(2R,4S,5R,6R)-4-Acetoxy-6-{(S)-acetoxy-[(2R,6S,8R,9R,10S)-10-acetoxy-9-acetylamino-5-oxo-8-((1S,2R)-1,2,3-triacetoxy-propyl)-1,4,7-trioxa-spiro[5.5]undec-2-yl]-methyl}-5-acetylamino-2-allyloxy-tetrahydro-pyran-2-carboxylic acid methyl ester | 193360-99-5

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (2R,4S,5R,6R)-4-Acetoxy-6-{(S)-acetoxy-[(2R,6S,8R,9R,10S)-10-acetoxy-9-acetylamino-5-oxo-8-((1S,2R)-1,2,3-triacetoxy-propyl)-1,4,7-trioxa-spiro[5.5]undec-2-yl]-methyl}-5-acetylamino-2-allyloxy-tetrahydro-pyran-2-carboxylic acid methyl ester
• CAS: 193360-99-5
• 化学式: C₃₈H₅₂N₂O₂₂
• 分子量: 888.831
• InChiKey: FEAPRPYYMPEVCR-HNDXNVSYSA-N

反应信息

• 作为反应物：
  描述：

  (2R,4S,5R,6R)-4-Acetoxy-6-{(S)-acetoxy-[(2R,6S,8R,9R,10S)-10-acetoxy-9-acetylamino-5-oxo-8-((1S,2R)-1,2,3-triacetoxy-propyl)-1,4,7-trioxa-spiro[5.5]undec-2-yl]-methyl}-5-acetylamino-2-allyloxy-tetrahydro-pyran-2-carboxylic acid methyl ester 在 sodium hydroxide 、 sodium methylate 、 sodium cyanoborohydride 、 臭氧 作用下， 以 甲醇 为溶剂， 反应 2.0h， 生成
  参考文献：
  名称：

  Design and Synthesis of b-Series Ganglioside Mimetics

  摘要：

  Artificial glycolipids composed from phosphatidyl-ethanolamine and one or two sets of sialylα(2-8)sialoside were designed and prepared as mimetics of b-series gangliosides, GD3 and GQlb, which have respectively cholinergic differentiation potency in murine neuroblastoma cells and neutritogenic effect in human neuroblastoma cell line.

  DOI：

  10.1055/s-1997-3259
• 作为产物：
  描述：

  烯丙醇 、 (2R,4S,5R,6R)-4-Acetoxy-6-{(S)-acetoxy-[(2R,6S,8R,9R,10S)-10-acetoxy-9-acetylamino-5-oxo-8-((1S,2R)-1,2,3-triacetoxy-propyl)-1,4,7-trioxa-spiro[5.5]undec-2-yl]-methyl}-5-acetylamino-2-chloro-tetrahydro-pyran-2-carboxylic acid methyl ester 在 silver salicylate 作用下， 生成 (2R,4S,5R,6R)-4-Acetoxy-6-{(S)-acetoxy-[(2R,6S,8R,9R,10S)-10-acetoxy-9-acetylamino-5-oxo-8-((1S,2R)-1,2,3-triacetoxy-propyl)-1,4,7-trioxa-spiro[5.5]undec-2-yl]-methyl}-5-acetylamino-2-allyloxy-tetrahydro-pyran-2-carboxylic acid methyl ester
  参考文献：
  名称：

  Design and Synthesis of b-Series Ganglioside Mimetics

  摘要：

  Artificial glycolipids composed from phosphatidyl-ethanolamine and one or two sets of sialylα(2-8)sialoside were designed and prepared as mimetics of b-series gangliosides, GD3 and GQlb, which have respectively cholinergic differentiation potency in murine neuroblastoma cells and neutritogenic effect in human neuroblastoma cell line.

  DOI：

  10.1055/s-1997-3259