| 1257092-56-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 芘
• CAS: 1257092-56-0
• 化学式: C₂₃H₁₈Si
• 分子量: 322.481
• InChiKey: TUHUAHDGDKEEDO-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  、 苄基叠氮 在 水 、 potassium carbonate 、 copper(ll) sulfate pentahydrate 、 维生素 C 作用下， 以 四氢呋喃 、 甲醇 、 水 、 N,N-二甲基甲酰胺 为溶剂， 以62%的产率得到1-Benzyl-4-(2-pyren-2-ylethynyl)triazole
  参考文献：
  名称：

  Reactions of Terminal Polyynes with Benzyl Azide

  摘要：

  Terminal di-, tri-, tetra-, and pentaynes substituted with a variety of functional groups react with benzyl azide in the presence of CuSO4 center dot 5H(2)O and ascorbic acid to give derivatives of 4-ethynyl-, 4-butadiynyl-, 4-hexatriynyl-, and 4-octatetraynyl-,2,3-triazoles in moderate to good yields. These reactions appear to proceed regioselectively, and functionalization occurs exclusively at the terminal alkyne moiety. As well, no evidence of multiple azide additions to the polyyne framework is observed. X-ray crystallographic analysis of nine derivatives is used to document the regioselectivity of the reaction as well as outline structural characteristics of the 1,2,3-triazole products.

  DOI：

  10.1021/jo101870y