dioxo-3-propan-2-yl-1-oxa-4-azacyclotetradec-8-en-6-yl)-N-(1-hydroxy-3-phenylpropan-2-yl)acetamide —— C33H44N2O5
    2-(13-benzyl-5,14-dioxo-3-propan-2-yl-1-oxa-4-azacyclotetradec-8-en-6-yl)-N-(1-hydroxy-3-phenylpropan-2-yl)acetamide
    —— 2,13,15,17-Tetrahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-26-piperidin-1-yl-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(28),2,4,9,19,21,25-heptaene-6,23,27,29-tetrone —— C40H52N2O11
    2,13,15,17-Tetrahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-26-piperidin-1-yl-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(28),2,4,9,19,21,25-heptaene-6,23,27,29-tetrone
    —— benzyl N-[3-[2-(1-hydroxypropan-2-ylamino)-2-oxoethyl]-2,9-dioxo-10-oxa-1-azabicyclo[10.3.0]pentadec-5-en-8-yl]carbamate —— C26H35N3O7
    benzyl N-[3-[2-(1-hydroxypropan-2-ylamino)-2-oxoethyl]-2,9-dioxo-10-oxa-1-azabicyclo[10.3.0]pentadec-5-en-8-yl]carbamate
    —— 13-benzyl-6-[2-[3-(hydroxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-2-methyl-1-oxa-4-azacyclotetradec-8-ene-5,14-dione —— C32H40N2O5
    13-benzyl-6-[2-[3-(hydroxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-2-methyl-1-oxa-4-azacyclotetradec-8-ene-5,14-dione
    —— 2-[12-benzyl-3-(benzylsulfanylmethyl)-5,13-dioxo-1-oxa-4-azacyclotridec-8-en-6-yl]-N-[2-(2-hydroxyethoxy)ethyl]acetamide —— C32H42N2O6S
    2-[12-benzyl-3-(benzylsulfanylmethyl)-5,13-dioxo-1-oxa-4-azacyclotridec-8-en-6-yl]-N-[2-(2-hydroxyethoxy)ethyl]acetamide
    —— 6-[2-[2-(Hydroxymethyl)pyrrolidin-1-yl]-2-oxoethyl]-3-phenyl-1-oxa-4-azacyclotetradec-8-ene-5,14-dione —— C25H34N2O5
    6-[2-[2-(Hydroxymethyl)pyrrolidin-1-yl]-2-oxoethyl]-3-phenyl-1-oxa-4-azacyclotetradec-8-ene-5,14-dione
    —— 11-benzyl-6-[2-[3-(hydroxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-3-(methoxymethyl)-2-phenyl-1-oxa-4-azacyclododec-8-ene-5,12-dione —— C37H42N2O6
    11-benzyl-6-[2-[3-(hydroxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-3-(methoxymethyl)-2-phenyl-1-oxa-4-azacyclododec-8-ene-5,12-dione
    —— 2-[13-benzyl-3-(1H-indol-3-ylmethyl)-5,14-dioxo-1-oxa-4-azacyclotetradec-8-en-6-yl]-N-(1-hydroxypropan-2-yl)acetamide —— C33H41N3O5
    2-[13-benzyl-3-(1H-indol-3-ylmethyl)-5,14-dioxo-1-oxa-4-azacyclotetradec-8-en-6-yl]-N-(1-hydroxypropan-2-yl)acetamide
    —— 2-(11-benzyl-3,3-dimethyl-5,12-dioxo-1-oxa-4-azacyclododec-8-en-6-yl)-N-(1-hydroxy-3-phenylpropan-2-yl)acetamide —— C30H38N2O5
    2-(11-benzyl-3,3-dimethyl-5,12-dioxo-1-oxa-4-azacyclododec-8-en-6-yl)-N-(1-hydroxy-3-phenylpropan-2-yl)acetamide
    —— 11-benzyl-6-[2-[3-(hydroxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-1-oxa-4-azacyclododec-8-ene-5,12-dione —— C29H34N2O5
    11-benzyl-6-[2-[3-(hydroxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-1-oxa-4-azacyclododec-8-ene-5,12-dione
    —— 6-Oxa-15,20,24,27-tetraazatetracyclo[13.9.6.2(2,5).1(7,11)]tritriaconta-2,4,7,9,11(31),12,32-heptaene-14,26-dione, 8-hydroxy-, [s-(Z)]- —— C28H36N4O4
    6-Oxa-15,20,24,27-tetraazatetracyclo[13.9.6.2(2,5).1(7,11)]tritriaconta-2,4,7,9,11(31),12,32-heptaene-14,26-dione, 8-hydroxy-, [s-(Z)]-
    —— benzyl N-[4-[11-benzyl-6-[2-[2-(hydroxymethyl)pyrrolidin-1-yl]-2-oxoethyl]-5,12-dioxo-1-oxa-4-azacyclododec-8-en-3-yl]butyl]carbamate —— C36H47N3O7
    benzyl N-[4-[11-benzyl-6-[2-[2-(hydroxymethyl)pyrrolidin-1-yl]-2-oxoethyl]-5,12-dioxo-1-oxa-4-azacyclododec-8-en-3-yl]butyl]carbamate
    —— benzyl N-[3-(benzylsulfanylmethyl)-6-[2-[2-(hydroxymethyl)pyrrolidin-1-yl]-2-oxoethyl]-5,12-dioxo-1-oxa-4-azacyclododec-8-en-11-yl]carbamate —— C33H41N3O7S
    benzyl N-[3-(benzylsulfanylmethyl)-6-[2-[2-(hydroxymethyl)pyrrolidin-1-yl]-2-oxoethyl]-5,12-dioxo-1-oxa-4-azacyclododec-8-en-11-yl]carbamate