5,6-Dihydroxy-3,7,4'-trimethoxyflavone

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: 5,6-Dihydroxy-3,7,4'-trimethoxyflavone
• 英文别名: 5,6-dihydroxy-3,7-dimethoxy-2-(4-methoxyphenyl)chromen-4-one
• 化学式: C₁₈H₁₆O₇
• 分子量: 344.3
• InChiKey: OIQSGZWRLLAFNQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  25
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  94.4
• 氢给体数：
  2
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  1-(3,6-dihydroxy-2,4-dimethoxy-phenyl)-2-methoxy-ethanone 生成 5,6-Dihydroxy-3,7,4'-trimethoxyflavone
  参考文献：
  名称：

  HORIE, TOKUNARU;KAWAMURA, YASUHIKO;TSUKAYAMA, MASAO;YOSHIZAKI, SHIRO, CHEM. AND PHARM. BULL., 37,(1989) N, C. 1216-1220

  摘要：

  DOI：

文献信息

• Soy containing formulations for the improvement of skin radiance
  申请人：Johnson & Johnson Consumer France SAS

  公开号：EP1543822A1

  公开（公告）日：2005-06-22

  This invention relates to topical formulations containing both feverfew extract and soy extract and the use thereof to increase skin radiance.

  本发明涉及同时含有发热草提取物和大豆提取物的外用制剂，以及使用它们来增加皮肤光泽的方法。
• Gingko containing formulations for the improvement of skin radiance
  申请人：Johnson & Johnson Consumer France SAS

  公开号：EP1543823A1

  公开（公告）日：2005-06-22

  This invention relates to topical formulations containing both feverfew extract and Gingko biloba extract and the use thereof to increase skin radiance.

  本发明涉及同时含有发热草提取物和银杏叶提取物的外用制剂，以及使用这些制剂增加皮肤光泽的方法。
• Compositions containing amines and use thereof
  申请人：JOHNSON & JOHNSON CONSUMER COMPANIES, INC.

  公开号：EP1698325A1

  公开（公告）日：2006-09-06

  The present invention features compositions comprising at least one compound of the formula I or formula II: wherein R1, R2, R3, R4, and R5 independently, are selected from the group consisting of hydrogen, C1-C6 alkyl, C1-C6 hydroxyalkyl, or a cosmetically acceptable salt thereof, and the use thereof.

  本发明的特征是包含至少一种式 I 或式 II 化合物的组合物： 其中 R1、R2、R3、R4 和 R5 分别独立地选自氢、C1-C6 烷基、C1-C6 羟烷基或其美容上可接受的盐组成的组。
• Compositions and methods for mitigating skin irritation
  申请人：Johnson and Johnson Consumer Companies, Inc.

  公开号：EP1762241A1

  公开（公告）日：2007-03-14

  The invention relates to a composition and a method for mitigating redness or inflammation of mammalian skin comprising administering to mammalian skin a composition consisting of an effective amount of alkanolamine, feverfew or soy or mixtures thereof, one or more optional benefit agents and one or more cosmetically acceptable carriers. More particularly, it relates to a composition for mitigating skin irritations such as retinol/retinoid irritation and their applications to mammalian skin.

  本发明涉及一种减轻哺乳动物皮肤发红或发炎的组合物和方法，包括向哺乳动物皮肤施用一种组合物，该组合物由有效量的烷醇胺、发热草或大豆或其混合物、一种或多种可选的益处剂和一种或多种美容上可接受的载体组成。更具体地说，它涉及一种用于减轻皮肤刺激（如视黄醇/维甲酸刺激）的组合物及其在哺乳动物皮肤上的应用。
• Compositions containing an extract of a primula denticulata and use thereof
  申请人：Johnson and Johnson Consumer Companies, Inc.

  公开号：EP1941893A2

  公开（公告）日：2008-07-09

  The present invention features composition comprising an extract of a primula denticulata and the use thereof for treating acne and reducing the appearance of oil or pores on the skin, hair and scalp.

  本发明的特点是含有一种报春花提取物的组合物及其用于治疗痤疮和减少皮肤、头发和头皮上的油脂或毛孔。