genkwain

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: genkwain
• 英文别名: genkwanin；5-hydroxy-2-(4-hydroxy-phenyl)-7-methyl-chromen-4-one；5-Hydroxy-2-(4-hydroxy-phenyl)-7-methyl-chromen-4-on；4',5-Dihydroxy-7-methylflavone；5-hydroxy-2-(4-hydroxyphenyl)-7-methylchromen-4-one
• 化学式: C₁₆H₁₂O₄
• 分子量: 268.269
• InChiKey: SDTOABMYDICPQU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  20
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  66.8
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 氢碘酸 作用下， 生成 genkwain
  参考文献：
  名称：

  Tambor, Chemische Berichte, 1908, vol. 41, p. 796

  摘要：

  DOI：

文献信息

• Safe natural pharmaceutical composition for treating cancer
  申请人：——

  公开号：US20040072790A1

  公开（公告）日：2004-04-15

  The present invention related to the natural drug of Homoharringtonine (HHT) combined with other ingredients which include Matrine (MAT), Apigenin (APN), Yejuhua lactone (YLE), Lipopolysaccharide of Kelp (LIK), Puerarin (PUN) and Indirubin (IND) for diverting human cancer cells to closely normal cells, inducing apoptosis of cancer cells and inhibiting cancer cells. Specifically, this invention provides a new method for producing HHT and other ingredients

  本发明涉及与其他成分结合的自然药物霍米哈林汀（HHT），这些成分包括苦参碱（MAT）、芹菜素（APN）、野菊花内酯（YLE）、海带脂多糖（LIK）、葛根素（PUN）和靛蓝（IND），用于将人类癌细胞转变为接近正常细胞，诱导癌细胞凋亡并抑制癌细胞。具体而言，本发明提供了一种生产HHT和其他成分的新方法。
• NONINVASIVE MEASUREMENT OF FLAVONOID COMPOUNDS IN BIOLOGICAL TISSUE
  申请人：Sharifzadeh, Mohsen

  公开号：EP2387712B1

  公开（公告）日：2014-06-04
• Inhibitors and Enhancers of Uridine Diphosphate-Glucuronosyltransferase 2B (UGT2B)
  申请人：Oliver Yoa-Pu Hu

  公开号：US20090074708A1

  公开（公告）日：2009-03-19

  A UGT2B inhibitor capable of increasing the bio-availability of a drug, is a compound in a free base or a pharmaceutically acceptable salt form that is selected from the group consisting of: capillarisin, isorhamnetin, β-naphthoflavone, α-naphthoflavone, hesperetin, terpineol, (+)-limonene, β-myrcene, swertiamarin, eriodictyol, cineole, apigenin, baicalin, ursolic acid, isovitexin, lauryl alcohol, puerarin, trans-cinnamaldehyde, 3-phenylpropyl acetate, isoliquritigenin, paeoniflorin, gallic acid, genistein, glycyrrhizin, protocatechuic acid, ethyl myristate, umbelliferone, PEG (Polyethylene glycol) 400, PEG 2000, PEG 4000, Tween 20, Tween 60, Tween 80, BRIJ® 58, BRIJ® 76, Pluronic® F68, Pluronic® F127, and a combination thereof. A UGT2B enhancer capable of enhancing a clearance rate of morphine-like analgesic agents, is a compound in a free base or a pharmaceutically acceptable salt form that is selected from the group consisting of: nordihydroguaiaretic acid, wogonin, trans-cinnamic acid, baicalein, quercetin, daidzein, oleanolic acid, homoorientin, hesperetin, narigin, neohesperidin, (+)-epicatechin, hesperidin, liquiritin, eriodictyol, formononetin, quercitrin, genkwanin, kaempferol, isoquercitrin, (+)-catechin, naringenin, daidzin, (−)-epicatechin, luteolin-7-glucoside, ergosterol, rutin, luteolin, ethyl myristate, apigenin, 3-phenylpropyl acetate, umbelliferone, glycyrrhizin, protocatechuic acid, poncirin, isovitexin, 6-gingerol, cineole, genistein, trans-cinnamaldehyde, and a combination thereof.
• PRODUCTION OF PROANTHOCYANIDINS TO IMPROVE FORAGE QUALITY
  申请人：Dixon Richard A.

  公开号：US20090083874A1

  公开（公告）日：2009-03-26

  The invention provides method and compositions for the modulation of anthocyanin and proanthocyanidin production in plants. The methods of the invention allow creation of plants having novel phenotypes. Increased expression of anthocyanins and proanthocyanidins in plants may be used to increase the nutritional value of food plants for both human and animal consumption. Increased proanthocyanidin content also reduces the potential for bloat in animals fed certain forage plants low in condensed tannin content. The invention may also be used to modify plant pigmentation, and for nutraceutical and food colorant production.
• Beverage composition and method of reducing degradation of monatin
  申请人：Roy Glenn M.

  公开号：US20100075005A1

  公开（公告）日：2010-03-25

  A beverage comprising a first ingredient which comprises a C 6 -C 3 phenylpropenoic carbonyl compound in an effective amount to reduce degradation of a second ingredient in the beverage, the second ingredient being monatin, and to reduce a corresponding change in a characteristic of the beverage. In addition, a method of preventing the degradation of monatin in a monatin-containing composition is provided.