| 129199-15-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• CAS: 129199-15-1
• 化学式: C₇₇H₆₇BrO₂₄
• 分子量: 1456.27
• InChiKey: IIAQVYIPUDXBOD-UXGLPCBHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  13.3
• 重原子数：
  102
• 可旋转键数：
  35
• 环数：
  11.0
• sp3杂化的碳原子比例：
  0.26
• 拓扑面积：
  292
• 氢给体数：
  0
• 氢受体数：
  24

反应信息

• 作为反应物：
  描述：

  、 乙酸酐 、 甲醇 、 sodium methylate 、 吡啶 生成 Acetic acid (2R,3R,4S,5S,6R)-3,5-diacetoxy-2-((2R,3R,5R,6S)-3,5-diacetoxy-6-methoxy-tetrahydro-pyran-2-ylmethoxy)-6-((2R,3R,4S,5S,6R)-3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-yloxymethyl)-tetrahydro-pyran-4-yl ester
  参考文献：
  名称：

  KOVAC, PAVOL;EDGAR, KEVIN J., CARBOHYDR. RES., 201,(1990) N, C. 79-93

  摘要：

  DOI：
• 作为产物：
  描述：

  methyl 2,4-di-O-benzoyl-3-deoxy-β-D-xylo-hexopyranoside 、 O-(2,3,4-tri-O-benzoyl-6-O-bromoacetyl-β-D-galactopyranosyl)-(1-6)-2,3,4-tri-O-benzoyl-α-D-galactopyranosyl chloride 在 2,4,6-三甲基吡啶 、 silver trifluoromethanesulfonate 作用下， 以 二氯甲烷 为溶剂， 反应 0.25h， 生成 、 methyl O-(2,3,4-tri-O-benzoyl-6-O-bromoacetyl-β-D-galactopyranosyl)-(1->6)-O-(2,3,4-tri-O-benzoyl-β-D-galactopyranosyl)-(1->6)-2,4-di-O-benzoyl-3-deoxy-β-D-xylo-hexopyranoside
  参考文献：
  名称：

  Synthesis of a series of methyl β-glycosides of (1→6)-β-d-galacto-oligosaccharides having one residue deoxygenated at position 3

  摘要：

  Methyl beta-glycosides of beta-(1----6)-linked D-galactobioses (13 and 16) and -galactotrioses (21, 24, and 26) containing a 3-deoxy-beta-D-xylo-hexopyranosyl moiety either as one of the end units or the internal unit have been synthesized. The extension of the oligosaccharide chain was achieved, inter alia, by the use of two newly synthesized glycosyl donors derived from 3-deoxy-D-xylo-hexopyranose, namely, 2,4,6-tri-O-benzoyl-3-deoxy-a-D-xylo-hexopyranosyl chloride (8) and 2,4-di-O-benzoyl-6-O-bromoacetyl-3-deoxy-a-D-xylo-hexopyranosyl chloride (10). Glycosylation reactions were mediated by silver triflate under base-deficient conditions.

  DOI：

  10.1016/0008-6215(90)84226-k