N-{[3-(2H-Benzotriazol-2-yl)-2-hydroxy-5-(2,4,4-trimethylpentan-2-yl)phenyl]methyl}-2-methylprop-2-enamide | 107479-06-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: N-{[3-(2H-Benzotriazol-2-yl)-2-hydroxy-5-(2,4,4-trimethylpentan-2-yl)phenyl]methyl}-2-methylprop-2-enamide
• 英文别名: N-[[3-(benzotriazol-2-yl)-2-hydroxy-5-(2,4,4-trimethylpentan-2-yl)phenyl]methyl]-2-methylprop-2-enamide
• CAS: 107479-06-1
• 化学式: C₂₅H₃₂N₄O₂
• 分子量: 420.5
• InChiKey: PUKBPIIUNNWYDU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7
• 重原子数：
  31
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  80
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  奥克三唑 、 N-(羟甲基)-2-甲基-2-丙烯酰胺 生成 N-{[3-(2H-Benzotriazol-2-yl)-2-hydroxy-5-(2,4,4-trimethylpentan-2-yl)phenyl]methyl}-2-methylprop-2-enamide
  参考文献：
  名称：

  摘要：

  DOI：

文献信息

• Ocular devices manufactured with free radical-polymerizable latent ultra-violet absorbers
  申请人：JOHNSON & JOHNSON VISION PRODUCTS, INC.

  公开号：EP1584952A1

  公开（公告）日：2005-10-12

  The invention provides compositions for forming ocular devices which compositions contain latent UV absorbers. The compositions of the invention may be used to conveniently and efficiently produce ocular devices through UV initiated, free radical polymerization.

  该发明提供了含有潜在紫外线吸收剂的形成眼部装置的组合物。该发明的组合物可用于通过紫外线引发的自由基聚合方便高效地生产眼部装置。
• PREPOLYMERS SUITABLE FOR MAKING ULTRA-VIOLET ABSORBING CONTACT LENSES
  申请人：Domschke Angelika Maria

  公开号：US20110063567A1

  公开（公告）日：2011-03-17

  The invention provides a class of actinically-crosslinkable silicone-containing prepolymers which comprise (1) ethylenically-unsaturated groups and (2) UV-absorbing polymeric units, latent UV-absorbing polymeric units, and/or dual photo-functional polymeric units. The prepolymer of the invention can be used to prepare silicone hydrogel contact lenses capable of absorbing UV/visible radiation. The present invention is also related to silicone hydrogel contact lenses made from a prepolymer of the invention and methods for making the contact lenses in a cost-effective way and with high consistency and high fidelity to the original lens design.

  本发明提供一类光致交联硅含量预聚物，其包括（1）乙烯基-不饱和基团和（2）紫外线吸收聚合物单元、潜在紫外线吸收聚合物单元和/或双重光功能聚合物单元。本发明的预聚物可用于制备能够吸收紫外线/可见光辐射的硅水凝胶隐形眼镜。本发明还涉及使用本发明预聚物制造硅水凝胶隐形眼镜的方法，以成本效益高、一致性高和对原始镜片设计的高度忠实。
• SOFT ACRYLIC MATERIALS WITH HIGH REFRACTIVE INDEX AND MINIMIZED GLISTENING
  申请人：NOVARTIS AG

  公开号：US20150151022A1

  公开（公告）日：2015-06-04

  High refractive index acrylic device materials with reduced glistenings are disclosed. The device materials are particularly suitable for use as ophthalmic or otorhhinolaryngological device materials and comprises a poly(phenyl ether)-containing monomer and/or a poly(phenyl ether)-containing cross-linking agent.

  公开了具有减少闪光的高折射率丙烯酸酯器件材料。该器件材料特别适用于作为眼科或耳鼻喉科器件材料，并包括含有聚苯醚单体和/或聚苯醚交联剂的材料。
• WET-PACK INTRAOCULAR LENS MATERIALS WITH HIGH REFRACTIVE INDEX
  申请人：Novartis AG

  公开号：US20160235886A1

  公开（公告）日：2016-08-18

  Intraocular lens materials are disclosed. They are soft and very deformable and have a high refractive index, and a high glistening resistance in fully hydrated state. They are particularly suitable for making wet-packed intraocular lenses (IOLs) which can be delivered through sub 2.0 mm incisions.

  本文披露了一种人工晶体材料。该材料柔软、易变形，具有高折射率和高抗水晶体闪光的特点。它特别适用于制作湿式包装的人工晶体（IOL），可通过小于2.0毫米的切口进行输送。
• Corneal implants
  申请人：SHIUEY, Yichieh

  公开号：EP2404573A1

  公开（公告）日：2012-01-11

  A corneal implant (50,60) comprising a body having a protruding center optic (52,62) at least partially surrounded by a rim (54,64), said body composed of a material having a tensile strength in the range from 0.1 MPa to 4 MPa and a modulus in the range from 0.1 MPa to 5 MPa, wherein center optic (52) can extend anteriorly from the rim (54) or the center optic (62) can additionally extend posteriorly from the implant.

  一种角膜植入物（50,60），包括一个主体，该主体具有一个突出的中心光学元件（52,62），至少部分被一个边缘（54,64）包围，所述主体由一种材料组成，该材料的抗拉强度在 0.1 兆帕到 4 兆帕之间，模量在 0.1 兆帕到 5 兆帕之间，其中中心光学元件（52）可以从边缘（54）向前方延伸，或者中心光学元件（62）还可以从植入物向后方延伸。