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    首页 分子通 按分子结构分类 有机化合物 苯丙烷和聚酮 大环内酰胺类

    大环内酰胺类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— (12Z,22Z,42Z,52Z)-15-(2-(dimethylamino)ethyl)-7,11-diaza-1,4,5(2,4),2(4,2)-tetraoxazola-3(2,6)-pyridina-9(1,3)-benzenacyclododecaphane-6,12-dione 1577289-05-4 C31H26N8O6
    (12Z,22Z,42Z,52Z)-15-(2-(dimethylamino)ethyl)-7,11-diaza-1,4,5(2,4),2(4,2)-tetraoxazola-3(2,6)-pyridina-9(1,3)-benzenacyclododecaphane-6,12-dione
    —— 2,9-dioxo-1,4,7,10-tetraaza-4,7-cyclododecanediacetic acid 93031-55-1 C12H20N4O6
    2,9-dioxo-1,4,7,10-tetraaza-4,7-cyclododecanediacetic acid
    —— N<sup>2</sup>'-deacetyl-N<sup>2</sup>'-(3-methylthio-1-oxopropyl)maytansine 912569-84-7 C36H50ClN3O10S
    N<sup>2</sup>'-deacetyl-N<sup>2</sup>'-(3-methylthio-1-oxopropyl)maytansine
    —— Lys-MCC-MDC 1281816-04-3 C53H75ClN6O15S
    Lys-MCC-MDC
    —— rifamycin Verde 72428-95-6 C39H46N2O12S
    rifamycin Verde
    —— 17-[2-(dimethylamino)ethylamino]-11-oxo-17-demethyoxygeldanamycin 497860-87-4 C32H46N4O8
    17-[2-(dimethylamino)ethylamino]-11-oxo-17-demethyoxygeldanamycin
    —— S-[(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl] (2R)-2-hydroxy-2-[(2R,7Z,9E,12R,13E,17R,20S)-12-hydroxy-2,14-dimethyl-11,19,20-trioxo-4,20lambda4-dithia-1,21-diazatricyclo[15.2.1.13,6]henicosa-3(21),5,7,9,13-pentaen-17-yl]propanethioate 186643-06-1 C27H30N2O9S3
    S-[(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl] (2R)-2-hydroxy-2-[(2R,7Z,9E,12R,13E,17R,20S)-12-hydroxy-2,14-dimethyl-11,19,20-trioxo-4,20lambda4-dithia-1,21-diazatricyclo[15.2.1.13,6]henicosa-3(21),5,7,9,13-pentaen-17-yl]propanethioate
    —— S-deoxyleinamycin 127183-14-6 C22H26N2O5S3
    S-deoxyleinamycin
    —— (2R,4'R,6R,9E,11R,13E,15Z)-4'-hydroxy-11-(methoxymethoxy)-2,4',9-trimethylspiro[19-thia-3,20-diazabicyclo[15.2.1]icosa-1(20),9,13,15,17-pentaene-6,5'-dithiolane]-3',4,12-trione 150021-51-5 C24H30N2O6S3
    (2R,4'R,6R,9E,11R,13E,15Z)-4'-hydroxy-11-(methoxymethoxy)-2,4',9-trimethylspiro[19-thia-3,20-diazabicyclo[15.2.1]icosa-1(20),9,13,15,17-pentaene-6,5'-dithiolane]-3',4,12-trione
    —— (1S,4R,6S,7Z,14S,18R)-14-isocyanato-18-(7-methoxy-8-methyl-2-propan-2-yloxyquinolin-4-yl)oxy-N-(1-methylcyclopropyl)sulfonyl-2,15-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide 1309889-06-2 C37H47N5O9S
    (1S,4R,6S,7Z,14S,18R)-14-isocyanato-18-(7-methoxy-8-methyl-2-propan-2-yloxyquinolin-4-yl)oxy-N-(1-methylcyclopropyl)sulfonyl-2,15-dioxo-3,16-diazatricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxamide
    —— (8S,9R)-7,8-dimethyl-9-phenyl-10-oxa-1,7,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-6-one 1267640-07-2 C18H24N4O2
    (8S,9R)-7,8-dimethyl-9-phenyl-10-oxa-1,7,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-6-one
    —— (7S,8R)-6,7-dimethyl-8-phenyl-9-oxa-1,6,12,13-tetrazabicyclo[9.2.1]tetradeca-11(14),12-dien-5-one 1267640-05-0 C17H22N4O2
    (7S,8R)-6,7-dimethyl-8-phenyl-9-oxa-1,6,12,13-tetrazabicyclo[9.2.1]tetradeca-11(14),12-dien-5-one
    —— (24S,25R)-20-[(4-methoxyphenyl)methyl]-23,24-dimethyl-25-phenyl-4,26-dioxa-1,7,17,20,23,29,30-heptazatricyclo[26.2.1.010,15]hentriaconta-10,12,14,28(31),29-pentaene-8,18,22-trione 1351948-98-5 C38H47N7O6
    (24S,25R)-20-[(4-methoxyphenyl)methyl]-23,24-dimethyl-25-phenyl-4,26-dioxa-1,7,17,20,23,29,30-heptazatricyclo[26.2.1.010,15]hentriaconta-10,12,14,28(31),29-pentaene-8,18,22-trione
    —— (17R,18S)-22-[(4-methoxyphenyl)methyl]-18,19-dimethyl-17-phenyl-2,8,16-trioxa-5,11,12,13,19,22,25-heptazatricyclo[26.2.2.111,14]tritriaconta-1(31),12,14(33),28(32),29-pentaene-4,20,24-trione 1351949-01-3 C39H49N7O7
    (17R,18S)-22-[(4-methoxyphenyl)methyl]-18,19-dimethyl-17-phenyl-2,8,16-trioxa-5,11,12,13,19,22,25-heptazatricyclo[26.2.2.111,14]tritriaconta-1(31),12,14(33),28(32),29-pentaene-4,20,24-trione
    —— (17R,18S,21R)-18,19,21-trimethyl-17-phenyl-2,8,16-trioxa-5,11,12,13,19,24-hexazatricyclo[25.2.2.111,14]dotriaconta-1(30),12,14(32),27(31),28-pentaene-4,20,23-trione 1351948-95-2 C32H42N6O6
    (17R,18S,21R)-18,19,21-trimethyl-17-phenyl-2,8,16-trioxa-5,11,12,13,19,24-hexazatricyclo[25.2.2.111,14]dotriaconta-1(30),12,14(32),27(31),28-pentaene-4,20,23-trione
    —— (9S,10R)-8,9-dimethyl-10-phenyl-11-oxa-1,8,14,15-tetrazabicyclo[11.2.1]hexadeca-13(16),14-dien-7-one 1267640-10-7 C19H26N4O2
    (9S,10R)-8,9-dimethyl-10-phenyl-11-oxa-1,8,14,15-tetrazabicyclo[11.2.1]hexadeca-13(16),14-dien-7-one
    —— 3,4:12,13-dibenzo-2,5,11,14-tetraoxo-1,6,10,15-tetraazacyclooctadecane 37493-55-3 C22H24N4O4
    3,4:12,13-dibenzo-2,5,11,14-tetraoxo-1,6,10,15-tetraazacyclooctadecane
    —— (2S,4E,6R,8S)-8-hydroxy-2,4,6-trimethyl-4-nonenoyl-(S)-alanyl-N-methyl-2-bromo-(R)-tryptophanyl-O-tert-butyldimethylsilyl-(R)-β-tyrosine ρ-lactone 161722-19-6 C42H59BrN4O6Si
    (2S,4E,6R,8S)-8-hydroxy-2,4,6-trimethyl-4-nonenoyl-(S)-alanyl-N-methyl-2-bromo-(R)-tryptophanyl-O-tert-butyldimethylsilyl-(R)-β-tyrosine ρ-lactone
    —— jasplakinolide 102396-24-7 C36H45BrN4O6
    jasplakinolide
    —— rifamycin sodium 14897-39-3 C37H46NO12*Na
    rifamycin sodium
    —— [(4E,6Z,8S,9S,10E,12S,13R,14S,16R)-19-[5-[[4-[(2,2-difluorocyclooct-3-yn-1-yl)methyl]benzoyl]amino]pentylamino]-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl] carbamate 1236153-36-8 C49H64F2N4O9
    [(4E,6Z,8S,9S,10E,12S,13R,14S,16R)-19-[5-[[4-[(2,2-difluorocyclooct-3-yn-1-yl)methyl]benzoyl]amino]pentylamino]-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl] carbamate
    —— rifamycin L —— C39H49NO14
    rifamycin L
    —— BATA-MC 1312718-51-6 C30H37N5O4
    BATA-MC
    —— (2R)-1-[1-[2-[(18S,25S,35S)-35-[(S)-hydroxy(phenyl)methyl]-28-(methoxymethyl)-21-methyl-18-[2-(methylamino)-2-oxoethyl]-16,23,30,33-tetraoxo-25-propan-2-yl-3,13,20,27,37-pentathia-7,17,24,31,34,39,40,41,42,43-decazaheptacyclo[34.2.1.12,5.112,15.119,22.126,29.06,11]tritetraconta-1(38),2(43),4,6(11),7,9,12(42),14,19(41),21,26(40),28,36(39)-tridecaen-8-yl]-1,3-thiazol-4-yl]imidazole-4-carbonyl]pyrrolidine-2-carboxylic acid 960062-08-2 C56H53N15O10S6
    (2R)-1-[1-[2-[(18S,25S,35S)-35-[(S)-hydroxy(phenyl)methyl]-28-(methoxymethyl)-21-methyl-18-[2-(methylamino)-2-oxoethyl]-16,23,30,33-tetraoxo-25-propan-2-yl-3,13,20,27,37-pentathia-7,17,24,31,34,39,40,41,42,43-decazaheptacyclo[34.2.1.12,5.112,15.119,22.126,29.06,11]tritetraconta-1(38),2(43),4,6(11),7,9,12(42),14,19(41),21,26(40),28,36(39)-tridecaen-8-yl]-1,3-thiazol-4-yl]imidazole-4-carbonyl]pyrrolidine-2-carboxylic acid
    —— 6-((2-(1,4,8,11-tetraazacyclotetradecan-1-yl)ethyl)amino)-2-methyl-1H-benzo[de]isoquinoline-1,3(2H)-dione 1207670-51-6 C25H36N6O2
    6-((2-(1,4,8,11-tetraazacyclotetradecan-1-yl)ethyl)amino)-2-methyl-1H-benzo[de]isoquinoline-1,3(2H)-dione
    —— 6-((2-(1,4,8,11-tetraazacyclotetradecan-1-yl)ethyl)amino)-2-octyl-1H-benzo[de]isoquinoline-1,3(2H)-dione 1207670-49-2 C32H50N6O2
    6-((2-(1,4,8,11-tetraazacyclotetradecan-1-yl)ethyl)amino)-2-octyl-1H-benzo[de]isoquinoline-1,3(2H)-dione
    —— ethyl (1R,4R,6S,7Z,15R,17S)-17-[7-methoxy-8-methyl-2-(4-propan-2-yl-1,3-thiazol-2-yl)quinolin-4-yl]oxy-13-methyl-2,14-dioxo-3-(2,2,2-trifluoroacetyl)-3,13-diazatricyclo[13.3.0.04,6]octadec-7-ene-4-carboxylate 1431935-29-3 C39H45F3N4O7S
    ethyl (1R,4R,6S,7Z,15R,17S)-17-[7-methoxy-8-methyl-2-(4-propan-2-yl-1,3-thiazol-2-yl)quinolin-4-yl]oxy-13-methyl-2,14-dioxo-3-(2,2,2-trifluoroacetyl)-3,13-diazatricyclo[13.3.0.04,6]octadec-7-ene-4-carboxylate
    —— ethyl (1R,4R,6S,7Z,15R,17S)-3-(2-chloro-2,2-difluoroacetyl)-17-[7-methoxy-8-methyl-2-(4-propan-2-yl-1,3-thiazol-2-yl)quinolin-4-yl]oxy-13-methyl-2,14-dioxo-3,13-diazatricyclo[13.3.0.04,6]octadec-7-ene-4-carboxylate 1431935-30-6 C39H45ClF2N4O7S
    ethyl (1R,4R,6S,7Z,15R,17S)-3-(2-chloro-2,2-difluoroacetyl)-17-[7-methoxy-8-methyl-2-(4-propan-2-yl-1,3-thiazol-2-yl)quinolin-4-yl]oxy-13-methyl-2,14-dioxo-3,13-diazatricyclo[13.3.0.04,6]octadec-7-ene-4-carboxylate
    —— TNP-2092 922717-97-3 C65H81FN6O15
    TNP-2092
    —— 21-hydroxy-4,7,10,13,16,19-hexaoxa-1-azatricyclo[19.7.0.022,27]octacosa-22,24,26-trien-28-one 174468-49-6 C21H31NO8
    21-hydroxy-4,7,10,13,16,19-hexaoxa-1-azatricyclo[19.7.0.022,27]octacosa-22,24,26-trien-28-one
    —— N,N'-Diacetylinandenin-10-ol 122890-21-5 C27H51N3O4
    N,N'-Diacetylinandenin-10-ol
    —— (4S,17E)-23-hydroxy-21-methoxy-4-methyl-3-oxa-9,14-diazabicyclo[17.4.0]tricosa-1(19),17,20,22-tetraene-2,8,15-trione 1200112-11-3 C22H30N2O6
    (4S,17E)-23-hydroxy-21-methoxy-4-methyl-3-oxa-9,14-diazabicyclo[17.4.0]tricosa-1(19),17,20,22-tetraene-2,8,15-trione
    —— 7,12-diaza-1-sulfoxo-4,15-dioxa-19,23-dimethyl-2,3;16,17-dibenzocycloheptadecane-6,13-dione 1023710-04-4 C22H26N2O5S
    7,12-diaza-1-sulfoxo-4,15-dioxa-19,23-dimethyl-2,3;16,17-dibenzocycloheptadecane-6,13-dione
    —— methyl (8S,17S,19S)-17-amino-24-fluoro-6,14-dioxo-10,21-dioxa-4-thia-7,15-diazatetracyclo[20.3.1.1<sup>2</sup>'<sup>5</sup>.0<sup>15</sup>'<sup>19</sup>]heptacosa-1(26),2,5(27),22,24-pentaene-8-carboxylate 1460307-90-7 C24H28FN3O6S
    methyl (8S,17S,19S)-17-amino-24-fluoro-6,14-dioxo-10,21-dioxa-4-thia-7,15-diazatetracyclo[20.3.1.1<sup>2</sup>'<sup>5</sup>.0<sup>15</sup>'<sup>19</sup>]heptacosa-1(26),2,5(27),22,24-pentaene-8-carboxylate
    —— methyl (8S,17S,19S)-24-fluoro-6,14-dioxo-17-[(2-phenylacetyl)amino]-10,21-dioxa-4-thia-7,15-diazatetracyclo[20.3.1.1<sup>2,5</sup>.0<sup>15,19</sup>]heptacosa-1(26),2,5(27),22,24-pentaene-8-carboxylate 1460303-90-5 C32H34FN3O7S
    methyl (8S,17S,19S)-24-fluoro-6,14-dioxo-17-[(2-phenylacetyl)amino]-10,21-dioxa-4-thia-7,15-diazatetracyclo[20.3.1.1<sup>2,5</sup>.0<sup>15,19</sup>]heptacosa-1(26),2,5(27),22,24-pentaene-8-carboxylate
    —— (2S,11S,19aS)-2-(acetylamino)-15-fluoro-N-[2-(1H-indol-3-yl)ethyl]-7,12-dimethyl-5,8,13-trioxo-2,3,6,7,8,9,10,11,12,13,19,19a-dodecahydro-1H,5H-pyrrolo[2,1-c][1,4,7,12]benzoxatriazacyclopentadecine-11-carboxamide 1264224-58-9 C33H39FN6O6
    (2S,11S,19aS)-2-(acetylamino)-15-fluoro-N-[2-(1H-indol-3-yl)ethyl]-7,12-dimethyl-5,8,13-trioxo-2,3,6,7,8,9,10,11,12,13,19,19a-dodecahydro-1H,5H-pyrrolo[2,1-c][1,4,7,12]benzoxatriazacyclopentadecine-11-carboxamide
    —— benzyl (2S,11S,19aS)-2-(acetylamino)-15-fluoro-7,12-dimethyl-5,8,13-trioxo-2,3,6,7,8,9,10,11,12,13,19,19a-dodecahydro-1H,5H-pyrrolo[2,1-c][1,4,7,12]benzoxatriazacyclopentadecine-11-carboxylate 1264224-46-5 C30H35FN4O7
    benzyl (2S,11S,19aS)-2-(acetylamino)-15-fluoro-7,12-dimethyl-5,8,13-trioxo-2,3,6,7,8,9,10,11,12,13,19,19a-dodecahydro-1H,5H-pyrrolo[2,1-c][1,4,7,12]benzoxatriazacyclopentadecine-11-carboxylate
    —— Rifampicin 13292-46-1 C43H58N4O12
    Rifampicin
    —— 19-Amino-13-fluoro-3,5,8,16-tetramethyl-17-oxa-4,5,8,20,22-pentazatetracyclo[16.3.1.02,6.010,15]docosa-1(21),2(6),3,10(15),11,13,18(22),19-octaen-9-one 1454846-70-8 C20H21FN6O2
    19-Amino-13-fluoro-3,5,8,16-tetramethyl-17-oxa-4,5,8,20,22-pentazatetracyclo[16.3.1.02,6.010,15]docosa-1(21),2(6),3,10(15),11,13,18(22),19-octaen-9-one
    —— 19-Amino-13-fluoro-3,5,8,16-tetramethyl-17-oxa-4,5,8,20-tetrazatetracyclo[16.3.1.02,6.010,15]docosa-1(22),2(6),3,10(15),11,13,18,20-octaen-9-one 1454846-48-0 C21H22FN5O2
    19-Amino-13-fluoro-3,5,8,16-tetramethyl-17-oxa-4,5,8,20-tetrazatetracyclo[16.3.1.02,6.010,15]docosa-1(22),2(6),3,10(15),11,13,18,20-octaen-9-one
    —— maytansinol —— C28H37ClN2O8
    maytansinol
    —— dibanzo-1,5,9,13-tetraaza-2,10-dioxo-4,12-diphenylcyclohexadecane 1075689-94-9 C30H28N4O2
    dibanzo-1,5,9,13-tetraaza-2,10-dioxo-4,12-diphenylcyclohexadecane
    —— desacetylvicibactin 1193340-45-2 C27H48N6O12
    desacetylvicibactin
    —— 8-Fluoro-26-hydroxy-18-methyl-16-oxa-3,18,24,27-tetrazatetracyclo[17.7.2.05,10.024,28]octacosa-1(26),5(10),6,8,27-pentaene-2,17,25-trione 1538554-40-3 C24H29FN4O5
    8-Fluoro-26-hydroxy-18-methyl-16-oxa-3,18,24,27-tetrazatetracyclo[17.7.2.05,10.024,28]octacosa-1(26),5(10),6,8,27-pentaene-2,17,25-trione
    —— tert-butyl N-[(10R,11E,14S)-5-[(methoxycarbonyl)amino]-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18-triazatricyclo[13.2.1.0<sup>2</sup>'<sup>7</sup>]octadeca-1(17),2,4,6,11,15(18)-hexaen-14-yl]carbamate 1422388-59-7 C29H43N5O6Si
    tert-butyl N-[(10R,11E,14S)-5-[(methoxycarbonyl)amino]-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18-triazatricyclo[13.2.1.0<sup>2</sup>'<sup>7</sup>]octadeca-1(17),2,4,6,11,15(18)-hexaen-14-yl]carbamate
    —— tert-butyl N-[(10S,11E,14S)-5-[(methoxycarbonyl)amino]-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18-triazatricyclo[13.2.1.0<sup>2</sup>'<sup>7</sup>]octadeca-1(17),2,4,6,11,15(18)-hexaen-14-yl]carbamate 1422388-60-0 C29H43N5O6Si
    tert-butyl N-[(10S,11E,14S)-5-[(methoxycarbonyl)amino]-10-methyl-9-oxo-16-{[2-(trimethylsilyl)ethoxy]methyl}-8,16,18-triazatricyclo[13.2.1.0<sup>2</sup>'<sup>7</sup>]octadeca-1(17),2,4,6,11,15(18)-hexaen-14-yl]carbamate
    —— Pyridin-3-ylmethyl 12-chloro-20,20-dimethyl-23-oxo-5-(2,2,2-trifluoroethoxy)-14-oxa-2,4,6,8,18,22,31-heptazatetracyclo[22.2.2.210,13.13,7]hentriaconta-1(26),3,5,7(31),10,12,24,27,29-nonaene-18-carboxylate 1622009-11-3 C34H36ClF3N8O5
    Pyridin-3-ylmethyl 12-chloro-20,20-dimethyl-23-oxo-5-(2,2,2-trifluoroethoxy)-14-oxa-2,4,6,8,18,22,31-heptazatetracyclo[22.2.2.210,13.13,7]hentriaconta-1(26),3,5,7(31),10,12,24,27,29-nonaene-18-carboxylate
    —— (4-Nitrophenyl) 12-chloro-20,20-dimethyl-23-oxo-5-(2,2,2-trifluoroethoxy)-14-oxa-2,4,6,8,18,22,31-heptazatetracyclo[22.2.2.210,13.13,7]hentriaconta-1(26),3,5,7(31),10,12,24,27,29-nonaene-18-carboxylate 1622008-98-3 C34H34ClF3N8O7
    (4-Nitrophenyl) 12-chloro-20,20-dimethyl-23-oxo-5-(2,2,2-trifluoroethoxy)-14-oxa-2,4,6,8,18,22,31-heptazatetracyclo[22.2.2.210,13.13,7]hentriaconta-1(26),3,5,7(31),10,12,24,27,29-nonaene-18-carboxylate
    —— N-[(10S,12S,16S)-16-amino-20-methyl-15,21-dioxo-8-oxa-14,20-diazatetracyclo[20.3.1.0<sup>2</sup>'<sup>7</sup>.0<sup>10</sup>'<sup>14</sup>]hexacosa-1(26),2,4,6,22,24-hexaen-12-yl]-2-(2-naphthyl)acetamide 1460301-55-6 C36H38N4O4
    N-[(10S,12S,16S)-16-amino-20-methyl-15,21-dioxo-8-oxa-14,20-diazatetracyclo[20.3.1.0<sup>2</sup>'<sup>7</sup>.0<sup>10</sup>'<sup>14</sup>]hexacosa-1(26),2,4,6,22,24-hexaen-12-yl]-2-(2-naphthyl)acetamide
    —— tert-butyl N-[(9S,11R)-14,20-dioxo-7-oxa-13,16,19,23-tetraazatetracyclo[19.3.1.1<sup>2,6</sup>.0<sup>9,13</sup>]hexacosa-1(25),2(26),3,5,21,23-hexaen-11-yl]carbamate 1460302-36-6 C26H33N5O5
    tert-butyl N-[(9S,11R)-14,20-dioxo-7-oxa-13,16,19,23-tetraazatetracyclo[19.3.1.1<sup>2,6</sup>.0<sup>9,13</sup>]hexacosa-1(25),2(26),3,5,21,23-hexaen-11-yl]carbamate