Omega-(2-oxo-benzimidazolinyl)-alkanoic acid derivatives, process for producing the same and pharmaceutical compounds containing the same
申请人:A. Nattermann & Cie. GmbH
公开号:EP0051827A1
公开(公告)日:1982-05-19
The present invention refers to new ω-(2-oxo- benzazolinyl)-alkanoic acids as well as salts and esters thereof having the general formula I
process for producing the same and pharmaceutical preparations containing the same.
本发明涉及具有通式 I 的新ω-(2-氧代-苯并唑啉基)-烷酸及其盐和酯。
以及含有这些物质的药物制剂。
N-benzoyl-alpha-anilino alkane carboxylic acids, salts and esters thereof, process for producing the same and pharmaceutical preparations containing the same
申请人:A. Nattermann & Cie. GmbH
公开号:EP0051828A1
公开(公告)日:1982-05-19
The present invention refers to N-Benzoyl-ω-anilinoalkane carboxylic acids, their esters and salts of the general formula
having thrombocyte aggregation inhibiting effectiveness, processes for producing the same and drugs containing the same.
N-substituted omega-(2-oxo-4-imidazolin-1-yl) alcanoic acids, salts and esters thereof, process for producing the same and these active agents containing pharmaceutical compounds
申请人:A. Nattermann & Cie. GmbH
公开号:EP0051829A1
公开(公告)日:1982-05-19
the present invention refers to new N-substituted ω-(2-oxo-4-imidazolin-1-yl) alcanoic acids as well as salts and esters thereof having the general formula I
process for producing the same and these active agents containing pharmaceutical compounds.
本发明是指新的 N-取代ω-(2-氧代-4-咪唑啉-1-基)辛酸及其具有通式 I 的盐和酯,以及这些含有药物活性剂的化合物的生产工艺。
Azido-substituted fatty acid analog enzyme substrates
申请人:WASHINGTON UNIVERSITY
公开号:EP0480901A1
公开(公告)日:1992-04-15
Azido-substituted fatty acid analogs which are useful in the fatty acid acylation of peptides and proteins and as antiviral agents are disclosed having the following chemical structure:
Z - (CH₂)xCOOR
wherein
Z = azido, tetrazolyl or triazolyl
R = H or C₁-C₈ alkyl, and
x = 8-12
or structure (I) as defined above and wherein a methylene group from carbon position 3 to within 2 carbons of Z is replaced with oxygen or sulfur.
已公开的叠氮取代脂肪酸类似物具有以下化学结构,可用于肽和蛋白质的脂肪酸酰化,也可用作抗病毒剂:
Z - (CH₂)xCOOR
其中
Z = 叠氮基、四唑基或三唑基
R = H 或 C₁-C₈ 烷基,以及
x = 8-12
或如上定义的结构(I),其中 Z 的第 3 碳位至 2 碳位内的亚甲基被氧或硫取代。
Process for preparing hydroxycarboxylic acids
申请人:UNILEVER PLC
公开号:EP0711746A1
公开(公告)日:1996-05-15
A new synthesis of ω-hydroxy acids, which employs commercially available starting materials and lowers the cost of production. The process involves coupling a fatty acyl group by enamine chemistry, followed by a ring expansion and selective reduction of ketoacid.