8-(4-Hydroxyphenyl)octansaeure | 24536-03-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 8-(4-Hydroxyphenyl)octansaeure
• 英文别名: 8-(4-hydroxyphenyl)octanoic acid
• CAS: 24536-03-6
• 化学式: C₁₄H₂₀O₃
• 分子量: 236.311
• InChiKey: OFLJZPISIJSAMK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  17
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  57.5
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  8-(4-Hydroxyphenyl)octansaeure 生成 Ethyl 8-(4-hydroxyphenyl)octanoate
  参考文献：
  名称：

  AULTZ D. E.; MCFADDEN A. R., J. MED. CHEM. , 1977, 20, NO 11, 1499-1501

  摘要：

  DOI：
• 作为产物：
  描述：

  8-(4-methoxyphenyl)octanoic acid 、 氢溴酸 、 溶剂黄146 生成 8-(4-Hydroxyphenyl)octansaeure
  参考文献：
  名称：

  AULTZ D. E.; MCFADDEN A. R., J. MED. CHEM. , 1977, 20, NO 11, 1499-1501

  摘要：

  DOI：

文献信息

• [EN] COMPOUNDS CONTAINING MATRIX METALLOPROTEINASE SUBSTRATES AND METHODS OF THEIR USE<br/>[FR] COMPOSES CONTENANT DES SUBSTRATS DE METALLOPROTEINASE MATRICIELLE ET PROCEDES D'UTILISATION ASSOCIES
  申请人：BRISTOL MYERS SQUIBB CO

  公开号：WO2005023314A1

  公开（公告）日：2005-03-17

  Compounds for use in a diagnostic agent for detecting, imaging, and/or monitoring a pathological disorder associated with matrix metalloproteinase activity at a site of interest in a patient are disclosed. Compositions and kits containing the compounds are also disclosed. In addition, methods of detecting, imaging, and/or monitoring the presence of matrix metalloproteinase or a pathological disorder associated with matrix metalloproteinase activity in a patient are disclosed.

  揭示了用于诊断剂的化合物，用于检测、成像和/或监测患者感兴趣部位处与基质金属蛋白酶活性相关的病理紊乱。还揭示了含有这些化合物的组合物和试剂盒。此外，还揭示了检测、成像和/或监测患者体内基质金属蛋白酶或与基质金属蛋白酶活性相关的病理紊乱存在的方法。
• Compounds containing matrix metalloproteinase substrates and methods of their use
  申请人：Harris D. Thomas

  公开号：US20050106100A1

  公开（公告）日：2005-05-19

  Compounds for use in a diagnostic agent for detecting, imaging, and/or monitoring a pathological disorder associated with matrix metalloproteinase activity at a site of interest in a patient are disclosed. Compositions and kits containing the compounds are also disclosed. In addition, methods of detecting, imaging, and/or monitoring the presence of matrix metalloproteinase or a pathological disorder associated with matrix metalloprotainase activity in a patient are disclosed.

  本文介绍了用于诊断检测、成像和/或监测患者体内与基质金属蛋白酶活性相关的病理性疾病的化合物。还公开了含有这些化合物的组合物和试剂盒。此外，还公开了检测、成像和/或监测患者体内基质金属蛋白酶或与基质金属蛋白酶活性相关的病理性疾病存在的方法。
• Carboxy-functionalized polyphenylene ethers and blends containing them
  申请人：——

  公开号：US20010034430A1

  公开（公告）日：2001-10-25

  Carboxy-functionalized polyphenylene ethers containing structural units with a carboxyalkyl group in the 2-position are prepared by redistribution of a polyphenylene ether with a 2-carboxyalkylphenol such as 2-(3-carboxypropyl)phenol (melilotic acid), or by oxidative coupling of a suitable phenol with such a 2-carboxyalkylphenol. The products form compatibilizing copolymers with polymers containing carboxylic acid-reactive functional groups, such as polyesters, polyamides and epoxy resins.

  通过将聚苯醚与 2-羧基烷基酚（如 2-(3-羧丙基)苯酚（美利洛酸））进行再分配，或将合适的苯酚与这种 2-羧基烷基酚进行氧化偶联，可制备出含有 2 位羧基烷基结构单元的羧基官能团聚苯醚。这些产品可与含有羧酸反应官能团的聚合物（如聚酯、聚酰胺和环氧树脂）形成相容共聚物。
• REDISTRIBUTION OF POLYPHENYLENE ETHERS AND POLYPHENYLENE ETHERS WITH NOVEL STRUCTURE
  申请人：GENERAL ELECTRIC COMPANY

  公开号：EP0895519A1

  公开（公告）日：1999-02-10
• CARBOXY-FUNCTIONALIZED POLYPHENYLENE ETHERS AND BLENDS CONTAINING THEM
  申请人：GENERAL ELECTRIC COMPANY

  公开号：EP1086160A1

  公开（公告）日：2001-03-28