2-ethoxyethyl (2Z)-cyano-{3-[(3-methoxypropyl)amino]cyclohex-2-en-1-ylidene}ethanoate | 1419401-77-6

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-ethoxyethyl (2Z)-cyano-{3-[(3-methoxypropyl)amino]cyclohex-2-en-1-ylidene}ethanoate
• 英文别名: 2-Ethoxyethyl 2-cyano-2-[3-(3-methoxypropylamino)cyclohex-2-en-1-ylidene]acetate；2-ethoxyethyl 2-cyano-2-[3-(3-methoxypropylamino)cyclohex-2-en-1-ylidene]acetate
• CAS: 1419401-77-6
• 化学式: C₁₇H₂₆N₂O₄
• 分子量: 322.404
• InChiKey: NPNDSRGIZUPLNP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  23
• 可旋转键数：
  11
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.65
• 拓扑面积：
  80.6
• 氢给体数：
  1
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  氰乙酸乙氧基乙酯 、 3-[(3-methoxypropyl)amino]-2-cyclohexen-1-one 在 1,8-二氮杂双环[5.4.0]十一碳-7-烯 作用下， 以 N,N-二甲基乙酰胺 为溶剂， 生成 2-ethoxyethyl (2Z)-cyano-{3-[(3-methoxypropyl)amino]cyclohex-2-en-1-ylidene}ethanoate
  参考文献：
  名称：

  COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE, AN OILY PHASE AND A C1-C4 MONOALKANOL

  摘要：

  本发明涉及一种化妆品或皮肤科学组合物，包含以下成分：a）至少一种式(1)或(2)的黄绿素化合物；b）至少一种油性相；c）至少一种C1-C4单醇。本发明还涉及一种非治疗性化妆过程，用于护理和/或化妆角蛋白质材料，包括将上述至少一种组合物应用于所述角蛋白质材料的表面。本发明还涉及一种非治疗性化妆过程，用于限制皮肤变黑和/或改善肤色和/或肤色均匀性，包括将上述至少一种组合物应用于皮肤表面。本发明还涉及一种非治疗性化妆过程，用于预防和/或治疗角蛋白质材料的衰老迹象，包括将上述至少一种组合物应用于所述角蛋白质材料的表面。

  公开号：

  US20150335556A1

文献信息

• [EN] MEROCYANINE DERIVATIVES<br/>[FR] DÉRIVÉS DE MÉROCYANINE
  申请人：BASF SE

  公开号：WO2013011480A1

  公开（公告）日：2013-01-24

  Disclosed are compounds of formula (1) and (2) and/or E/E-, E/Z- or Z/Z geometrical isomer forms thereof; wherein R1-R5, R1-R11 and A are defined as in description. The compounds are used as UV absorbers for protecting household products from photolytic and oxidative degradation, as plastic additives, preferably for food and pharmaceutical packaging applications, for preventing photo-degradation of food by incorporation of the compounds of formula (1 ') and/or (2') into transparent food containers, for protection of UV-A sensitive drugs from photo-degradation by incorporation of UV absorber in transparent blister foils or transparent pharmacy containers, as additives for photographic and printing applications, as additives for electronic applications and protecting the ingredients in agriculture applications.

  公开了式（1）和（2）的化合物及其E/E-、E/Z-或Z/Z几何异构体形式；其中R1-R5、R1-R11和A的定义如描述中所述。这些化合物被用作紫外线吸收剂，用于保护家庭产品免受光解和氧化降解的影响，作为塑料添加剂，优选用于食品和药品包装应用，通过将式（1'）和/或（2'）的化合物纳入透明食品容器中，防止食品的光降解，通过在透明泡罩箔或透明药房容器中加入紫外线吸收剂来保护对紫外线A敏感的药物免受光降解的影响，作为摄影和印刷应用的添加剂，作为电子应用的添加剂，并保护农业应用中的成分。
• COSMETIC AND/OR DERMATOLOGICAL COMPOSITION CONTAINING A MEROCYANINE DERIVATIVE COMPRISING SPECIFIC POLAR GROUPS CONSISTING OF HYDROXYL- AND ETHER-FUNCTIONALITIES
  申请人：Richard Herve

  公开号：US20140294743A1

  公开（公告）日：2014-10-02

  The present invention relates to a cosmetic and/or dermatological composition comprising in a physiologically acceptable medium at least one merocyanine derivative of formula (1) or (2) and/or its E,E-, E,Z- or Z,Z-geometrical isomer forms: comprising specific polar groups consisting of hydroxyl- and ether-functionalities. Another object of the present invention relates to a cosmetic process for controlling and/or improving the darkening of the skin under exposure to UV radiation and the homogeneity of the colour of the complexion which comprises the application onto the skin of a cosmetic composition as above defined. Another object of the present invention relates to a cosmetic process for protecting the keratinic materials and particularly the skin against photo-ageing which comprises the application onto the keratinic material of a cosmetic composition as above defined.

  本发明涉及一种化妆品和/或皮肤科学组合物，其在生理上可接受的介质中包含至少一种公式（1）或（2）的merocyanine衍生物及/或其E，E-，E，Z-或Z，Z-几何异构体形式：包括由羟基和醚功能团组成的特定极性基团。本发明的另一个目的涉及一种化妆过程，用于控制和/或改善皮肤在紫外线照射下的变黑和肤色均匀性，包括在皮肤上涂抹上述定义的化妆品组合物。本发明的另一个目的涉及一种化妆过程，用于保护角质素材料，特别是皮肤免受光老化的影响，包括在角质素材料上涂抹上述定义的化妆品组合物。
• COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE, AN OILY PHASE AND A C1-C4 MONOALKANOL
  申请人：L'OREAL

  公开号：US20150335556A1

  公开（公告）日：2015-11-26

  The present invention relates to a cosmetic or dermatological composition comprising, in a physiologically acceptable support: a) at least one merocyanine compound of formula (1) or (2) and b) at least one oily phase and c) at least one C 1 -C 4 monoalkanol. The present invention also relates to a non-therapeutic cosmetic process for caring for and/or making up a keratin material, comprising the application, to the surface of the said keratin material, of at least one composition as defined above. The invention also relates to a non-therapeutic cosmetic process for limiting the darkening of the skin and/or improving the colour and/or uniformity of the complexion, comprising the application, to the surface of the skin, of at least one composition as defined previously. The invention also relates to a non-therapeutic cosmetic process for preventing and/or treating the signs of ageing of a keratin material, comprising the application, to the surface of the keratin material, of at least one composition as defined previously.

  本发明涉及一种化妆品或皮肤科学组合物，包含以下成分：a）至少一种式(1)或(2)的黄绿素化合物；b）至少一种油性相；c）至少一种C1-C4单醇。本发明还涉及一种非治疗性化妆过程，用于护理和/或化妆角蛋白质材料，包括将上述至少一种组合物应用于所述角蛋白质材料的表面。本发明还涉及一种非治疗性化妆过程，用于限制皮肤变黑和/或改善肤色和/或肤色均匀性，包括将上述至少一种组合物应用于皮肤表面。本发明还涉及一种非治疗性化妆过程，用于预防和/或治疗角蛋白质材料的衰老迹象，包括将上述至少一种组合物应用于所述角蛋白质材料的表面。
• PHOTOPROTECTIVE COMPOSITIONS COMPRISING A DIBENZOYLMETHANE DERIVATIVE, A MEROCYANINE COMPOUND AND A COMPOUND CAPABLE OF ACCEPTING THE TRIPLET EXCITED LEVEL ENERGY OF THE DIBENZOYLMETHANE COMPOUND
  申请人：L'Oreal

  公开号：EP3644954A1

  公开（公告）日：2020-05-06
• [EN] PHOTOPROTECTIVE COMPOSITIONS COMPRISING A DIBENZOYLMETHANE DERIVATIVE, A MEROCYANINE COMPOUND AND A COMPOUND CAPABLE OF ACCEPTING THE TRIPLET EXCITED LEVEL ENERGY OF THE DIBENZOYLMETHANE COMPOUND<br/>[FR] COMPOSITIONS PHOTOPROTECTRICES COMPRENANT UN DÉRIVÉ DU DIBENZOYLMÉTHANE, UN COMPOSÉ MÉROCYANINE ET UN COMPOSÉ SUSCEPTIBLE D'ACCEPTER L'ÉNERGIE D'EXCITATION DU NIVEAU D'ÉTAT TRIPLET DU COMPOSÉ DE DIBENZOYLMÉTHANE
  申请人：OREAL

  公开号：WO2019002495A1

  公开（公告）日：2019-01-03

  The present invention relates to a photoprotective composition for topical use comprising, in a cosmetically acceptable medium, at least one dibenzoylmethane derivative compound, at least one merocyanine compound and at least one compound capable of accepting the triplet excited level energy of said dibenzoylmethane derivative compound(s). The invention also relates to the use of at least one compound capable of accepting the triplet excited level energy of said dibenzoylmethane derivative compound(s), for photostabilizing with respect to UV radiation a composition comprising at least one dibenzoylmethane derivative compound and at least one merocyanine compound.