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大环内酰胺类

中文名称 英文名称 CAS号 化学式 结构式图片
—— 11-benzyl-6-[2-[3-(hydroxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-3-phenyl-1-oxa-4-azacyclododec-8-ene-5,12-dione —— C35H38N2O5
11-benzyl-6-[2-[3-(hydroxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-3-phenyl-1-oxa-4-azacyclododec-8-ene-5,12-dione
—— 3-(benzylsulfanylmethyl)-6-[2-[3-(hydroxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-1-oxa-4-azacyclododec-8-ene-5,12-dione —— C30H36N2O5S
3-(benzylsulfanylmethyl)-6-[2-[3-(hydroxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-1-oxa-4-azacyclododec-8-ene-5,12-dione
—— benzyl N-[6-[2-[3-(hydroxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-5,12-dioxo-3-phenyl-1-oxa-4-azacyclododec-8-en-11-yl]carbamate —— C36H39N3O7
benzyl N-[6-[2-[3-(hydroxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-5,12-dioxo-3-phenyl-1-oxa-4-azacyclododec-8-en-11-yl]carbamate
—— 3,11-dibenzyl-6-[2-[3-(hydroxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-1-oxa-4-azacyclododec-8-ene-5,12-dione —— C36H40N2O5
3,11-dibenzyl-6-[2-[3-(hydroxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-1-oxa-4-azacyclododec-8-ene-5,12-dione
—— 6-[2-[3-(hydroxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-2-phenyl-1-oxa-4-azacyclododec-8-ene-5,12-dione —— C28H32N2O5
6-[2-[3-(hydroxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-2-phenyl-1-oxa-4-azacyclododec-8-ene-5,12-dione
—— N-benzyl-2-(3,13-dibenzyl-5,14-dioxo-1-oxa-4-azacyclotetradec-8-en-6-yl)-N-(2-hydroxyethyl)acetamide —— C37H44N2O5
N-benzyl-2-(3,13-dibenzyl-5,14-dioxo-1-oxa-4-azacyclotetradec-8-en-6-yl)-N-(2-hydroxyethyl)acetamide
—— 2-(11-benzyl-5,12-dioxo-1-oxa-4-azacyclododec-8-en-6-yl)-N-[1-hydroxy-3-(4-phenylmethoxyphenyl)propan-2-yl]acetamide —— C35H40N2O6
2-(11-benzyl-5,12-dioxo-1-oxa-4-azacyclododec-8-en-6-yl)-N-[1-hydroxy-3-(4-phenylmethoxyphenyl)propan-2-yl]acetamide
—— 2-(11-benzyl-3-tert-butyl-5,12-dioxo-1-oxa-4-azacyclododec-8-en-6-yl)-N-[2-(2-hydroxyethoxy)ethyl]acetamide —— C27H40N2O6
2-(11-benzyl-3-tert-butyl-5,12-dioxo-1-oxa-4-azacyclododec-8-en-6-yl)-N-[2-(2-hydroxyethoxy)ethyl]acetamide
—— N-(1-hydroxy-3-phenylpropan-2-yl)-2-(2-methyl-5,14-dioxo-1-oxa-4-azacyclotetradec-8-en-6-yl)acetamide —— C24H34N2O5
N-(1-hydroxy-3-phenylpropan-2-yl)-2-(2-methyl-5,14-dioxo-1-oxa-4-azacyclotetradec-8-en-6-yl)acetamide
—— 2-(13-benzyl-3,3-dimethyl-5,14-dioxo-1-oxa-4-azacyclotetradec-8-en-6-yl)-N-[1-hydroxy-3-(4-phenylmethoxyphenyl)propan-2-yl]acetamide —— C39H48N2O6
2-(13-benzyl-3,3-dimethyl-5,14-dioxo-1-oxa-4-azacyclotetradec-8-en-6-yl)-N-[1-hydroxy-3-(4-phenylmethoxyphenyl)propan-2-yl]acetamide
—— N-benzyl-2-[3-(cyclohexylmethyl)-5,14-dioxo-1-oxa-4-azacyclotetradec-8-en-6-yl]-N-(2-hydroxyethyl)acetamide —— C30H44N2O5
N-benzyl-2-[3-(cyclohexylmethyl)-5,14-dioxo-1-oxa-4-azacyclotetradec-8-en-6-yl]-N-(2-hydroxyethyl)acetamide
—— 11-Benzyl-6-[2-[2-(hydroxymethyl)pyrrolidin-1-yl]-2-oxoethyl]-2-phenyl-1-oxa-4-azacyclododec-8-ene-5,12-dione —— C30H36N2O5
11-Benzyl-6-[2-[2-(hydroxymethyl)pyrrolidin-1-yl]-2-oxoethyl]-2-phenyl-1-oxa-4-azacyclododec-8-ene-5,12-dione
—— benzyl N-[6-[2-[(1-hydroxy-3-phenylpropan-2-yl)amino]-2-oxoethyl]-5,12-dioxo-3-[4-(phenylmethoxycarbonylamino)butyl]-1-oxa-4-azacyclododec-8-en-11-yl]carbamate —— C41H50N4O9
benzyl N-[6-[2-[(1-hydroxy-3-phenylpropan-2-yl)amino]-2-oxoethyl]-5,12-dioxo-3-[4-(phenylmethoxycarbonylamino)butyl]-1-oxa-4-azacyclododec-8-en-11-yl]carbamate
—— N-benzyl-N-(2-hydroxyethyl)-2-[3-(1H-indol-3-ylmethyl)-5,13-dioxo-1-oxa-4-azacyclotridec-8-en-6-yl]acetamide —— C31H37N3O5
N-benzyl-N-(2-hydroxyethyl)-2-[3-(1H-indol-3-ylmethyl)-5,13-dioxo-1-oxa-4-azacyclotridec-8-en-6-yl]acetamide
—— 6-[2-[3-(hydroxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-3-methyl-1-oxa-4-azacyclotetradec-8-ene-5,14-dione —— C25H34N2O5
6-[2-[3-(hydroxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-3-methyl-1-oxa-4-azacyclotetradec-8-ene-5,14-dione
—— 2-(5,13-dioxo-3-propan-2-yl-1-oxa-4-azacyclotridec-8-en-6-yl)-N-[1-(hydroxymethyl)cyclopentyl]acetamide —— C22H36N2O5
2-(5,13-dioxo-3-propan-2-yl-1-oxa-4-azacyclotridec-8-en-6-yl)-N-[1-(hydroxymethyl)cyclopentyl]acetamide
—— 2-(2,11-dioxo-12-oxa-1-azabicyclo[12.3.0]heptadec-5-en-3-yl)-N-[1-(hydroxymethyl)cyclopentyl]acetamide —— C23H36N2O5
2-(2,11-dioxo-12-oxa-1-azabicyclo[12.3.0]heptadec-5-en-3-yl)-N-[1-(hydroxymethyl)cyclopentyl]acetamide
—— 11-benzyl-6-[2-[2-(hydroxymethyl)pyrrolidin-1-yl]-2-oxoethyl]-3-(1H-indol-3-ylmethyl)-1-oxa-4-azacyclododec-8-ene-5,12-dione —— C33H39N3O5
11-benzyl-6-[2-[2-(hydroxymethyl)pyrrolidin-1-yl]-2-oxoethyl]-3-(1H-indol-3-ylmethyl)-1-oxa-4-azacyclododec-8-ene-5,12-dione
—— 3-[2-[2-(Hydroxymethyl)pyrrolidin-1-yl]-2-oxoethyl]-12-oxa-1-azabicyclo[12.3.0]heptadec-5-ene-2,11-dione —— C22H34N2O5
3-[2-[2-(Hydroxymethyl)pyrrolidin-1-yl]-2-oxoethyl]-12-oxa-1-azabicyclo[12.3.0]heptadec-5-ene-2,11-dione
—— 2-(13-benzyl-3,3-dimethyl-5,14-dioxo-1-oxa-4-azacyclotetradec-8-en-6-yl)-N-[1-(hydroxymethyl)cyclopentyl]acetamide —— C29H42N2O5
2-(13-benzyl-3,3-dimethyl-5,14-dioxo-1-oxa-4-azacyclotetradec-8-en-6-yl)-N-[1-(hydroxymethyl)cyclopentyl]acetamide
—— 2-(3-tert-butyl-5,13-dioxo-1-oxa-4-azacyclotridec-8-en-6-yl)-N-[1-(hydroxymethyl)cyclopentyl]acetamide —— C23H38N2O5
2-(3-tert-butyl-5,13-dioxo-1-oxa-4-azacyclotridec-8-en-6-yl)-N-[1-(hydroxymethyl)cyclopentyl]acetamide
—— N-benzyl-N-(2-hydroxyethyl)-2-(3-methyl-5,12-dioxo-1-oxa-4-azacyclododec-8-en-6-yl)acetamide —— C22H30N2O5
N-benzyl-N-(2-hydroxyethyl)-2-(3-methyl-5,12-dioxo-1-oxa-4-azacyclododec-8-en-6-yl)acetamide
—— 2-(12-benzyl-2-methyl-5,13-dioxo-1-oxa-4-azacyclotridec-8-en-6-yl)-N-(1-hydroxypropan-2-yl)acetamide —— C24H34N2O5
2-(12-benzyl-2-methyl-5,13-dioxo-1-oxa-4-azacyclotridec-8-en-6-yl)-N-(1-hydroxypropan-2-yl)acetamide
—— 2-(11-benzyl-3-methyl-5,12-dioxo-1-oxa-4-azacyclododec-8-en-6-yl)-N-[1-(hydroxymethyl)cyclopentyl]acetamide —— C26H36N2O5
2-(11-benzyl-3-methyl-5,12-dioxo-1-oxa-4-azacyclododec-8-en-6-yl)-N-[1-(hydroxymethyl)cyclopentyl]acetamide
—— benzyl N-[6-[2-[2-(hydroxymethyl)pyrrolidin-1-yl]-2-oxoethyl]-5,12-dioxo-3-[(4-phenylmethoxyphenyl)methyl]-1-oxa-4-azacyclododec-8-en-11-yl]carbamate —— C39H45N3O8
benzyl N-[6-[2-[2-(hydroxymethyl)pyrrolidin-1-yl]-2-oxoethyl]-5,12-dioxo-3-[(4-phenylmethoxyphenyl)methyl]-1-oxa-4-azacyclododec-8-en-11-yl]carbamate
—— 6-[2-[3-(hydroxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-1-oxa-4-azacyclotridec-8-ene-5,13-dione —— C23H30N2O5
6-[2-[3-(hydroxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-1-oxa-4-azacyclotridec-8-ene-5,13-dione
—— 2-(5,14-dioxo-1-oxa-4-azacyclotetradec-8-en-6-yl)-N-[1-(hydroxymethyl)cyclopentyl]acetamide —— C20H32N2O5
2-(5,14-dioxo-1-oxa-4-azacyclotetradec-8-en-6-yl)-N-[1-(hydroxymethyl)cyclopentyl]acetamide
—— N-benzyl-2-[3-(benzylsulfanylmethyl)-5,12-dioxo-1-oxa-4-azacyclododec-8-en-6-yl]-N-(2-hydroxyethyl)acetamide —— C29H36N2O5S
N-benzyl-2-[3-(benzylsulfanylmethyl)-5,12-dioxo-1-oxa-4-azacyclododec-8-en-6-yl]-N-(2-hydroxyethyl)acetamide
—— N-benzyl-2-(12-benzyl-2-methyl-5,13-dioxo-1-oxa-4-azacyclotridec-8-en-6-yl)-N-(2-hydroxyethyl)acetamide —— C30H38N2O5
N-benzyl-2-(12-benzyl-2-methyl-5,13-dioxo-1-oxa-4-azacyclotridec-8-en-6-yl)-N-(2-hydroxyethyl)acetamide
—— benzyl N-[4-[6-[2-[2-(2-hydroxyethoxy)ethylamino]-2-oxoethyl]-5,14-dioxo-1-oxa-4-azacyclotetradec-8-en-3-yl]butyl]carbamate —— C30H45N3O8
benzyl N-[4-[6-[2-[2-(2-hydroxyethoxy)ethylamino]-2-oxoethyl]-5,14-dioxo-1-oxa-4-azacyclotetradec-8-en-3-yl]butyl]carbamate
—— 6-[2-[[1-(hydroxymethyl)cyclopentyl]amino]-2-oxoethyl]-N-naphthalen-2-yl-5,12-dioxo-1-oxa-4-azacyclododec-8-ene-3-carboxamide —— C29H35N3O6
6-[2-[[1-(hydroxymethyl)cyclopentyl]amino]-2-oxoethyl]-N-naphthalen-2-yl-5,12-dioxo-1-oxa-4-azacyclododec-8-ene-3-carboxamide
—— Benzyl 6-[2-[benzyl(2-hydroxyethyl)amino]-2-oxoethyl]-5,12-dioxo-11-(phenylmethoxycarbonylamino)-1-oxa-4-azacyclododec-8-ene-3-carboxylate —— C37H41N3O9
Benzyl 6-[2-[benzyl(2-hydroxyethyl)amino]-2-oxoethyl]-5,12-dioxo-11-(phenylmethoxycarbonylamino)-1-oxa-4-azacyclododec-8-ene-3-carboxylate
—— benzyl N-[6-[2-[benzyl(2-hydroxyethyl)amino]-2-oxoethyl]-2-methyl-5,12-dioxo-1-oxa-4-azacyclododec-8-en-11-yl]carbamate —— C30H37N3O7
benzyl N-[6-[2-[benzyl(2-hydroxyethyl)amino]-2-oxoethyl]-2-methyl-5,12-dioxo-1-oxa-4-azacyclododec-8-en-11-yl]carbamate
—— 12-benzyl-6-[2-[3-(hydroxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-3-(1H-indol-3-ylmethyl)-1-oxa-4-azacyclotridec-8-ene-5,13-dione —— C39H43N3O5
12-benzyl-6-[2-[3-(hydroxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-3-(1H-indol-3-ylmethyl)-1-oxa-4-azacyclotridec-8-ene-5,13-dione
—— N-[1-(hydroxymethyl)cyclopentyl]-2-(3-methyl-5,12-dioxo-1-oxa-4-azacyclododec-8-en-6-yl)acetamide —— C19H30N2O5
N-[1-(hydroxymethyl)cyclopentyl]-2-(3-methyl-5,12-dioxo-1-oxa-4-azacyclododec-8-en-6-yl)acetamide
—— 2-(3-benzyl-5,14-dioxo-1-oxa-4-azacyclotetradec-8-en-6-yl)-N-[1-hydroxy-3-(4-phenylmethoxyphenyl)propan-2-yl]acetamide —— C37H44N2O6
2-(3-benzyl-5,14-dioxo-1-oxa-4-azacyclotetradec-8-en-6-yl)-N-[1-hydroxy-3-(4-phenylmethoxyphenyl)propan-2-yl]acetamide
—— 2-(8-benzyl-2,9-dioxo-10-oxa-1-azabicyclo[10.3.0]pentadec-5-en-3-yl)-N-(1-hydroxypropan-2-yl)acetamide —— C25H34N2O5
2-(8-benzyl-2,9-dioxo-10-oxa-1-azabicyclo[10.3.0]pentadec-5-en-3-yl)-N-(1-hydroxypropan-2-yl)acetamide
—— benzyl N-[4-[11-benzyl-6-[2-[benzyl(2-hydroxyethyl)amino]-2-oxoethyl]-5,12-dioxo-1-oxa-4-azacyclododec-8-en-3-yl]butyl]carbamate —— C40H49N3O7
benzyl N-[4-[11-benzyl-6-[2-[benzyl(2-hydroxyethyl)amino]-2-oxoethyl]-5,12-dioxo-1-oxa-4-azacyclododec-8-en-3-yl]butyl]carbamate
—— benzyl N-[6-[2-[3-(hydroxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-2-methyl-5,12-dioxo-1-oxa-4-azacyclododec-8-en-11-yl]carbamate —— C31H37N3O7
benzyl N-[6-[2-[3-(hydroxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-2-methyl-5,12-dioxo-1-oxa-4-azacyclododec-8-en-11-yl]carbamate
—— 2-[11-benzyl-5,12-dioxo-3-(phenylmethoxymethyl)-1-oxa-4-azacyclododec-8-en-6-yl]-N-[1-(hydroxymethyl)cyclopentyl]acetamide —— C33H42N2O6
2-[11-benzyl-5,12-dioxo-3-(phenylmethoxymethyl)-1-oxa-4-azacyclododec-8-en-6-yl]-N-[1-(hydroxymethyl)cyclopentyl]acetamide
—— 6-[2-[2-(Hydroxymethyl)pyrrolidin-1-yl]-2-oxoethyl]-3,3-dimethyl-1-oxa-4-azacyclododec-8-ene-5,12-dione —— C19H30N2O5
6-[2-[2-(Hydroxymethyl)pyrrolidin-1-yl]-2-oxoethyl]-3,3-dimethyl-1-oxa-4-azacyclododec-8-ene-5,12-dione
—— 2-(13-benzyl-3-methyl-5,14-dioxo-1-oxa-4-azacyclotetradec-8-en-6-yl)-N-(1-hydroxy-3-phenylpropan-2-yl)acetamide —— C31H40N2O5
2-(13-benzyl-3-methyl-5,14-dioxo-1-oxa-4-azacyclotetradec-8-en-6-yl)-N-(1-hydroxy-3-phenylpropan-2-yl)acetamide
—— 2-[5,13-dioxo-3-[(4-phenylmethoxyphenyl)methyl]-1-oxa-4-azacyclotridec-8-en-6-yl]-N-[1-(hydroxymethyl)cyclopentyl]acetamide —— C33H42N2O6
2-[5,13-dioxo-3-[(4-phenylmethoxyphenyl)methyl]-1-oxa-4-azacyclotridec-8-en-6-yl]-N-[1-(hydroxymethyl)cyclopentyl]acetamide
—— benzyl N-[6-[2-(1-hydroxypropan-2-ylamino)-2-oxoethyl]-3-methyl-5,12-dioxo-1-oxa-4-azacyclododec-8-en-11-yl]carbamate —— C24H33N3O7
benzyl N-[6-[2-(1-hydroxypropan-2-ylamino)-2-oxoethyl]-3-methyl-5,12-dioxo-1-oxa-4-azacyclododec-8-en-11-yl]carbamate
—— 3-[2-[3-(hydroxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-12-oxa-1-azabicyclo[12.3.0]heptadec-5-ene-2,11-dione —— C27H36N2O5
3-[2-[3-(hydroxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-12-oxa-1-azabicyclo[12.3.0]heptadec-5-ene-2,11-dione
—— 2-[12-benzyl-3-(cyclohexylmethyl)-5,13-dioxo-1-oxa-4-azacyclotridec-8-en-6-yl]-N-(1-hydroxy-3-phenylpropan-2-yl)acetamide —— C36H48N2O5
2-[12-benzyl-3-(cyclohexylmethyl)-5,13-dioxo-1-oxa-4-azacyclotridec-8-en-6-yl]-N-(1-hydroxy-3-phenylpropan-2-yl)acetamide
—— 2-(13-benzyl-3-tert-butyl-5,14-dioxo-1-oxa-4-azacyclotetradec-8-en-6-yl)-N-[1-hydroxy-3-(4-phenylmethoxyphenyl)propan-2-yl]acetamide —— C41H52N2O6
2-(13-benzyl-3-tert-butyl-5,14-dioxo-1-oxa-4-azacyclotetradec-8-en-6-yl)-N-[1-hydroxy-3-(4-phenylmethoxyphenyl)propan-2-yl]acetamide
—— 2-[12-benzyl-3-(methoxymethyl)-5,13-dioxo-2-phenyl-1-oxa-4-azacyclotridec-8-en-6-yl]-N-[2-(2-hydroxyethoxy)ethyl]acetamide —— C32H42N2O7
2-[12-benzyl-3-(methoxymethyl)-5,13-dioxo-2-phenyl-1-oxa-4-azacyclotridec-8-en-6-yl]-N-[2-(2-hydroxyethoxy)ethyl]acetamide
—— 6-[2-[3-(hydroxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-1-oxa-4-azacyclododec-8-ene-5,12-dione —— C22H28N2O5
6-[2-[3-(hydroxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-1-oxa-4-azacyclododec-8-ene-5,12-dione
—— 12-benzyl-6-[2-[3-(hydroxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-1-oxa-4-azacyclotridec-8-ene-5,13-dione —— C30H36N2O5
12-benzyl-6-[2-[3-(hydroxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-1-oxa-4-azacyclotridec-8-ene-5,13-dione