sulfaphenazole | 54371-69-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: sulfaphenazole
• 英文别名: 1-Phenyl-3-<4-aminophenylsulfamido>pyrazol；1-Phenyl-3-(4-aminobenzolsulfonylamino)pyrazol；3-(4-Aminobenzolsulfonylamino)-1-phenylpyrazol；4-amino-N-(1-phenyl-1H-pyrazol-3-yl)-benzenesulfonamide；4-amino-N-(1-phenylpyrazol-3-yl)benzenesulfonamide
• CAS: 54371-69-6
• 化学式: C₁₅H₁₄N₄O₂S
• 分子量: 314.368
• InChiKey: CTMRCAADNHCNDZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  22
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  98.4
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  sulfaphenazole 以46%的产率得到
  参考文献：
  名称：

  ROUSHDI I. M.; MIKHAIL A. A., PHARMAZIE, 1977, 32, NO 5, 269-270

  摘要：

  DOI：

文献信息

• Synthesis and GC-Eims Analyses of Optically Pure 3-Hydroxy-2-Azetidinones Having<i>N</i>-Sulfonamide Drugs Side Chain
  作者：Hammed H. A. M. Hassan、Raafat Soliman

  DOI：10.1080/00397910008087410

  日期：2000.7

  A series of new N-sulfonamides of substituted 3-hydroxy-2-azetidinones were prepared by the [2+2] cycloaddition of aldoximes, formed from the condensation of D-(R)-glyceraldehyde acetonide and the potent p-aminophenyl-N-substituted sulfonamides, with benzyloxyacetyl chloride followed by removal of the protecting groups. Obtaining both diastereoisomeric forms of beta-lactams by resorting to kinetic resolution starting from racemic imino analogue is also described. The GC-EIMS, spectroscopic and analytical analyses for some of these derivatives are reported.
• SHANKER, RAVI, CH.;RAO, DEVENDER, A.;BHASKAR, A.;REDDY, MALLA, V.;SATTUR,+, CURR. SCI., INDIA, 1984, 53, N 20, 1069-1071
  作者：SHANKER, RAVI, CH.、RAO, DEVENDER, A.、BHASKAR, A.、REDDY, MALLA, V.、SATTUR,+

  DOI：——

  日期：——