2-Methoxy-4-phenylquinazoline | 17629-09-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 2-Methoxy-4-phenylquinazoline
• 英文别名: 2-Methoxy-4-phenyl-chinazolin
• CAS: 17629-09-3
• 化学式: C₁₅H₁₂N₂O
• 分子量: 236.273
• InChiKey: BPWVJEZBXUPEQI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  18
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  35
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2-氯-4-苯基喹唑啉 、 sodium methylate 以 甲醇 为溶剂， 以90%的产率得到2-Methoxy-4-phenylquinazoline
  参考文献：
  名称：

  Hammett-Taft constants of substituted 2- and 4-quinazolinyl groups

  摘要：

  From the chemical shifts of the meta- and para-carbon atoms of the phenyl group in phenylquinazolines the sigma-I and sigma-R0 constants of 2- and 4-quinazolinyl groups were determined. Correlation equations which enable us to calculate the sigma-constants of various substituted 2- and 4-quinazolinyl groups are proposed.

  DOI：

  10.1007/bf00958004

文献信息

• Hammett-Taft constants of substituted 2- and 4-quinazolinyl groups
  作者：S. G. Baram、O. P. Shkurko、V. P. Mamaev

  DOI：10.1007/bf00958004

  日期：1991.3

  From the chemical shifts of the meta- and para-carbon atoms of the phenyl group in phenylquinazolines the sigma-I and sigma-R0 constants of 2- and 4-quinazolinyl groups were determined. Correlation equations which enable us to calculate the sigma-constants of various substituted 2- and 4-quinazolinyl groups are proposed.