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    首页 分子通 按分子结构分类 有机化合物 苯丙烷和聚酮 大环内酰胺类

    大环内酰胺类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— [(1S,4R,6S,7Z,11S,13R,18R)-11,13-dimethyl-4-[(1-methylcyclopropyl)sulfonylcarbamoyl]-2,15-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-en-18-yl] N-[2-(trifluoromethyl)phenyl]carbamate —— C32H41F3N4O7S
    [(1S,4R,6S,7Z,11S,13R,18R)-11,13-dimethyl-4-[(1-methylcyclopropyl)sulfonylcarbamoyl]-2,15-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-en-18-yl] N-[2-(trifluoromethyl)phenyl]carbamate
    —— [(1S,4R,6S,7Z,11S,13R,18R)-11,13-dimethyl-4-[(1-methylcyclopropyl)sulfonylcarbamoyl]-2,15-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-en-18-yl] 2,3-dihydro-1,4-benzodioxine-6-carboxylate —— C33H43N3O9S
    [(1S,4R,6S,7Z,11S,13R,18R)-11,13-dimethyl-4-[(1-methylcyclopropyl)sulfonylcarbamoyl]-2,15-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-en-18-yl] 2,3-dihydro-1,4-benzodioxine-6-carboxylate
    —— [(1S,4R,6S,7Z,13R,18R)-11,13-dimethyl-4-[(1-methylcyclopropyl)sulfonylcarbamoyl]-2,15-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-en-18-yl] N-(4-fluorophenyl)carbamate —— C31H41FN4O7S
    [(1S,4R,6S,7Z,13R,18R)-11,13-dimethyl-4-[(1-methylcyclopropyl)sulfonylcarbamoyl]-2,15-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-en-18-yl] N-(4-fluorophenyl)carbamate
    —— (1S,4R,6S,7Z,13R)-13-methyl-N-(1-methylcyclopropyl)sulfonyl-2,15-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide —— C23H35N3O5S
    (1S,4R,6S,7Z,13R)-13-methyl-N-(1-methylcyclopropyl)sulfonyl-2,15-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide
    —— [(1S,2R,3S,5S,6S,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,15,20-trimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosa-10,12,14(26),16,18-pentaen-6-yl] propanoate —— C32H43ClN2O10
    [(1S,2R,3S,5S,6S,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,15,20-trimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosa-10,12,14(26),16,18-pentaen-6-yl] propanoate
    —— [(1S,4R,6S,7Z,11R,13R,18R)-11,13-dimethyl-4-[(1-methylcyclopropyl)sulfonylcarbamoyl]-2,15-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-en-18-yl] N-[2-(trifluoromethyl)phenyl]carbamate —— C32H41F3N4O7S
    [(1S,4R,6S,7Z,11R,13R,18R)-11,13-dimethyl-4-[(1-methylcyclopropyl)sulfonylcarbamoyl]-2,15-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-en-18-yl] N-[2-(trifluoromethyl)phenyl]carbamate
    —— (2S)-6-amino-2-[(11-oxo-9-propan-2-yl-2,7-dioxa-10-azabicyclo[12.2.2]octadeca-1(16),14,17-trien-12-yl)sulfamoylamino]hexanoic acid —— C24H40N4O7S
    (2S)-6-amino-2-[(11-oxo-9-propan-2-yl-2,7-dioxa-10-azabicyclo[12.2.2]octadeca-1(16),14,17-trien-12-yl)sulfamoylamino]hexanoic acid
    —— 19-Amino-5-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-14-chloro-13-fluoro-3,8,16-trimethyl-17-oxa-4,5,8,20-tetrazatetracyclo[16.3.1.02,6.010,15]docosa-1(22),2(6),3,10(15),11,13,18,20-octaen-9-one —— C28H37ClFN5O3Si
    19-Amino-5-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-14-chloro-13-fluoro-3,8,16-trimethyl-17-oxa-4,5,8,20-tetrazatetracyclo[16.3.1.02,6.010,15]docosa-1(22),2(6),3,10(15),11,13,18,20-octaen-9-one
    —— [(1S,3S,5S,6S,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosa-10,12,14(26),16,18-pentaen-6-yl] (2S)-2-[methyl(3-sulfanylpropanoyl)amino]propanoate —— C35H48ClN3O10S
    [(1S,3S,5S,6S,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosa-10,12,14(26),16,18-pentaen-6-yl] (2S)-2-[methyl(3-sulfanylpropanoyl)amino]propanoate
    —— 6-[3-[3-[[(2S)-1-[[(1S,2R,3S,5S,6S,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosa-10,12,14(26),16,18-pentaen-6-yl]oxy]-1-oxopropan-2-yl]-methylamino]-3-oxopropyl]sulfanyl-2,5-dioxopyrrolidin-1-yl]hexanoic acid —— C45H61ClN4O14S
    6-[3-[3-[[(2S)-1-[[(1S,2R,3S,5S,6S,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosa-10,12,14(26),16,18-pentaen-6-yl]oxy]-1-oxopropan-2-yl]-methylamino]-3-oxopropyl]sulfanyl-2,5-dioxopyrrolidin-1-yl]hexanoic acid
    —— [(1S,3S,5S,6S,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosa-10,12,14(26),16,18-pentaen-6-yl] 2-methylpropanoate —— C32H43ClN2O9
    [(1S,3S,5S,6S,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosa-10,12,14(26),16,18-pentaen-6-yl] 2-methylpropanoate
    —— (14Z)-1-methyl-2-oxa-24-thia-7,9,23-triazabicyclo[19.2.1]tetracos-14-ene-8,22-dione —— C20H35N3O3S
    (14Z)-1-methyl-2-oxa-24-thia-7,9,23-triazabicyclo[19.2.1]tetracos-14-ene-8,22-dione
    —— (1S,4R,6S,7Z,11R,13R,18R)-11,13-dimethyl-N-(1-methylcyclopropyl)sulfonyl-2,15-dioxo-18-[2-(4-propan-2-yloxyphenyl)-6-pyrazin-2-ylpyridin-4-yl]oxy-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide —— C42H52N6O7S
    (1S,4R,6S,7Z,11R,13R,18R)-11,13-dimethyl-N-(1-methylcyclopropyl)sulfonyl-2,15-dioxo-18-[2-(4-propan-2-yloxyphenyl)-6-pyrazin-2-ylpyridin-4-yl]oxy-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide
    —— (1S,4R,6S,7Z,13R,18R)-18-imidazo[1,2-a]quinazolin-5-yloxy-11,13-dimethyl-N-(1-methylcyclopropyl)sulfonyl-2,15-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide —— C34H42N6O6S
    (1S,4R,6S,7Z,13R,18R)-18-imidazo[1,2-a]quinazolin-5-yloxy-11,13-dimethyl-N-(1-methylcyclopropyl)sulfonyl-2,15-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide
    —— (1S,4R,6S,7Z,11S,13R,18R)-11,13-dimethyl-N-(1-methylcyclopropyl)sulfonyl-2,15-dioxo-18-([1,2,4]triazolo[4,3-a]quinazolin-5-yloxy)-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide —— C33H41N7O6S
    (1S,4R,6S,7Z,11S,13R,18R)-11,13-dimethyl-N-(1-methylcyclopropyl)sulfonyl-2,15-dioxo-18-([1,2,4]triazolo[4,3-a]quinazolin-5-yloxy)-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide
    —— (1S,4R,6S,7Z,11S,13R,18R)-11,13-dimethyl-N-(1-methylcyclopropyl)sulfonyl-2,15-dioxo-18-[2-(4-propan-2-yloxyphenyl)-6-pyrazin-2-ylpyridin-4-yl]oxy-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide —— C42H52N6O7S
    (1S,4R,6S,7Z,11S,13R,18R)-11,13-dimethyl-N-(1-methylcyclopropyl)sulfonyl-2,15-dioxo-18-[2-(4-propan-2-yloxyphenyl)-6-pyrazin-2-ylpyridin-4-yl]oxy-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide
    —— (1S,4R,6S,7Z,11S,13R,18R)-11,13-dimethyl-N-(1-methylcyclopropyl)sulfonyl-2,15-dioxo-18-[2-(4-propan-2-yloxyphenyl)-6-(1,3-thiazol-2-yl)pyridin-4-yl]oxy-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide —— C41H51N5O7S2
    (1S,4R,6S,7Z,11S,13R,18R)-11,13-dimethyl-N-(1-methylcyclopropyl)sulfonyl-2,15-dioxo-18-[2-(4-propan-2-yloxyphenyl)-6-(1,3-thiazol-2-yl)pyridin-4-yl]oxy-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide
    —— (1S,4R,6S,7Z,11R,13R,18R)-18-hydroxy-11,13-dimethyl-N-(1-methylcyclopropyl)sulfonyl-2,15-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide —— C24H37N3O6S
    (1S,4R,6S,7Z,11R,13R,18R)-18-hydroxy-11,13-dimethyl-N-(1-methylcyclopropyl)sulfonyl-2,15-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide
    —— (1S,4R,6S,7Z,11S,13R)-11,13-dimethyl-N-(1-methylcyclopropyl)sulfonyl-2,15-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide —— C24H37N3O5S
    (1S,4R,6S,7Z,11S,13R)-11,13-dimethyl-N-(1-methylcyclopropyl)sulfonyl-2,15-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide
    —— (1S,4R,6S,7Z,11R,13R)-13-ethyl-11-methyl-N-(1-methylcyclopropyl)sulfonyl-2,15-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide —— C25H39N3O5S
    (1S,4R,6S,7Z,11R,13R)-13-ethyl-11-methyl-N-(1-methylcyclopropyl)sulfonyl-2,15-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide
    —— (1S,4R,6S,7Z,11R,13R,18R)-18-imidazo[1,2-a]quinazolin-5-yloxy-11,13-dimethyl-N-(1-methylcyclopropyl)sulfonyl-2,15-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide —— C34H42N6O6S
    (1S,4R,6S,7Z,11R,13R,18R)-18-imidazo[1,2-a]quinazolin-5-yloxy-11,13-dimethyl-N-(1-methylcyclopropyl)sulfonyl-2,15-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide
    —— (1S,4R,6S,7Z,11R,13R,18R)-11,13-dimethyl-N-(1-methylcyclopropyl)sulfonyl-2,15-dioxo-18-[2-(4-propan-2-yloxyphenyl)-6-(1,3-thiazol-2-yl)pyridin-4-yl]oxy-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide —— C41H51N5O7S2
    (1S,4R,6S,7Z,11R,13R,18R)-11,13-dimethyl-N-(1-methylcyclopropyl)sulfonyl-2,15-dioxo-18-[2-(4-propan-2-yloxyphenyl)-6-(1,3-thiazol-2-yl)pyridin-4-yl]oxy-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide
    —— (1S,4R,6S,7Z,11R,13R)-11,13-dimethyl-N-(1-methylcyclopropyl)sulfonyl-2,15-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide —— C24H37N3O5S
    (1S,4R,6S,7Z,11R,13R)-11,13-dimethyl-N-(1-methylcyclopropyl)sulfonyl-2,15-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide
    —— (1S,4R,6S,7Z,13R)-11,13-dimethyl-N-(1-methylcyclopropyl)sulfanyl-2,15-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide —— C24H37N3O3S
    (1S,4R,6S,7Z,13R)-11,13-dimethyl-N-(1-methylcyclopropyl)sulfanyl-2,15-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide
    —— (1S,4R,6S,7Z,13R,18R)-N-[1-(fluoromethyl)cyclopropyl]sulfonyl-18-hydroxy-11,13-dimethyl-2,15-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide —— C24H36FN3O6S
    (1S,4R,6S,7Z,13R,18R)-N-[1-(fluoromethyl)cyclopropyl]sulfonyl-18-hydroxy-11,13-dimethyl-2,15-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide
    —— (1S,4R,6S,7Z,11R,13S)-13-ethyl-11-methyl-N-(1-methylcyclopropyl)sulfonyl-2,15-dioxo-12-oxa-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide —— C24H37N3O6S
    (1S,4R,6S,7Z,11R,13S)-13-ethyl-11-methyl-N-(1-methylcyclopropyl)sulfonyl-2,15-dioxo-12-oxa-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide
    —— (1S,4R,6S,7Z,11R,13S)-11,13-dimethyl-N-[(R)-(1-methylcyclopropyl)sulfinyl]-2,15-dioxo-12-oxa-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide —— C23H35N3O5S
    (1S,4R,6S,7Z,11R,13S)-11,13-dimethyl-N-[(R)-(1-methylcyclopropyl)sulfinyl]-2,15-dioxo-12-oxa-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide
    —— (1S,4R,6S,7Z,11S,13R,18R)-18-hydroxy-11,13-dimethyl-N-(1-methylcyclopropyl)sulfonyl-2,15-dioxo-10-oxa-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide —— C23H35N3O7S
    (1S,4R,6S,7Z,11S,13R,18R)-18-hydroxy-11,13-dimethyl-N-(1-methylcyclopropyl)sulfonyl-2,15-dioxo-10-oxa-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide
    —— (1S,4R,6S,7Z,11R,13S)-11,13-dimethyl-N-(1-methylcyclopropyl)peroxy-2,15-dioxo-12-oxa-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide —— C23H35N3O6
    (1S,4R,6S,7Z,11R,13S)-11,13-dimethyl-N-(1-methylcyclopropyl)peroxy-2,15-dioxo-12-oxa-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide
    —— (1S,4R,6S,7Z,11R,13S,18R)-13-ethyl-18-(7-fluoro-6-methoxyisoquinolin-1-yl)oxy-11-methyl-N-(1-methylcyclopropyl)sulfonyl-2,15-dioxo-12-oxa-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide —— C34H43FN4O8S
    (1S,4R,6S,7Z,11R,13S,18R)-13-ethyl-18-(7-fluoro-6-methoxyisoquinolin-1-yl)oxy-11-methyl-N-(1-methylcyclopropyl)sulfonyl-2,15-dioxo-12-oxa-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide
    —— tert-butyl-[(8S,11R)-3,10-dioxo-8-propan-2-yl-6-oxa-2,9-diazabicyclo[11.2.2]heptadeca-1(15),13,16-trien-11-yl]carbamic acid —— C22H33N3O5
    tert-butyl-[(8S,11R)-3,10-dioxo-8-propan-2-yl-6-oxa-2,9-diazabicyclo[11.2.2]heptadeca-1(15),13,16-trien-11-yl]carbamic acid
    —— [(15R,19S)-19-(cyclopropylsulfonylcarbamoyl)-15-(3-naphthalen-1-ylquinoxalin-2-yl)oxy-12,17-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadeca-2,4(6)-dien-11-yl]carbamic acid —— C40H40N6O8S
    [(15R,19S)-19-(cyclopropylsulfonylcarbamoyl)-15-(3-naphthalen-1-ylquinoxalin-2-yl)oxy-12,17-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadeca-2,4(6)-dien-11-yl]carbamic acid
    —— (1S,6S,7E,14R,18R)-N-cyclopropylsulfonyl-18-[7-methoxy-8-methyl-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-4-yl]oxy-2,15-dioxo-14-[2-oxo-2-[4-(trifluoromethyl)piperidin-1-yl]ethyl]-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide —— C46H58F3N7O8S2
    (1S,6S,7E,14R,18R)-N-cyclopropylsulfonyl-18-[7-methoxy-8-methyl-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-4-yl]oxy-2,15-dioxo-14-[2-oxo-2-[4-(trifluoromethyl)piperidin-1-yl]ethyl]-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide
    —— (1S,4R,7Z,14R,18R)-N-cyclopropylsulfonyl-14-[2-(3,3-difluorocyclohexyl)-2-oxoethyl]-18-[7-methoxy-8-methyl-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-4-yl]oxy-2,15-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide —— C46H58F2N6O8S2
    (1S,4R,7Z,14R,18R)-N-cyclopropylsulfonyl-14-[2-(3,3-difluorocyclohexyl)-2-oxoethyl]-18-[7-methoxy-8-methyl-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-4-yl]oxy-2,15-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide
    —— (5R)-3-[(1S,7Z,18R)-4-(cyclopropylsulfonylcarbamoyl)-2-oxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-en-18-yl]-7-fluoro-6-oxo-5-(2-oxo-2-piperidin-1-ylethyl)-3,5-dihydro-1H-isoindole-2-carboxylic acid —— C37H50FN5O8S
    (5R)-3-[(1S,7Z,18R)-4-(cyclopropylsulfonylcarbamoyl)-2-oxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-en-18-yl]-7-fluoro-6-oxo-5-(2-oxo-2-piperidin-1-ylethyl)-3,5-dihydro-1H-isoindole-2-carboxylic acid
    —— (6R)-1-[(1S,4R,7Z,18R)-4-(cyclopropylsulfonylcarbamoyl)-2-oxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-en-18-yl]-6-[2-(3,3-difluoropyrrolidin-1-yl)-2-oxoethyl]-5-oxo-1,3,4,6-tetrahydroisoquinoline-2-carboxylic acid —— C37H49F2N5O8S
    (6R)-1-[(1S,4R,7Z,18R)-4-(cyclopropylsulfonylcarbamoyl)-2-oxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-en-18-yl]-6-[2-(3,3-difluoropyrrolidin-1-yl)-2-oxoethyl]-5-oxo-1,3,4,6-tetrahydroisoquinoline-2-carboxylic acid
    —— (6R)-1-[(1S,4R,7Z,18R)-4-(cyclopropylsulfonylcarbamoyl)-2-oxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-en-18-yl]-6-[2-(3,3-difluoropiperidin-1-yl)-2-oxoethyl]-5-oxo-1,3,4,6-tetrahydroisoquinoline-2-carboxylic acid —— C38H51F2N5O8S
    (6R)-1-[(1S,4R,7Z,18R)-4-(cyclopropylsulfonylcarbamoyl)-2-oxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-en-18-yl]-6-[2-(3,3-difluoropiperidin-1-yl)-2-oxoethyl]-5-oxo-1,3,4,6-tetrahydroisoquinoline-2-carboxylic acid
    —— (1S,6S,7Z,14R,18R)-N-cyclopropylsulfonyl-18-[7-methoxy-8-methyl-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-4-yl]oxy-2,15-dioxo-14-[2-oxo-2-[4-(trifluoromethyl)piperidin-1-yl]ethyl]-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide —— C46H58F3N7O8S2
    (1S,6S,7Z,14R,18R)-N-cyclopropylsulfonyl-18-[7-methoxy-8-methyl-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-4-yl]oxy-2,15-dioxo-14-[2-oxo-2-[4-(trifluoromethyl)piperidin-1-yl]ethyl]-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide
    —— 1-[(1S,4R,7E,14R,18R)-4-(cyclopropylsulfonylcarbamoyl)-2,15-dioxo-14-(2-oxo-2-piperidin-1-ylethyl)-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-en-18-yl]-3,4-dihydro-1H-isoquinoline-2-carboxylic acid —— C38H51N5O8S
    1-[(1S,4R,7E,14R,18R)-4-(cyclopropylsulfonylcarbamoyl)-2,15-dioxo-14-(2-oxo-2-piperidin-1-ylethyl)-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-en-18-yl]-3,4-dihydro-1H-isoquinoline-2-carboxylic acid
    —— 1-[(1S,7Z,14R,18R)-4-(cyclopropylsulfonylcarbamoyl)-2,15-dioxo-14-(2-oxo-2-piperidin-1-ylethyl)-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-en-18-yl]-4-fluoro-1,3-dihydroisoindole-2-carboxylic acid —— C37H48FN5O8S
    1-[(1S,7Z,14R,18R)-4-(cyclopropylsulfonylcarbamoyl)-2,15-dioxo-14-(2-oxo-2-piperidin-1-ylethyl)-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-en-18-yl]-4-fluoro-1,3-dihydroisoindole-2-carboxylic acid
    —— (1S,4R,6S,7E,14R,18R)-N-cyclopropylsulfonyl-18-(7-methoxy-2-pyridin-2-ylquinolin-4-yl)oxy-2,15-dioxo-14-(2-oxo-2-piperidin-1-ylethyl)-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide —— C43H52N6O8S
    (1S,4R,6S,7E,14R,18R)-N-cyclopropylsulfonyl-18-(7-methoxy-2-pyridin-2-ylquinolin-4-yl)oxy-2,15-dioxo-14-(2-oxo-2-piperidin-1-ylethyl)-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide
    —— 1-[(1S,4R,7Z,14R,18R)-4-(cyclopropylsulfonylcarbamoyl)-14-[2-(3,3-difluoropyrrolidin-1-yl)-2-oxoethyl]-2,15-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-en-18-yl]-3,4-dihydro-1H-isoquinoline-2-carboxylic acid —— C37H47F2N5O8S
    1-[(1S,4R,7Z,14R,18R)-4-(cyclopropylsulfonylcarbamoyl)-14-[2-(3,3-difluoropyrrolidin-1-yl)-2-oxoethyl]-2,15-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-en-18-yl]-3,4-dihydro-1H-isoquinoline-2-carboxylic acid
    —— (1S,4R,7E,14R,18R)-N-cyclopropylsulfonyl-2,15-dioxo-14-[2-oxo-2-[4-(trifluoromethyl)piperidin-1-yl]ethyl]-18-[(2-pyridin-2-yl-8,9-dihydrofuro[2,3-h]quinolin-4-yl)oxy]-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide —— C45H51F3N6O8S
    (1S,4R,7E,14R,18R)-N-cyclopropylsulfonyl-2,15-dioxo-14-[2-oxo-2-[4-(trifluoromethyl)piperidin-1-yl]ethyl]-18-[(2-pyridin-2-yl-8,9-dihydrofuro[2,3-h]quinolin-4-yl)oxy]-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide
    —— 1-[(1S,7E,14R,18R)-4-(cyclopropylsulfonylcarbamoyl)-2,15-dioxo-14-(2-oxo-2-piperidin-1-ylethyl)-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-en-18-yl]-4-fluoro-1,3-dihydroisoindole-2-carboxylic acid —— C37H48FN5O8S
    1-[(1S,7E,14R,18R)-4-(cyclopropylsulfonylcarbamoyl)-2,15-dioxo-14-(2-oxo-2-piperidin-1-ylethyl)-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-en-18-yl]-4-fluoro-1,3-dihydroisoindole-2-carboxylic acid
    —— (6R)-1-[(1S,4R,7Z,18R)-4-(cyclopropylsulfonylcarbamoyl)-2-oxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-en-18-yl]-5-oxo-6-(2-oxo-2-piperidin-1-ylethyl)-1,3,4,6-tetrahydroisoquinoline-2-carboxylic acid —— C38H53N5O8S
    (6R)-1-[(1S,4R,7Z,18R)-4-(cyclopropylsulfonylcarbamoyl)-2-oxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-en-18-yl]-5-oxo-6-(2-oxo-2-piperidin-1-ylethyl)-1,3,4,6-tetrahydroisoquinoline-2-carboxylic acid
    —— (1S,4R,7Z,14R,18R)-N-cyclopropylsulfonyl-2,15-dioxo-14-[2-oxo-2-[4-(trifluoromethyl)piperidin-1-yl]ethyl]-18-[(2-pyridin-2-yl-8,9-dihydrofuro[2,3-h]quinolin-4-yl)oxy]-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide —— C45H51F3N6O8S
    (1S,4R,7Z,14R,18R)-N-cyclopropylsulfonyl-2,15-dioxo-14-[2-oxo-2-[4-(trifluoromethyl)piperidin-1-yl]ethyl]-18-[(2-pyridin-2-yl-8,9-dihydrofuro[2,3-h]quinolin-4-yl)oxy]-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide
    —— 2-[(1S,4R,7Z,14R,18R)-18-(8-chloro-7-methoxy-2-pyridin-2-ylquinolin-4-yl)oxy-4-(cyclopropylsulfonylcarbamoyl)-2,15-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-en-14-yl]acetic acid —— C38H42ClN5O9S
    2-[(1S,4R,7Z,14R,18R)-18-(8-chloro-7-methoxy-2-pyridin-2-ylquinolin-4-yl)oxy-4-(cyclopropylsulfonylcarbamoyl)-2,15-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-en-14-yl]acetic acid
    —— 2-[(1S,4R,7E,14R,18R)-18-(8-chloro-7-methoxy-2-pyridin-2-ylquinolin-4-yl)oxy-4-(cyclopropylsulfonylcarbamoyl)-2,15-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-en-14-yl]acetic acid —— C38H42ClN5O9S
    2-[(1S,4R,7E,14R,18R)-18-(8-chloro-7-methoxy-2-pyridin-2-ylquinolin-4-yl)oxy-4-(cyclopropylsulfonylcarbamoyl)-2,15-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-en-14-yl]acetic acid
    —— 1-[(1S,4R,7E,14R,18R)-4-(cyclopropylsulfonylcarbamoyl)-14-[2-(3,3-difluoropiperidin-1-yl)-2-oxoethyl]-2,15-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-en-18-yl]-3,4-dihydro-1H-isoquinoline-2-carboxylic acid —— C38H49F2N5O8S
    1-[(1S,4R,7E,14R,18R)-4-(cyclopropylsulfonylcarbamoyl)-14-[2-(3,3-difluoropiperidin-1-yl)-2-oxoethyl]-2,15-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-en-18-yl]-3,4-dihydro-1H-isoquinoline-2-carboxylic acid
    —— 1-[(1S,4R,7Z,14R,18R)-4-(cyclopropylsulfonylcarbamoyl)-14-[2-(3,3-difluoropiperidin-1-yl)-2-oxoethyl]-2,15-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-en-18-yl]-3,4-dihydro-1H-isoquinoline-2-carboxylic acid —— C38H49F2N5O8S
    1-[(1S,4R,7Z,14R,18R)-4-(cyclopropylsulfonylcarbamoyl)-14-[2-(3,3-difluoropiperidin-1-yl)-2-oxoethyl]-2,15-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-en-18-yl]-3,4-dihydro-1H-isoquinoline-2-carboxylic acid