| 1172601-94-3

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磺酸及其衍生物
• CAS: 1172601-94-3
• 化学式: C₁₂H₁₈O₇S
• 分子量: 306.337
• InChiKey: GDQBSLQOBVMNLY-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  在 sodium carbonate 、 sodium iodide 作用下， 以 丙酮 为溶剂， 反应 1.0h， 以78%的产率得到2-((E)-iodomethylene)-1,1-bis(methoxycarbonyl)cyclohexane
  参考文献：
  名称：

  An X⁻ (X = I, Br)-Triggered Ring-Opening Cyclization of Cyclopropenyl-Substituted Alkyl Halides or Mesylates: An Efficient and Highly Regio- and Stereoselective Approach to (E)-Haloalkylidene 4−7-Membered Cyclic Compounds

  摘要：

  Polyfunctionalized (E)-haloalkylidene cyclic products were efficiently synthesized in moderate to excellent yields via a regio- and stereoselective X- (X = I or Br)-triggered ring-opening intramolecular trapping of cyclopropenes 1. The reaction can be used for construction of 4-7-membered products. The E-stereoselectivity of the exo-C=C bond is very high. The carbon-halogen bond in the exo-C=C bond may further be elaborated to prepare differently substituted cyclic products with a stereodefined C=C bond.

  DOI：

  10.1021/jo900389m