3-Ethoxy-4-methylbenzonitrile | 182287-57-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 3-Ethoxy-4-methylbenzonitrile
• CAS: 182287-57-6
• 化学式: C₁₀H₁₁NO
• 分子量: 161.2
• InChiKey: APQKJXQIJNAJAO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  33
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  3-羟基-4-甲基苯腈 、 sodium;hydride 、 氧气 、 碘乙烷 以 N,N-二甲基甲酰胺 为溶剂， 以8.8 g of product were obtained的产率得到3-Ethoxy-4-methylbenzonitrile
  参考文献：
  名称：

  Thrombin inhibitors

  摘要：

  本发明涉及一种I式化合物或其生理上可耐受的酸盐，或其立体异构体，其中R1、R2、A、B、C和D的含义如规范中所述。

  公开号：

  US06900319B2

文献信息

• Novel thrombin inhibitors
  申请人：——

  公开号：US20020169318A1

  公开（公告）日：2002-11-14

  The invention relates to a compound of the formula I 1 or a salt thereof with a physiologically tolerated acid, or stereoisomers thereof, wherein R 1 , R 2 , A, B, C and D have the meanings described in the specification.

  本发明涉及一种公式I1的化合物或其生理上耐受的酸盐，或其立体异构体，其中R1，R2，A，B，C和D的含义如说明书中所述。
• Carbonyl compound scavenger and method of quantifying carbonyl compound using the same
  申请人：Sumika Chemical Analysis Service, Limited

  公开号：US07241625B2

  公开（公告）日：2007-07-10

  A carbonyl compound scavenger comprising a mineral acid salt of a benzylhydroxyamine-based compound of the formula (1) and at least one adsorbent selected from the group consisting of silica gel, alumina, cellulose and activated carbon: [wherein, R represents an alkyl group having 1 to 8 carbon atoms, haloalkyl group having 1 to 4 carbon atoms, alkoxy group having 1 to 4 carbon atoms, haloalkoxy group having 1 to 4 carbon atoms, nitro group or cyano group, and R1 and R2 represent each independently a hydrogen atom or alkyl group having 1 to 8 carbon atoms, and a hydrogen atom on a benzene ring to which a cyano group and R are connected may be substituted with an alkyl group having 1 to 8 carbon atoms, haloalkyl group having 1 to 4 carbon atoms, alkoxy group having 1 to 4 carbon atoms, haloalkoxy group having 1 to 4 carbon atoms, aryl group having 6 to 10 carbon atoms, nitro group or cyano group.].

  一种羰基化合物清除剂，包括公式（1）的苄基羟胺化合物的矿物酸盐和至少一种吸附剂，所述吸附剂选择自硅胶、氧化铝、纤维素和活性炭组成的群体中的至少一种：[其中，R代表具有1至8个碳原子的烷基，具有1至4个碳原子的卤代烷基，具有1至4个碳原子的烷氧基，具有1至4个碳原子的卤代烷氧基，硝基或氰基，R1和R2各自独立地代表氢原子或具有1至8个碳原子的烷基，并且连接到氰基和R的苯环上的氢原子可以被具有1至8个碳原子的烷基，具有1至4个碳原子的卤代烷基，具有1至4个碳原子的烷氧基，具有1至4个碳原子的卤代烷氧基，具有6至10个碳原子的芳基，硝基或氰基取代。]
• Dipeptide amidines as thrombin inhibitors
  申请人：BASF Aktiengesellschaft

  公开号：US06030972A1

  公开（公告）日：2000-02-29

  Compounds of the formula ##STR1## where A, B, D, R.sup.1 and R.sup.2 have the meanings stated in the description, are described. The compounds are suitable for controlling diseases. The novel compounds are prepared via compounds of the formula H.sub.2 N--CH.sub.2 --G--M

  化学式为##STR1##的化合物被描述，其中A，B，D，R.sup.1和R.sup.2在描述中有所说明。这些化合物适用于控制疾病。新型化合物是通过化合物H.sub.2 N--CH.sub.2 --G--M制备的。
• PYRIDONE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT
  申请人：Mitsui Chemicals Agro, Inc.

  公开号：EP3611166A1

  公开（公告）日：2020-02-19

  This is to provide a novel compound capable of controlling plants diseases. The pyridone compound of the present invention is a novel compound and can control plants diseases.

  这是为了提供一种能够防治植物病害的新型化合物。本发明的吡啶酮化合物是一种新型化合物，可以防治植物病害。
• Substituted pyridines as bromodomain inhibitors
  申请人：Zenith Epigenetics Ltd.

  公开号：US10179125B2

  公开（公告）日：2019-01-15

  The disclosure relates to substituted pyridines, which are useful for inhibition of BET protein function by binding to bromodomains, and their use in therapy.

  本公开涉及取代的吡啶，这些吡啶可通过与溴结构域结合来抑制 BET 蛋白的功能，并可用于治疗。