SK5M8M | 1144040-06-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: SK5M8M
• 英文别名: 5,8-Dimethyl-5h-pyrido[4,3-b]indole；5,8-dimethylpyrido[4,3-b]indole
• CAS: 1144040-06-1
• 化学式: C₁₃H₁₂N₂
• mdl: MFCD18803673
• 分子量: 196.252
• InChiKey: KHHXRHWEGUYSSN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  15
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.153
• 拓扑面积：
  17.8
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  碳酸二甲酯 、 8-methyl-5H-pyrido[4,3-b]indole 在 potassium carbonate 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 生成 SK5M8M
  参考文献：
  名称：

  Polymethylated γ-Carbolines with Potent Anti-Bovine Viral Diarrhea Virus (BVDV) Activity

  摘要：

  Several anti-BVDV agents with a polymethylated gamma-carboline skeleton were synthesized, and their anti-BVDV activity was evaluated. The most potent antiviral agent, SK3M4M5M (20), was synthesized by Pd-catalyzed Buchwald-Hartwig amination reaction followed by annulation reaction as key steps. The structure-activity relationship was analyzed.

  DOI：

  10.3987/com-08-s(f)68

文献信息

• ORGANIC LIGHT-EMITTING DIODE MATERIALS
  申请人：President and Fellows of Harvard College

  公开号：US20180212158A1

  公开（公告）日：2018-07-26

  Described herin are molecules for use in organic light emitting diodes. Example molecules comprise at least one acceptor moiety A, at least one donor moiety D, and optionally one or more bridge moieties B. Each moiety A is covalently attached to either the moiety B or the moeity D, each moiety D is covalently attached to either the moeity B or the moeity A, and each B is covalently attached to at least one moiety A and at least one moiety D. Values and preferred values of moieties A, D and B are defined herein.

  本文描述了用于有机发光二极管的分子。示例分子包括至少一个受体基团A，至少一个给体基团D，以及可选地一个或多个桥接基团B。每个基团A与基团B或基团D中的任一基团共价连接，每个基团D与基团B或基团A中的任一基团共价连接，每个基团B与至少一个基团A和至少一个基团D共价连接。这里定义了基团A、D和B的值和首选值。
• ANTI-VIRAL AGENT CONTAINING HETEROCYCLIC AROMATIC COMPOUND AS ACTIVE INGREDIENT
  申请人：Baba Masanori

  公开号：US20100256379A1

  公开（公告）日：2010-10-07

  The present invention relates to an anti-viral agent comprising a compound represented by the following formula (I): (wherein X represents CH, a nitrogen atom, an oxygen atom, or a sulfur atom; Y and Z are the same or different and each represents a nitrogen atom or C—R 8 , and at least one of them represents a nitrogen atom; R 1 to R 8 are the same or different and each represents a hydrogen atom, a linear C 1-10 -hydrocarbon group, a hydroxy group, or a substituted or unsubstituted benzyl group; and, when X represents an oxygen atom or a sulfur atom, R 5 is absent), or the following formula (II): (wherein X′ represents CH or a nitrogen atom; Y′ and Z′ are the same or different and each represents a nitrogen atom or N—R 9 , or C—R 8 and at least one of them represents a nitrogen atom or N—R 9 ; R 1 to R 4 and R 6 to R 8 are as defined above; R 9 represents a hydrogen atom, a linear C 1-10 -hydrocarbon group, a hydroxy group, or a substituted or unsubstituted benzyl group; and, the C ring has the maximum number of double bonds at the dotted line portion) or a pharmaceutically acceptable salt thereof.
• ORGANIC PHOTOELECTRIC CONVERSION ELEMENT AND SOLAR CELL USING THE SAME
  申请人：Konica Minolta, Inc.

  公开号：US20150096610A1

  公开（公告）日：2015-04-09

  Provided are a transparent conductive film having a simple manufacturing process and high transparency, high photoelectric conversion efficiency, and excellent durability and an organic photoelectric conversion element using this transparent conductive film. The transparent conductive film of the present invention is formed by laminating a ground layer which contains a nitrogen-containing organic compound and a metal thin film layer which contains a metal element of Group 11 of the periodic table and has a thickness of from 2 to 10 nm. In addition, the organic photoelectric conversion element of the present invention has a first electrode, a second electrode, and a photoelectric conversion layer present between the first electrode and the second electrode, and at least one of the first electrode and the second electrode of the organic photoelectric conversion element is a transparent conductive film formed by laminating the ground layer which contains the nitrogen-containing organic compound and the metal thin film layer which contains a metal element of Group 11 of the periodic table and has a thickness of from 2 to 10 nm.
• US9941422B2
  申请人：——

  公开号：US9941422B2

  公开（公告）日：2018-04-10
• Polymethylated γ-Carbolines with Potent Anti-Bovine Viral Diarrhea Virus (BVDV) Activity
  作者：Hiroshi Aoyama、Kumiko Sako、Shinichi Sato、Masahiko Nakamura、Hiroyuki Miyachi、Yukinori Goto、Mika Okamoto、Masanori Baba、Yuichi Hashimoto

  DOI：10.3987/com-08-s(f)68

  日期：——

  Several anti-BVDV agents with a polymethylated gamma-carboline skeleton were synthesized, and their anti-BVDV activity was evaluated. The most potent antiviral agent, SK3M4M5M (20), was synthesized by Pd-catalyzed Buchwald-Hartwig amination reaction followed by annulation reaction as key steps. The structure-activity relationship was analyzed.