1-(3,5-dichlorophenyl)-3-dimethylamino-2-propen-1-one

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-(3,5-dichlorophenyl)-3-dimethylamino-2-propen-1-one
• 英文别名: 1-(3,5-Dichlorophenyl)-3-(dimethylamino)prop-2-en-1-one；(E)-1-(3,5-dichlorophenyl)-3-(dimethylamino)prop-2-en-1-one
• 化学式: C₁₁H₁₁Cl₂NO
• 分子量: 244.12
• InChiKey: BKUHHZMAJCOLAZ-ONEGZZNKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  20.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1-(3,5-dichlorophenyl)-3-dimethylamino-2-propen-1-one 在 一水合肼 作用下， 以 乙醇 、 正庚烷 为溶剂， 以90%的产率得到3-(3,5-dichlorophenyl)-1H-pyrazole
  参考文献：
  名称：

  Fungicidal arylpyrazoles

  摘要：

  本发明涉及公式(I)的3-芳基吡唑家族的新衍生物，它们的制备方法，含有它们的组合物以及它们用于保护植物免受真菌病害的利用。

  公开号：

  US05945382A1
• 作为产物：
  描述：

  3’,5’-二氯苯乙酮 、 N,N-二甲基甲酰胺 以 N,N-二甲基乙酰胺 为溶剂， 生成 1-(3,5-dichlorophenyl)-3-dimethylamino-2-propen-1-one
  参考文献：
  名称：

  [EN] ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF
  [FR] AGONISTES DU RÉCEPTEUR D'HYDROCARBURE ARYLE ET LEURS UTILISATIONS

  摘要：

  The present invention relates to pharmaceutical compounds of Formula (I): as further described herein, and pharmaceutical compositions containing such compounds, as well as methods of using these compounds to modulate the activity of aryl hydrocarbon receptor (AhR) and to treat conditions comprising inflammation inside the intestinal tract and certain disorders of the central nervous system affected by the gut-brain axis, including IBD, ulcerative colitis, Crohn's disease, Huntington's disease, and multiple sclerosis.

  公开号：

  WO2023150197A1

文献信息

• [EN] HERBICIDAL SUBSTITUTED 3-ARYLPYRAZOLES<br/>[FR] 3-ARYLPYRAZOLES SUBSTITUÉS HERBICIDES
  申请人：DU PONT

  公开号：WO2015191377A1

  公开（公告）日：2015-12-17

  Disclosed are compounds of Formula 1, including all stereoisomers, N-oxides, and salts thereof, Formula 1 wherein X1, X2, X3, G and Q are as defined in the Summary of the Inverntion; P is P1 or P2; and P1 and P2 are as defined in the Sumary of the Invention. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling undesired vegetation comprising contacting the undesired vegetation or its environment with an effective amount of a compound or a composition of the invention. Also disclosed is a herbicidal mixture comprising (a) a compound of Formula 1, and (b) at least one additional active ingredient selected from (b1) through (b16); and salts of compounds of (b1) through (b16), wherein (b1) through (b16) are as defined in the disclosure.

  本发明揭示了公式1的化合物，包括所有立体异构体，N-氧化物和其盐，公式1中X1、X2、X3、G和Q如在发明摘要中定义；P为P1或P2；P1和P2如在发明摘要中定义。此外，本发明还揭示了含有公式1化合物的组合物以及用于控制不良植被的方法，包括将不良植被或其环境与本发明的化合物或组合物的有效量接触。本发明还揭示了除草混合物，包括（a）公式1的化合物和（b）从（b1）到（b16）中选择的至少一种额外活性成分；以及（b1）到（b16）的化合物的盐，其中（b1）到（b16）如在说明中定义。
• Herbicidal substituted 3-arylpyrazoles
  申请人：FMC CORPORATION

  公开号：US10167262B2

  公开（公告）日：2019-01-01

  Disclosed are compounds of Formula 1, including all stereoisomers, N-oxides, and salts thereof, wherein X1, X2, X3, G and Q are as defined in the Summary of the Invention; P is P1 or P2; and P1 and P2 are as defined in the Summary of the Invention. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling undesired vegetation comprising contacting the undesired vegetation or its environment with an effective amount of a compound or a composition of the invention. Also disclosed is a herbicidal mixture comprising (a) a compound of Formula 1, and (b) at least one additional active ingredient selected from (b1) through (b16); and salts of compounds of (b1) through (b16), wherein (b1) through (b16) are as defined in the disclosure.

  公开了式 1 的化合物，包括其所有立体异构体、N-氧化物和盐、 其中 X1、X2、X3、G 和 Q 如发明概述中所定义；P 是 P1 或 P2；以及 P1 和 P2 如发明概述中所定义。还公开了含有式 1 化合物的组合物和控制不期望的植被的方法，包括用有效量的本发明化合物或组合物接触不期望的植被或其环境。还公开了一种除草混合物，包括(a)式1化合物，和(b)至少一种选自(b1)至(b16)的附加活性成分；以及(b1)至(b16)化合物的盐，其中(b1)至(b16)如公开内容中所定义。
• HERBICIDAL SUBSTITUTED 3-ARYLPYRAZOLES
  申请人：E I DU PONT DE NEMOURS AND COMPANY

  公开号：US20170183312A1

  公开（公告）日：2017-06-29

  Disclosed are compounds of Formula 1, including all stereoisomers, N-oxides, and salts thereof, wherein X 1 , X 2 , X 3 , G and Q are as defined in the Summary of the Invention; P is P 1 or P 2 ; and P 1 and P 2 are as defined in the Summary of the Invention. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling undesired vegetation comprising contacting the undesired vegetation or its environment with an effective amount of a compound or a composition of the invention. Also disclosed is a herbicidal mixture comprising (a) a compound of Formula 1, and (b) at least one additional active ingredient selected from (b1) through (b16); and salts of compounds of (b1) through (b16), wherein (b1) through (b16) are as defined in the disclosure.
• US5945382A
  申请人：——

  公开号：US5945382A

  公开（公告）日：1999-08-31
• Fungicidal arylpyrazoles
  申请人：Rhone-Poulenc Agrochimie

  公开号：US05945382A1

  公开（公告）日：1999-08-31

  The present invention relates to new derivatives of the family of 3-arylpyrazoles of formula (I), their methods of preparation, the compositions containing them and their utilization for the protection of plants against fungal diseases. ##STR1##

  本发明涉及公式(I)的3-芳基吡唑家族的新衍生物，它们的制备方法，含有它们的组合物以及它们用于保护植物免受真菌病害的利用。