| 1316280-75-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• CAS: 1316280-75-7
• 化学式: C₁₆H₉F₂NO₂
• 分子量: 285.25
• InChiKey: BDRZBDSMPDIIQY-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  在 双氧水 、 十六烷基三甲基溴化铵 、 sodium hydroxide 作用下， 以 水 为溶剂， 反应 0.2h， 以92%的产率得到
  参考文献：
  名称：

  Facile stereoslective synthesis of spiro[indole-oxiranes] by combination of phase transfer catalyst and ultrasound irradiation and their bioassay

  摘要：

  An alternative and environmentally benign pathway for diastereoslective synthesis of fluorinated spiro[indole-3,2'-oxirane]-3'-benzoyl-2(1H)-ones (2a-g) is reported. The spiro[indole-3.2'-oxiranes] derivatives were obtained in 90-97% yield exclusively via the epoxidation of 3-aroylmethylene indole-2-ones with 30% aqueous hydrogen peroxide using cetyltrimethyl ammonium bromide as a phase transfer catalyst under ultrasound irradiation. The lead compounds have been tested for their antimicrobial activity and antioxidant properties. (C) 2010 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.ultsonch.2010.12.010