| 1100884-56-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• CAS: 1100884-56-7
• 化学式: C₄₁H₇₄N₃O₇*Cl
• 分子量: 756.507
• InChiKey: CXVHBDUILOFPPQ-CBHJHVDXSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.36
• 重原子数：
  52.0
• 可旋转键数：
  30.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.85
• 拓扑面积：
  137.35
• 氢给体数：
  5.0
• 氢受体数：
  7.0

反应信息

• 作为反应物：
  描述：

  在 platinum on activated charcoal 、 氢气 作用下， 以 甲醇 为溶剂， 反应 48.0h， 以90%的产率得到
  参考文献：
  名称：

  Synthesis of unsymmetrical saturated or diacetylenic cationic bolaamphiphiles

  摘要：

  This work presents the synthesis of novel unsymmetrical bolaamphiphiles bearing a sugar residue and a cationic glycine betaine moiety connected to both ends of a C-22 or C-32 oligomethylene bridging chain possessing or not a diacetylenic unit. Preliminary transmission electron microscopy (TEM) studies revealed the polymorphism of these bola lipids with regard to their self-assembled morphologies in water depending on the presence or not of the diacetylenic functionality and on alkyl chain length. (C) 2008 Elsevier Ltd, All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.10.073
• 作为产物：
  描述：

  3-betainylthiazolidine-2-thione chloride 、 C₃₆H₆₄N₂O₆ 以 N,N-二甲基甲酰胺 为溶剂， 反应 3.0h， 以60%的产率得到
  参考文献：
  名称：

  Synthesis of unsymmetrical saturated or diacetylenic cationic bolaamphiphiles

  摘要：

  This work presents the synthesis of novel unsymmetrical bolaamphiphiles bearing a sugar residue and a cationic glycine betaine moiety connected to both ends of a C-22 or C-32 oligomethylene bridging chain possessing or not a diacetylenic unit. Preliminary transmission electron microscopy (TEM) studies revealed the polymorphism of these bola lipids with regard to their self-assembled morphologies in water depending on the presence or not of the diacetylenic functionality and on alkyl chain length. (C) 2008 Elsevier Ltd, All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.10.073